A systematic review of blunt abdominal aortic injury and analysis of predictors for death

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Little is known about this disease. So, a systematic review was conducted through extensive search of major databases. All literature that provided individual (non-identifiable) data for BAAI patients could be included without being limited by study design. Additionally, regression analyses of predictors for death after BAAI were conducted. The search resulted in 2,099 hits, and 102 case reports and 1 conference abstract included in the review then. After assessment using the Joanna Briggs Institute checklist, no low-quality studies were found. A total of 133 patients were included, with a median age of 34 and 73.7% being males. Their most common clinical manifestation was pain (65.6%). The most common severity of aortic lesion was grade A (intimal tear or intramural hematoma, 46.9%), and the most common location of aortic lesion was zone III (infrarenal aorta, 88.3%). The overall mortality after BAAI was 15.3%. The following are the predictors for death after BAAI identified through multivariate regression analyses: lower limb ischemia [relative risk (RR), 7.137; 95% confidence interval (CI), 1.154-44.161], cardiopulmonary arrest (RR, 10.250; 95% CI, 1.452-72.344), and injuries to other parts (other than abdomen and lumbar spine) of body (RR, 2.593; 95% CI, 1.189-5.655). In conclusion, this study provides a detailed quantitative summary of the characteristics of the clinical manifestations, diagnosis, treatment, and prognosis of BAAI, a deadly traumatic disease, and indicates that the three variables above are risk factors for death. BAAI blunt trauma abdominal injury mortality trauma Figures Figure 1 Figure 2 Figure 3 Introduction Blunt abdominal aortic injury (BAAI) is believed to be caused by the injury to the aorta relates to the blunt biomechanical direct and indirect forces incurred on the abdominal aorta, which is tethered between the spinal column and the peritoneum and abdominal viscera [1]. It is rare both in adults and children [2]. According to previous studies, it represented only 4-6% of total aortic injuries and less than 1% of total blunt trauma [3-5]. Although uncommon, it is lethal. A high but variable mortality with published rates ranging from 17% to 92% was demonstrated by previous studies [5-8]. Compared with blunt thoracic aortic injury (BTAI), BAAI is much less common. This is thought to be due, in part, to the relatively fixed position of the entire length of the abdominal aorta compared with the thoracic aorta’s fixation only at the ligamentum arteriosum, and base of the heart [9]. For ease of exposure and repair at the time of surgery, Shalhub et al. divided all aortic lesion locations into 3 types [1]. This classification method was favoured by many researchers [10, 11]. On the other hand, for BTAI or nonspecific blunt aortic injury (BAI), researchers have developed many grading criteria for the severity of aortic lesions according to the pathological changes of injured aorta [12-15]. However, there are few studies on the effect of aortic lesion location and severity on the prognosis of BAAI patients. The therapeutic methods of BAAI mainly consisted of operation and conservative observation. Kondo et al. reported that the 24-h mortality and the hospital mortality of BAAI did not differ statistically among the various treatment modalities [16]. However, Sheehan et al. showed that patients who underwent aortic surgery had a statistically lower mortality than those who had not [17]. Other studies in this area are very few. The only few previous studies did not address much of the core knowledge about BAAI, which makes us poorly understood about this dangerous traumatic disease. So, we conducted this worldwide systematic review. It was registered with PROSPERO (CRD42023408842) within accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework [18]. Materials And Methods Ethical statement As this is a review based on published literatures and does not contain any individual identification information, ethical approval and consents to participate are not required, which is in line with local regulations and policies. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). Search strategy A systematic search in the Excerpta Medica Database, PubMed, Web of Science, and Cochrane Library was performed on December 23, 2022. All words synonymous with or similar to “abdominal aortic injury” were searched to eliminate omissions. The full search strategy is showed in Supplemental File 1. Study selection The abdominal aorta was defined as the aorta from the diaphragm to the bifurcation into the right and left common iliac arteries. The samples were set as human individuals with BAAI who suffered any kinds of injury on abdominal aorta due to blunt or non-piercing external force causes. All brief information of the searched articles was imported into Endnote X9 for duplicate removal and brief review. Then, the full texts of all available articles that passed the preliminary screening were downloaded and reviewed to identify those that were finally included in the study. The available ones from articles about abdominal aortic injury (AAI) obtained through primary search were all selected initially. And then, not limited by study design, any literature that reported individual data on BAAI patient could be included, allowing for missing values on variable. The exclusion criteria included (1) samples with concomitant thoracic aortic injury; (2) samples with pre-existing dilative aortic disease (such as aortic aneurysm) or aortic injury; (3) samples suspected of duplication; (4) articles which were published in non-English. If some of