OP33.01: The impact of endometriosis and its staging on assisted reproduction outcomes: a systematic review and meta‐analysis

Evaluate whether the presence or severity of endometriosis affect the outcomes of assisted reproductive techniques (ART). In this systematic review all studies comparing the ART outcomes of women with and without endometriosis or at different stages of the disease were considered eligible. Our primary outcome was live birth; the secondary outcome was clinical pregnancy. Miscarriage and the number of oocytes retrieved were examined as additional outcomes. We included 90 studies in the review and 76 in the meta-analysis: 20,167 women with endometriosis were compared with 121,931 women without endometriosis; and 1,703 women with endometriosis III/IV were compared with 2,227 women with endometriosis I/II. The results are summarized in the table. Women with endometriosis undergoing ART have practically the same chance of achieving clinical pregnancy and live birth than women with other causes of infertility. No relevant difference was observed in the chance of achieving clinical pregnancy and live birth following ART when comparing endometriosis III/IV with endometriosis I/II. The quality of the evidence for the additional examined outcomes was very low, not allowing meaningful conclusions. OP33.01: Table 1.