GYNECOLOGICAL STATUS OF PATIENTS WITH THE HISTORY OF DIFFUSE APPENDICULAR PERITONITIS IN CHILDHOOD

To study the state of the patient’s gynaecological status, who sustained appendicular peritonitis in childhood

There were 154 girls and women who sustained diffuse appendicular peritonitis between 3 to 15 years old. Patients were operated between 1998 to 2014, contained the main group (n=104; 67.5%). 50 (32.5%) patients operated between 1990 to 1997 years were included to the control group. In patients of the main group, a complex of anti-adhesive measures was carried out according to the technique developed by authors. Patients of control group were operated according to the traditional, generally accepted approaches. Catamnesis data were analyzed between 2 and 15 years after surgical interventions.

In the long-term period, the 154 patients have conducted a comprehensive diagnostic of the reproductive function. Normal regular menstruation was observed in 120 (81.1%) patients, in 82 (83.7%) of the main group, and 38 (76%) – in the control group. The others have reported various violations of menstrual functions: (dis-, oligo- and polymenorrhea). In the ultrasound, cystic changes in ovaries show 24.4% in the control group; and in 17.5% in the main group; pelvic adhesions in 26.7% and 15%, respectively. 42 female of the control group and 24 of the main group underwent echohysterosalpingoscopy and hysterosalpingography. Different forms of the fallopian tubes abnormalities in the control group were 50%, whereas the patients of the main group have 29.2%. The luteinizing hormone level was below in the main group. The level of progesterone and estradiol was also lower in the main group than in the control group.

Analysis of the causes of reproductive system disorders showed that the history of appendicular peritonitis in childhood, is possibly one of the factors in the development of tubal and peritoneal forms of infertility in the long-term period.

Girls, appendicular peritonitis, long-term results, reproductive function , infertility.

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Authors' information: Yusupov Shukhrat Abdurasulovich Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery, Samarkand State Medical Institute ORCID ID: 0000-0001-7259-028X SPIN: 3576-7390 Author ID: 554847 E-mail: [email protected] Shamsiev Azamat Mukhitdinovich Doctor of Medical Sciences, Full Professor, Professor of the Department of Pediatric Surgery, Samarkand State Medical Institute Researcher ID: AAB-4891-2019 Scopus ID: 57204509652 ORCID ID: 0000-0002-3628-9825 E-mail: [email protected] Shamsiev Dzhamshed Azamatovich Doctor of Medical Sciences, Full Professor, Head of the Department of Pediatric Surgery, Anesthesiology and Intensive Care, Faculty of Postgraduate Education, Samarkand State Medical Institute Researcher ID: AAM-8222-2020 Scopus ID: 57195308203 ORCID ID: 0000-0003-3751-2352 E-mail: [email protected] Davranov Bоbur Latipovich Candidate of Medical Sciences, Assistant of the Department of Pediatric Surgery, Anesthesiology and Intensive Care, Faculty of Postgraduate Education, Samarkand State Medical Institute ORCID ID: 0000-0002-6411-2920 Author ID: 15871812 SPIN: 7740-7311 E-mail: [email protected] Information about support in the form of grants, equipment, medications The authors did not receive financial support from manufacturers of medicines and medical equipment Conflicts of interest: No conflict Address for correspondence: Yusupov Shukhrat Abdurasulovich Doctor of Medical Sciences, Associate Professor, Head of the Department of Pediatric Surgery, Samarkand State Medical Institute 140100, Republic of Uzbekistan, Samarkand, Amir Temur str., 18 Tel.: + 998 (915) 481613 E-mail: [email protected] This work is licensed under a Creative Commons Attribution 4.0 International License.

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