the BAAI samples reported in a certain article met the above selection criteria, they would be selected for inclusion in the presented review. Two authors (ML and CW) independently performed the data selection separately. Any discrepancies were resolved by consensus. Data extraction Multiple variables of BAAIs as detailed as possible were set up for data extraction. The definitions and descriptions of each variable are shown in Supplemental File 2. Specifically, the “death after BAAI” was defined as any death due to the initial traumatic cause but excluding other causes such as a malignant cancer. The locations of aortic lesions were divided into 3 location zones [zone I (the zone from diaphragmatic hiatus to superior mesenteric artery (SMA), II (the zone including SMA and renal arteries), and III (the zone from infrarenal aorta to aortic bifurcation)] according to the method of Shalhub et al. [1]; and the injury severities of aortic lesions were divided into 5 grades {grade A (intimal tear or intramural hematoma), B [small pseudoaneurysm (less than 50% circumference)], C [large pseudoaneurysm (more than 50% circumference)], D (intraluminal truncation), and E (rupture)} further on the basis of Rabin et al.’s method [15]. Data extraction was performed by a pair of independent authors (HT and HZ). If, according to our definitions, the value (or classification) of a variable in an included article was not directly reported, these two authors will make independent judgments based on the description in the original text. Any queries and discrepancies were resolved through further discussion to reach a consensus. Quality assessment The original studies were assessed by the Joanna Briggs Institute (JBI) checklist for case reports [19]. This tool includes 8 items, which evaluate whether the descriptions of the clinical characteristics, diagnosis, treatment, outcome, and other aspects on the patients in every report are comprehensive and clear. The item is scored 1 point if answer “yes” or “not applicable” and scored 0 point if answer “no” or “not clear”. If multiple cases were reported separately by some study, they would be evaluated separately, and the score of the whole study would take the lowest value of those of the cases. All included studies were classified as having “low” (0-3 points), “medium” (4-6 points), or “high” (7-8 points) methodological quality. Three independent authors (ML, ZG and LG) each finished quality assessments for all included articles. If opinions differed, the lower score was taken. Statistical analysis Continuous variables were presented as “mean ± standard deviation” or “median with interquartile range (IQR)”, and categorical ones were presented as “number with percentage”. Statistical analyses were conducted using the Stata version 16.0 software (StataCorp., College Station, TX, USA). All hypothesis tests were two-sided, and P <0.05 was considered to indicate a statistical difference. The age distributions of BAAI patients between genders were compared, using the Mann Whitney U test [20]. The constituent ratios of all samples in categorical variables were also calculated separately. The details of patients who died after BAAI were also described. Setting the binary “death after BAAI” as outcome variable, the potential predictors were explored. Except obviously unrelated ones such as “diagnostic method”, all variables were entered into a binomial family generalized linear model (GLM) (link: log; standard error type: default; optimization method: maximum likelihood estimation) one by one for univariate regression analyses, using the relative risk (RR) with 95% confidence interval (CI) as measure [21]. To obtain a likely positive outcome while retaining as much detail as possible for categories, we tried multiple combinatorial modalities of core treatments and substituted the derived variables into the model separately. Then we attempted to simultaneously bring the obtained variables with P value <0.20 into the above GLM for adjusted multivariate regression analysis. But the model failed to converge and could not derive a result. So, a multivariate regression analysis of these variables using a robust Poisson family GLM (link: log; standard error type: robust; optimization method: maximum likelihood estimation) was performed. Only those variables with a P value <0.05 and an absolute RR value <1000 were accepted and considered as predictor. To assess the fitting ability, we also recorded the value of Akaike information criterion (AIC) [22] and log pseudolikelihood [23] of the final adopted regression model. Additionally, using Fisher’s exact test [24], patients with the calculated predictors were selected for subgroup analyses, to explore the influences of different treatment modalities on mortality in these specific patients. All statistical analyses were conducted by ML. Results Characteristics of studies and patients The systematic search yielded a total of 2,099 articles before 1,123 duplicates were removed, following which 766 ones were excluded after title abstract sieve. Finally, 103 articles were included after full text assessment [25-127] (Supplemental File 3). These articles included 102 case reports and 1 conference abstract. Of them, there were 14 (13.6%) ones which included multiple (2 to 7) cases. After quality assessment, there were 91 high-quality studies (88.3%), 12 medium-quality ones (11.6%), and no low-quality ones. All they were published from 1961 to 2021, of which 83 (80.6%) were published after 1990. And there were 25 reporting countries, with USA reporting the most frequently (48, 46.6%). One patient was injured abroad but went to USA later for treatment and was reported by American doctors [31]; the remaining patients were considered to