Effect of endometriosis on in vitro fertilization and embryo transfer

Objective To investigate the IVF outcome for patients with endometriosis.Methods Eighty-six patients with endometriosis underwent 94cycles of IVF-ET.The control group with tubal-factor infertility consisted of 200 cycles in 200 patients.These groups were retrospectively analyzed regarding COH,embryo development,implantation,and pregnancy outcome.Results The requirement of gonadotropin significantly higher( P 0 01),the number of oocytes retrieved significantly smaller,the fertilization rate significantly lower( P 0 05) in women with endometriosis compared with controls.There was no significant difference in implantation rate,pregnancy rate.Conclusions Women with endometriosis presented a poor ovarian response to controlled ovarian hyperstimulation,a significantly lower fertilization rate and decreased tendency of implantation and pregnancy rate compared to the women with tubal factors.