Observation of the curative effect of mifepristone combined with infertility caused left levonorgestrel releasing intrauterine system in acetone in treatment of adenomyosis

Objective To observe the curative effect of mifepristone combined with infertility caused left levonorgestrel releasing intrauterine system in acetone in treatment of adenomyosis.Methods 60 infertility patients in our hospital from 2010 May to 2011 August were adenomyosis in patients,randomly divided into treatment group and control group two groups.Treatment group was given mifepristone 25mg orally,once a day,and even served three months.And all the patients after informed consent voluntary use of levonorgestrel releasing intrauterine system in acetone,by color Doppler ultrasound examination,by hand in 3-7 days in the menstrual medication at the same time,place left levonorgestrel releasing intrauterine system in acetone,removed after 6 months.Control group was given mifepristone 25mg orally,once a day,and even served three months.The pregnancy,3,6,1 and 12 months were observed after stopping drug.Results Statistics were followed for up to 12 months,the average conception rate of treatment group 79%,control group mean pregnancy rate was 57%,total effective rate of the treatment group was significantly higher than the control group(P0.05).Conclusion The use of mifepristone combined with left levonorgestrel releasing intrauterine system in acetone treatment of uterine adenomyosis patients can significantly improve the conception rate,the effect of adenomyosis infertility due to better than other methods,but also economic,security,convenient for patients to accept.