have been injured and treated (if happened) in the reporting country. The authors of one article published in 2018 were from Serbia and Montenegro respectively [98], and the reporting country of this article was considered to be one rather than two. A total of 133 BAAI patients at a median age of 34 (IQR, 17-54) (ranged from 1 to 89) were included. The detailed characteristics of the included studies and patients are shown in Supplemental File 4. Among the patients, there were 35 females (26.3%), who were generally older than males ( P = 0.012) (Supplemental File 5). Clinical manifestations, diagnoses, treatments, and outcomes The most common injury way of BAAI patients was the “direct strike (non seat belt)” (collision, fall, gas shock, etc.), accounting for 53.4%. The various clinical presentations of all patients were classified into 4 categories, with pain being the most common (65.5%). In addition, 5.0% of patients presented with cardiopulmonary arrest and 36.4% with shock. And taking the first day after trauma as the boundary, 11.8% of patients experienced delayed manifestations, while 4.2% had no acute manifestations. The constituent ratios of clinical manifestation variables are shown in Figure 1. The most common diagnostic method was computed tomography (CT), accounting for 52.6%. Three patients were not diagnosed with BAAI until 7 months, 8 years, and 9 years after trauma respectively due to different reasons [41, 43, 58]. According to the established classifications, 88.3% of patients had an aortic lesion located in zone III, and 47.0% were grade A severity. Thrombosis at the aortic lesion was reported in 28.8%, and 78.3% were reported to have aortic degeneration. In addition, 66.9% of patients were injured to other organs in abdomen, 25.6% were injured to lumbar spine, and 23.3% were injured to other parts of body. Concomitant injuries up to 7 organs or tissues after trauma was reported in one patient [102]. Among all injured organs in abdomen, the gastrointestinal tract was the most common, accounting for 49.6% of all 133 BAAI patients. The constituent ratios of diagnosis variables are shown in Figure 2. The most common treatment modality was primary open surgery (OS, 55.2%), followed by primary endovascular therapy (EVT, 24.0%) and others. One patient underwent percutaneous aortic stent implantation after failed conservative observation, but it was found intraoperatively that the stent migrated to suprarenal aorta, so he underwent open aorto-aortic bypass and recovered well [91]. He was considered to have received a secondary OS as the core treatment modality. Among the 114 patients who underwent operation treatment, the choice of their approach (OS or percutaneous EVT) was not statistically associated with the presence of neither injuries to organs in abdomen, to lumbar spine, or to other parts of body ( P = 0.144, 0.240, and 0.486, respectively). The same situation also arised whether the gastrointestinal tract which was the most representative abdominal organ, was injured, i.e., of the 114 patients who underwent operations, 60 had gastrointestinal injury, and 29 of them underwent OS rather than EVT ( P >0.999). After categorizing the timing of core treatment after injury, it was found that most patients were treated rapidly (within 3 days after injury) (64.5%). One patient received OS immediately after reception [43], whereas another patient was not treated until 9th year after injury because of a missed diagnosis [44]. The longest follow-up was 10 years [105]. 27.1% of patients had various non-fatal adverse events after treatment, of which acute renal failure was most common (47.8%). Some patients had up to 4 kinds of adverse events after OS, excluding multiple organ dysfunction syndrome [43, 45]. 5.0% and 10.0% of patients had residual chronic lower limb ischemia and neurological dysfunction as sequelae after treatment respectively. Finally, it was found that 19 patients (15.3%) died after BAAI. They were classified according to the time of death (Table 1). The constituent ratios of treatment and outcome variables are shown in Figure 3. Among the 53 cases with available data who had gastrointestinal injury and underwent operations, 3 died after BAAI in the OS group and none in the EVT group, which did not suggest a statistical difference ( P = 0.543). Death after BAAI Due to failed convergence of the binomial regression model after selecting variables through univariate analyses, a robust Poisson GLM was taken for analysis and then derived several variables with P <0.05. However, the absolute RR values of some of these variables (including all the multiple categorical ones) are very exaggerated exceeding 1000, even reaching trillions. Therefore, multiple stepwise regression approaches (forward, backward, etc.) were taken in an attempt to find variables that destabilized the model. Then, a stable Poisson regression model with 86 observations included was obtained after excluding all multiple categorical variables. The AIC value of this model was 1.018, and the log pseudolikelihood value was -34.776. We collected all the variables in this model and tried the binomial regression again, but still failed in convergence. So, the Poisson regression model was adopted finally, and 3 statistically significant predictors (i.e. risk factors) for death after BAAI were obtained, which were lower limb ischemia (RR, 7.137; 95% CI, 1.154-44.161; P = 0.035), cardiopulmonary arrest (RR, 10.250; 95% CI, 1.452-72.344; P = 0.020), and injuries to other parts of body (RR, 2.593; 95% CI, 1.189-5.655; P = 0.017). The analysis details are shown in Table 2, and the adopted model results are also presented in a forest plot (Supplemental File 6). After subgroup analyses, it was found that the