TREATMENT OF PULMONARY ENDOMETRIOSIS WITH A LONGACTING GnRH AGONIST
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A long-acting GnRH agonist achieved complete remission of chest symptoms in a patient with pulmonary endometriosis after surgical and other medical treatments failed.
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Abstract
We report the case of a patient who was successfully treated with a long-acting GnRH agonist for pulmonary endometriosis. This 28-year-old woman had symptomatic pleural endometriosis, documented by biopsies, as well as symptomatic pelvic endometriosis. Two surgical procedures, consisting of excision of pleural endometriotic tissue and partial pleurectomies, failed to relieve her chest symptoms. Little relief was achieved with pseudopregnancy treatment. Satisfactory symptomatic improvement was obtained with danazol, but this medication had to be discontinued because of severe side effects. Trial of a GnRH agonist, leuprolide acetate, achieved complete remission of her chest symptoms; in addition, the patient became pregnant immediately after cessation of therapy. Gonadotropin-releasing hormone agonist therapy may be an important therapeutic alternative for women with pulmonary endometriosis who cannot tolerate danazol treatment and in whom surgical therapy fails to relieve the chest symptoms.
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Cited by (9)
- Endometriosis 2021
- Thoracic Endometriosis presented as catamental hemoptysis: Fourteen Cases of a Rare Disease and the hormonal treatment management 2020
- Endometriosis 2012
- Catamenial Pneumothorax, Clinical Manifestations—A Multidisciplinary Challenge 2011
- Endometriose torácica 2008
- Endometriose torácica 2008
- Endometriosis 2007
- Video-Assisted Thoracoscopic Surgery for Catamenial Hemoptysis 2001
- A Case of Endobronchial Endometriosis Treated by Subsegmentectomy 1999
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