Hydrogel droplets are generated and manipulated in a cylindrical cavity microfluidic environment- digital twin

Hydrogel droplets are generated and manipulated in a cylindrical cavity microfluidic environment- digital twin | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Hydrogel droplets are generated and manipulated in a cylindrical cavity microfluidic environment- digital twin Peiyuan HE This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8610524/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract This exploratory work focused on the hydrogel droplet generation and the numerical analysis for the digital twin. Hydrogel droplet technology has a wide range of applications in scientific research and engineering, and this paper reviews the hydrogel generation technology. The correlation analysis was carried out on the microfluidic droplet generation process under different experimental conditions, and the digital twin was discussed for the generation of microdroplets in the cylindrical cavity. The experiment mainly studied the size of the generated hydrogel microspheres by changing the concentration, flow velocity and pinhole diameter of the sodium alginate hydrogel solution. The experimental results show that the size of the droplets is positively correlated with the three experimental conditions, and is significantly correlated with the concentration of microfluidic solution and pinhole diameter. In this experiment, the role of three independent droplet generation factors is studied at the same time, which provides a digital twin technology basis for the realization of microfluidic hydrogel droplet generation. Numerical Analysis Biopolymers Biophysics microfluidics hydrogel droplet technology digital twins Relevance Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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