mortality of BAAI patients with lower limb ischemia or injuries to other parts of body, whether undergoing primary operation or secondary operation, was lower than that of those who received conservative observation ( P = 0.020 and 0.035 respectively); however, the mortalities with cardiopulmonary arrest did not differ significantly among different treatment modalities ( P >0.999). The details are shown in Supplemental File 7. Discussion Significance of this study In this review, the multifaceted characteristics of BAAIs and risk factors for death were revealed. This can help clinicians to better recognize this rare but fatal traumatic disease and to take more timely and accurate treatment for high-risk patients. Characteristics of BAAIs Most studies on BAAI were all case reports, showing the scarcity of BAAI. Among the 133 included BAAI patients, the median age of males was significantly lower than that of females (32 vs. 45, P = 0.012). The reason may be that men in adolescence or youth prefer to be exposed to intense activities, such as driving motor vehicles, playing football, boxing. A direct blunt external force of sufficient magnitude can cause BAAI, and this type of trauma accounted for the majority (53.4%) in this review. While the proportion of patients who did not have a direct crash but were restricted by the seat belt and thereby developed a BAAI also reached 43.1%. We have recognized that the mechanism caused by these injury modalities is the combined compressive effect on the abdominal aorta (AA) by the anteriorly located abdominal viscera and the posteriorly located lumbar spine, associated with sudden deceleration [99, 128]. Meanwhile, we also found 4 (3.4%) patients who did not suffer any direct external force applied to abdomen, and their cause of injury was classified as back hyperextension that caused excessive traction on AA [82, 83, 88, 100]. Additionally, regardless of the injury way, damage to the lumbar spine may promote the development of BAAI due to the increased local force to AA [46, 47, 82]. The presented review shows that the clinical manifestations of BAAI patients are diverse. In addition to shock and cardiopulmonary arrest in severe cases, pain, lower limb ischemia, and neurological dysfunction were representative. Among them, the proportion of patients with pain in abdomen, chest, back, or lumbar flakes reached 65.5%, suggesting that pain may be the most common clinical symptom of BAAI patients. In addition to pain and lower limb ischemia due to reduced blood flow, we also found that 12.6% of patients had neurological dysfunctions with different degrees, such as paraplegia, hypoesthesia, asynodia and so on. The reason may be the direct injury of the lumbosacral spinal cord or plexus, or the damage of Adamkiewicz artery originating from AA and supplying blood directly to the lumbosacral spinal cord [129]. The majority (52.6%) of BAAIs were diagnosed by CT. It shows that CT has become the most important imaging examination for the diagnosis of BAAI, which is also in line with the views of many researchers [10, 130]. Up to 88.3% of patients’ aortic lesions were in zone III which is from infrarenal aorta to the aortic bifurcation. However, there were only 15 cases of injury located in zone I (supra-SMA) and zone II (SMA to renal arteries). The reason may be that infrarenal AA is less protected compared with suprarenal AA [131]. Meanwhile, after regression analyses, there was not enough evidence to prove that different injury locations affected the mortality rate of BAAI. Severity grading criteria for aortic lesion have not been uniform [10, 15, 132]. After comparison, we referred to Rabin et al.’s method on BAI [15]. However, intimal tears belong to the mildest grade (grade A) by this grading standard, but apparently the large aortic dissections (ADs) with or without thrombosis leading to luminal obstruction cannot meet any grade including A. So, we add this severe AD as the grade D which was only milder to grade E (rupture) on the basis of this standard. Then we found that even so, the proportion of BAAI patients of the mildest grade A remained the highest (47.0%). This suggests that most BAAI patients have a mild damage on AA. Aortic degenerative pathology was present in 78.3% of patients and lumbar spine fractures in 25.6% with relevant reports. These two conditions may increase the susceptibility of trauma patients to BAAI based on the pathogenic mechanism theory that AA is compressed, and this is also in line with the ideas in several studies [18, 131]. The treatment of choice for BAAI patients by most clinicians was primary OS (55.2%), and the proportion of primary operation including primary EVT had even reached 79.2%. This suggests that the application of conservative treatment in BAAI is still limited. However, not all BAAI patients face the same risks obviously. Shalhub et al. believed that whether operation should be performed and which operation modality should be chosen depend on the location and severity of the aortic injury [1, 6]. Additionally, the results of this presented review suggest that clinicians’ choices of operation modality were not related to the presence of injuries to other tissues or organs (especially those in abdomen). We believe that part of the reason for this is the habits and preferences of various medical centers and clinicians. Generally, the causes of some unwanted or unexpected events in BAAIs could not be explained as traumatic or iatrogenic alone. So we collectively referred to these negative events after treatment (including conservative observation) as “adverse events” (excluding death). And we found that its proportion was 27.1%, which was similar to a previous study [17]. After excluding deaths that were apparently unrelated to BAAI (such as malignancies years later), the mortality after BAAI in the presented review was 15.3% (n = 19). The immediate cause of death in these patients was mostly haemorrhage after AA injury, even after treatments. Predictors for death after BAAI The analysis results show that, the risk of death after BAAI is increased in patients with lower limb ischemia, cardiopulmonary arrest, or injuries to other parts of body. We believe that only severe AA injuries such as grade D/E are sufficient to cause lower extremity ischemic symptoms. So, the variable of lower limb ischemia can directly reflect the severity of ischemia caused by aortic injury. And acute limb ischemia is associated with many serious consequences including death, which has long been proved [133, 134]. The preliminary multivariable model did show that the severity of aortic disease (multiple categorical variable) directly influenced the mortality ( P <0.001), but it was not adopted because of unusual RR values (over 1000). On the other hand, cardiopulmonary arrest and injuries to other parts of body both mean the severity of trauma to the whole body, not just to AA. In other words, other simultaneous injuries may also lead to death or aggravate the impact of AA injury on the body. It is very difficult to explore the specific initial cause of death of a patient with multiple injuries. Additionally, we also removed some variables because of their exceeded 1000 RR values. For example, the mortalities of zone I and II injuries that were more difficult to be exposed or controlled by OS were higher than that of zone III injuries, secondary EVT after failed conservative observation was associated with higher mortality than conservative treatment throughout, and so on. They should not be easily negated although not proven to be statistically valuable, because of the theoretical plausibility. The reason for the unusual RR values estimated is the small available sample size, likely. We look forward to more studies with large sample sizes. Results of subgroup analyses suggest that, compared with conservative observation, both primary and secondary operation treatment (including OS and EVT) for BAAI patients with lower limb ischemia or injuries to other parts of body can reduce the risk of death ( P <0.05). This proves the importance of operation treatment for the BAAI patients at high-risk. Meanwhile, the differences in protective effects between the three treatment modalities are not reflected among BAAI patients with cardiopulmonary arrest. Also due to the small sample size (n = 2 for this subgroup), we cannot easily make a conclusion that operation cannot play a role in reducing the risk of death in such BAAI patients. Limitations This review also has some limitations. First, since there were no uniform standards among the references, the descriptions of the variables were sometimes vague, affecting the accuracy of data extraction and analysis. Second, cases with good curative effect might be easier to be reported and published, while those that have unsatisfactory outcomes for various reasons might not. This may make the true mortality underestimate, increasing the publication bias. Conclusions BAAI is a lethal injury with diverse characteristics and a mortality rate of 15.3% at least. The increased mortality risk of BAAI is associated with lower limb ischemia, cardiopulmonary arrest, and injuries to other parts (other than abdomen and lumbar spine) of body. Operation (including OS and EVT) can reduce the mortality of BAAI patients with lower limb ischemia or injuries to other parts of body, even as a salvage measure after failure of conservative observation. Declarations ACKNOWLEDGMENTS None. Conflicts of interest: Authors declare no conflicts of interest. Funding: Authors received no specific funding for this work. Data availability: The original data is available from the corresponding author on reasonable request. References Shalhub S, Starnes BW, Tran NT, Hatsukami TS, Lundgren RS, Davis CW, et al. Blunt abdominal aortic injury. J Vasc Surg 2012;55(5):1277-85. Sadaghianloo N, Jean-Baptiste E, Breaud J, Declemy S, Kurzenne JY, Hassen-Khodja R. Blunt abdominal aortic trauma in paediatric patients. Injury 2014;45(1):183-91. Nucifora G, Hysko F, Vasciaveo A. 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[ 60 ] 19 M DS CA, S G E A, O - <1d Hemorrhage - David et al. [ 78 ] 54 F DS P, LLI Z II, G A, T A, O - 2d Respiratory failure - Desai et al. [ 92 ] 78 F DS CA, S Z II, G A, AD No - <1d Hemorrhage - After diagnosis and before initial treatment 1 (5.3) Harkin et al. [ 8 ] 7 M DS P, LLI, S Z III, G E No - <1d Hemorrhage - During operation 2 (10.5) Hewitt et al. [ 12 ] 65 M SB LLI, OM Z III, G D, T, AD A POS, <3d <1d N/A N/A Gordon et al. [ 93 ] 46 F DS CA, S Z II, G E LP POS, <3d <1d Hemorrhage Spinal cord injury After initial treatment 10 (52.6) Reisman et al. [ 14 ] 55 F DS P, LLI, ND, OM Z III, G E, T, AD A, O POS, <3d 2mo MODS MODS Bergqvist et al. [ 19 ] 66 F SB P, LLI Z III, G E, T, AD No POS, <3d 9d Septic shock MODS, Poor wound healing Sadaghianloo et al. [ 29 ] 15 M DS N/A Z III, G B A CO, <3d <1d Hemorrhage N/A Frydenburg et al. [ 30 ] 78 M SB LLI G A, T O CO, <3d <1d Respiratory and renal failure Respiratory and renal failure Frydenburg et al. [ 30 ] 71 F SB LLI Z III, G D O CO, <3d 2d Respiratory and renal failure Respiratory and renal failure Michaels et al. [ 31 ] 60 F SB LLI, OM, S Z III, G D A POS, <3d 4d N/A N/A Nucifora et al. [ 33 ] 36 M DS OM, S Z III, G E No POS, <3d <1d Hemorrhage N/A Tracy et al. [ 42 ] 13 M DS OM, S Z III, G E O POS, <3d <1d Hemorrhage No Macbeth et al. [ 69 ] 60 M DS P, LLI, ND Z III, G D, T, AD A POS, 30d-1y 1.5mo Septic shock Septic shock, renal failure Warrian et al. [ 76 ] 36 F SB LLI, OM Z III, G E, AD O POS, <3d 19d MODS MODS On missed diagnosis 1 (5.3) Katsoulis et al. [ 37 ] 41 M DS P, LLI, ND N/A A, LP - 9d Hemorrhage No BAAI: blunt abdominal aortic injury; M: male; F: female; DS: direct strike; SB: seat belt; CA: cardiopulmonary arrest; S: shock; P: pain; LLI: lower limb ischemia; OM: other manifestations; ND: neurological dysfunction; Z: zone; G: grade; T: thrombosis; AD: aortic degeneration; N/A: not available; A: injuries to organs in abdomen; LP: injuries to lumbar spine; O: injuries to other parts of body; POS: primary open surgery; CO: conservative observation; MODS: multiple organ dysfunction syndrome Table 2. Univariate and multivariate analysis of death after BAAI Variable Univariate analysis Multivariate analysis 1 † Multivariate analysis 2 ‡ Num of obs Relative risk (95% CI) P value Relative risk (95% CI) P value Relative risk (95% CI) P value Age (y) 124 1.018 (1.001-1.035) 0.040 1.054 (1.019-1.090) 0.002 1.004 (0.988-1.020) 0.598 Female 124 2.182 (0.966-4.929) 0.061 0.494 (0.098-2.499) 0.394 1.794 (0.788-4.083) 0.164 Injury way 104 Direct strike Reference Seat belt 0.851 (0.335-2.166) 0.735 Back hyperextension 1 - Pain 110 0.264 (0.108-0.648) 0.004 0.263 (0.100-0.689) 0.007 0.967 (0.255-3.659) 0.960 Lower limb ischemia 110 2.106 (0.883-5.023) 0.093 8.170 (0.738-90.486) 0.087 7.137 (1.154-44.161) 0.035 Neurological dysfunction 110 1.267 (0.416-3.857) 0.677 Other manifestations 110 1.397 (0.577-3.379) 0.459 Cardiopulmonary arrest 110 6.667 (3.580-12.415) <0.001 2.70e+07 (1.62e+06~4.50e+08) <0.001 10.250 (1.452-72.344) 0.020 Delayed manifestations 110 0.439 (0.064-3.030) 0.403 No immediate manifestations 106 1 - Shock 99 2.207 (0.976-4.990) 0.057 2.715 (0.603-12.224) 0.193 2.552 (0.799-8.152) 0.114 Aortic lesion location 113 Zone I 1 - 9.28e-08 (1.86e-08~4.64e-07) <0.001 Zone II 3.281 (1.159-9.293) 0.025 2.82e-07 (5.07e-08~1.57e-06) <0.001 Zone III Reference Reference Aortic lesion severity 111 Grade A Reference Reference Grade B 4.143 (0.429-40.050) 0.219 5.97e+05 (9.29e+04~3.84e+06) <0.001 Grade C 1 - 2.93e+05 (2.59e+04~3.33e+06) <0.001 Grade D 6.444 (1.284-32.334) 0.024 8.45e+11 (1.09e+11~6.58e+12) <0.001 Grade E 11.393 (2.706-47.968) 0.001 2.06e+12 (2.99e+11~1.42e+13) <0.001 Thrombosis at aortic lesion 110 1.750 (0.659-4.648) 0.261 Aortic degeneration 23 0.972 (0.287-3.292) 0.964 Injuries to organs in abdomen 124 0.569 (0.251-1.292) 0.178 0.909 (0.399-2.071) 0.821 0.624 (0.273-1.426) 0.263 Injuries to lumbar spine 124 0.914 (0.330-2.534) 0.863 Injuries to other parts of body 124 2.700 (1.209-6.031) 0.017 4.775 (0.387-58.855) 0.222 2.593 (1.189-5.655) 0.017 Core treatment 102 Primary operation 0.363 (0.115-1.142) 0.083 2.882 (0.519-15.994) 0.226 Secondary operation 1 - 3.12e+04 (7.06e+03~1.38e+05) <0.001 Conservative observation Reference Reference Timing to core treatment after injury 91 <3d Reference 3d-30d 1 - 30d-1y 0.363 (0.051-2.603) 0.313 ≥ 1y 1 - Adverse events 23 1 - Residual lower limb ischemia 95 1 - Residual neurological dysfunction 10 1 - BAAI: blunt abdominal aortic injury; Num of obs: number of observations; CI: confidence interval † All variables with a P value <0.20 from univariate analysis were included in the model; ‡ Variables with a P value <0.20 from univariate analysis and a relative risk value <1000 from multivariate analysis 1 were included in the model Additional Declarations No competing interests reported. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-2703023","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":186015123,"identity":"4ae24672-068a-4c65-9da7-f3ed7b1b949c","order_by":0,"name":"Mingxuan Li","email":"","orcid":"","institution":"Beijing Fengtai You’anmen Hospital","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Mingxuan","middleName":"","lastName":"Li","suffix":""},{"id":186015124,"identity":"c4cb89a6-422e-4926-b4d0-731435c87290","order_by":1,"name":"Chaonan Wang","email":"","orcid":"","institution":"Chinese Academy of Medical Science \u0026 Peking Union Medical College","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Chaonan","middleName":"","lastName":"Wang","suffix":""},{"id":186015125,"identity":"4dbda628-d184-4cd6-9833-1e65670d8556","order_by":2,"name":"Haixia Tu","email":"","orcid":"","institution":"Beijing Fengtai You’anmen Hospital","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Haixia","middleName":"","lastName":"Tu","suffix":""},{"id":186015126,"identity":"dd312263-f011-4141-86c7-899fa66c7433","order_by":3,"name":"Haitao Zhu","email":"","orcid":"","institution":"Beijing Fengtai You’anmen Hospital","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Haitao","middleName":"","lastName":"Zhu","suffix":""},{"id":186015127,"identity":"8c0c0081-51be-4fdf-8c95-218cb84c6b10","order_by":4,"name":"Zhen Guo","email":"","orcid":"","institution":"Beijing Fengtai You’anmen Hospital","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Zhen","middleName":"","lastName":"Guo","suffix":""},{"id":239411984,"identity":"3c9d817c-b3ba-43d5-9ff3-e2750d6b7cd3","order_by":5,"name":"Lianrui Guo","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA9klEQVRIiWNgGAWjYBACPmYwJQEiGB8kVNTIsbG3H8CrhQ1JC7PBhzPHjPl4ziTg14LMlpzZxpw4T8LBAL8WduZnjyvbLBjkI5IPSPOwsaW3STAkMPyo2IbHYWzmhmeBygxvpCUY8/DI5LZJNx5g7DlzG59fzCQbQVpm5Bgk80iw5bbJHEhgZmzDp4X9G1zLYR4D5nQ2iQQDAlp4ILbIS+QYNs5IYE4gRkuZZMM5CQYDnmfJDB8OHDNsAwbyQXx+4ec/vk2yoayOQb49+fiPxH818vLt7Qcf/KjArQUG6jccQOIdwKEKFcg3EKVsFIyCUTAKRiIAAJBWS4xy4dG5AAAAAElFTkSuQmCC","orcid":"","institution":"Xuanwu Hospital Capital Medical University","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Lianrui","middleName":"","lastName":"Guo","suffix":""}],"badges":[],"createdAt":"2023-03-17 04:44:22","currentVersionCode":2,"declarations":"","doi":"10.21203/rs.3.rs-2703023/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-2703023/v2","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.17305/bb.2023.9831","type":"published","date":"2023-10-21T17:08:29+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":44467530,"identity":"f48864f4-2355-483e-8d60-75cedfd33c58","added_by":"auto","created_at":"2023-10-11 21:47:38","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":74060,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eConstituent ratios of each clinical manifestation variable. \u003c/strong\u003eThe numbers of patient were labelled in the figure.\u003c/p\u003e","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-2703023/v2/393bc722c9771bad70663332.png"},{"id":44467532,"identity":"38a8c61d-2142-4440-9535-af5959f8ce35","added_by":"auto","created_at":"2023-10-11 21:47:38","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":83315,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eConstituent ratios of each diagnostic variable. \u003c/strong\u003eThe numbers of patient were labelled in the figure. CT: computed tomography; PA: percutaneous aortogram; SO: surgical operation; DUS: doppler ultrasound; MR: magnetic resonance.\u003c/p\u003e","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-2703023/v2/af5a79c6be2a1db53cd3df7f.png"},{"id":44467662,"identity":"fdb6afb1-842b-46a2-93a3-23a6f555a9af","added_by":"auto","created_at":"2023-10-11 21:55:38","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":41046,"visible":true,"origin":"","legend":"\u003cp\u003e\u003cstrong\u003eConstituent ratios for each treatment and outcome variable. \u003c/strong\u003eThe numbers of patient were labelled in the figure. PS: primary surgery; PEVT: primary endovascular therapy; CO: conservative observation; SEVT: secondary endovascular therapy; SS: secondary surgery.\u003c/p\u003e","description":"","filename":"3.png","url":"https://assets-eu.researchsquare.com/files/rs-2703023/v2/bc5b601fea5b474c151329cb.png"},{"id":55033245,"identity":"5e6b1c65-b061-4121-8e93-2d0cde0a0f5e","added_by":"auto","created_at":"2024-04-20 17:08:40","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":668225,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-2703023/v2/1242db92-3ba0-421e-8a48-f46468b942f0.pdf"},{"id":44467533,"identity":"a383ba17-6e21-47cb-9e4c-392dbb09fe0c","added_by":"auto","created_at":"2023-10-11 21:47:38","extension":"docx","order_by":4,"title":"","display":"","copyAsset":false,"role":"supplement","size":2030910,"visible":true,"origin":"","legend":"","description":"","filename":"SUPPLEMENTALDATA.docx","url":"https://assets-eu.researchsquare.com/files/rs-2703023/v2/f75a94bd68d93b32c1410254.docx"}],"financialInterests":"No competing interests reported.","formattedTitle":"\u003cp\u003eA systematic review of blunt abdominal aortic injury and analysis of predictors for death\u003c/p\u003e","fulltext":[{"header":"Introduction","content":"\u003cp\u003eBlunt abdominal aortic injury (BAAI) is believed to be caused by the injury to the aorta relates to the blunt biomechanical direct and indirect forces incurred on the abdominal aorta, which is tethered between the spinal column and the peritoneum and abdominal viscera [1]. It is rare both in adults and children [2]. According to previous studies, it represented only 4-6% of total aortic injuries and less than 1% of total blunt trauma [3-5]. Although uncommon, it is lethal. A high but variable mortality with published rates ranging from 17% to 92% was demonstrated by previous studies [5-8]. Compared with blunt thoracic aortic injury (BTAI), BAAI is much less common. This is thought to be due, in part, to the relatively fixed position of the entire length of the abdominal aorta compared with the thoracic aorta\u0026rsquo;s fixation only at the ligamentum arteriosum, and base of the heart [9].\u003c/p\u003e\n\u003cp\u003eFor ease of exposure and repair at the time of surgery, Shalhub et al. divided all aortic lesion locations into 3 types [1]. This classification method was favoured by many researchers [10,\u0026nbsp;11]. On the other hand, for BTAI or nonspecific blunt aortic injury (BAI), researchers have developed many grading criteria for the severity of aortic lesions according to the pathological changes of injured aorta [12-15]. However, there are few studies on the effect of aortic lesion location and severity on the prognosis of BAAI patients. The therapeutic methods of BAAI mainly consisted of operation and conservative observation. Kondo et al. reported that the 24-h mortality and the hospital mortality of BAAI did not differ statistically among the various treatment modalities [16]. However, Sheehan et al. showed that patients who underwent aortic surgery had a statistically lower mortality than those who had not [17]. Other studies in this area are very few.\u003c/p\u003e\n\u003cp\u003eThe only few previous studies did not address much of the core knowledge about BAAI, which makes us poorly understood about this dangerous traumatic disease. So, we conducted this worldwide systematic review. It was registered with PROSPERO (CRD42023408842) within accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework [18].\u003c/p\u003e"},{"header":"Materials And Methods","content":"\u003ch2\u003eEthical statement\u003c/h2\u003e\n\u003cp\u003eAs this is a review based on published literatures and does not contain any individual identification information, ethical approval and consents to participate are not required, which is in line with local regulations and policies. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013).\u003c/p\u003e\n\u003ch2\u003eSearch strategy\u003c/h2\u003e\n\u003cp\u003eA systematic search in the Excerpta Medica Database, PubMed, Web of Science, and Cochrane Library was performed on December 23, 2022. All words synonymous with or similar to \u0026ldquo;abdominal aortic injury\u0026rdquo; were searched to eliminate omissions. The full search strategy is showed in Supplemental File 1.\u003c/p\u003e\n\u003ch2\u003eStudy selection\u003c/h2\u003e\n\u003cp\u003eThe abdominal aorta was defined as the aorta from the diaphragm to the bifurcation into the right and left common iliac arteries. The samples were set as human individuals with BAAI who suffered any kinds of injury on abdominal aorta due to blunt or non-piercing external force causes. All brief information of the searched articles was imported into Endnote X9 for duplicate removal and brief review. Then, the full texts of all available articles that passed the preliminary screening were downloaded and reviewed to identify those that were finally included in the study.\u003c/p\u003e\n\u003cp\u003eThe available ones from articles about abdominal aortic injury (AAI) obtained through primary search were all selected initially. And then, not limited by study design, any literature that reported individual data on BAAI patient could be included, allowing for missing values on variable. The exclusion criteria included (1) samples with concomitant thoracic aortic injury; (2) samples with pre-existing dilative aortic disease (such as aortic aneurysm) or aortic injury; (3) samples suspected of duplication; (4) articles which were published in non-English. If some of the BAAI samples reported in a certain article met the above selection criteria, they would be selected for inclusion in the presented review. Two authors (ML and CW) independently performed the data selection separately. Any discrepancies were resolved by consensus.\u003c/p\u003e\n\u003ch2\u003eData extraction\u003c/h2\u003e\n\u003cp\u003eMultiple variables of BAAIs as detailed as possible were set up for data extraction. The definitions and descriptions of each variable are shown in Supplemental File 2. Specifically, the \u0026ldquo;death after BAAI\u0026rdquo; was defined as any death due to the initial traumatic cause but excluding other causes such as a malignant cancer. The locations of aortic lesions were divided into 3 location zones [zone I (the zone from diaphragmatic hiatus to superior mesenteric artery (SMA), II (the zone including SMA and renal arteries), and III (the zone from infrarenal aorta to aortic bifurcation)] according to the method of Shalhub et al. [1]; and the injury severities of aortic lesions were divided into 5 grades {grade A (intimal tear or intramural hematoma), B [small pseudoaneurysm (less than 50% circumference)], C [large pseudoaneurysm (more than 50% circumference)], D (intraluminal truncation), and E (rupture)} further on the basis of Rabin et al.\u0026rsquo;s method [15]. Data extraction was performed by a pair of independent authors (HT and HZ). If, according to our definitions, the value (or classification) of a variable in an included article was not directly reported, these two authors will make independent judgments based on the description in the original text. Any queries and discrepancies were resolved through further discussion to reach a consensus.\u003c/p\u003e\n\u003ch2\u003eQuality assessment\u003c/h2\u003e\n\u003cp\u003eThe original studies were assessed by the Joanna Briggs Institute (JBI) checklist for case reports [19]. This tool includes 8 items, which evaluate whether the descriptions of the clinical characteristics, diagnosis, treatment, outcome, and other aspects on the patients in every report are comprehensive and clear. The item is scored 1 point if answer \u0026ldquo;yes\u0026rdquo; or \u0026ldquo;not applicable\u0026rdquo; and scored 0 point if answer \u0026ldquo;no\u0026rdquo; or \u0026ldquo;not clear\u0026rdquo;. If multiple cases were reported separately by some study, they would be evaluated separately, and the score of the whole study would take the lowest value of those of the cases.\u003c/p\u003e\n\u003cp\u003eAll included studies were classified as having \u0026ldquo;low\u0026rdquo; (0-3 points), \u0026ldquo;medium\u0026rdquo; (4-6 points), or \u0026ldquo;high\u0026rdquo; (7-8 points) methodological quality. Three independent authors (ML, ZG and LG) each finished quality assessments for all included articles. If opinions differed, the lower score was taken.\u003c/p\u003e\n\u003ch2\u003eStatistical analysis\u003c/h2\u003e\n\u003cp\u003eContinuous variables were presented as \u0026ldquo;mean \u0026plusmn; standard deviation\u0026rdquo; or \u0026ldquo;median with interquartile range (IQR)\u0026rdquo;, and categorical ones were presented as \u0026ldquo;number with percentage\u0026rdquo;. Statistical analyses were conducted using the Stata version 16.0 software (StataCorp., College Station, TX, USA). All hypothesis tests were two-sided, and \u003cem\u003eP\u003c/em\u003e \u0026lt;0.05 was considered to indicate a statistical difference. The age distributions of BAAI patients between genders were compared, using the Mann Whitney U test [20]. The constituent ratios of all samples in categorical variables were also calculated separately. The details of patients who died after BAAI were also described.\u003c/p\u003e\n\u003cp\u003eSetting the binary \u0026ldquo;death after BAAI\u0026rdquo; as outcome variable, the potential predictors were explored. Except obviously unrelated ones such as \u0026ldquo;diagnostic method\u0026rdquo;, all variables were entered into a binomial family generalized linear model (GLM) (link: log; standard error type: default; optimization method: maximum likelihood estimation) one by one for univariate regression analyses, using the relative risk (RR) with 95% confidence interval (CI) as measure [21]. To obtain a likely positive outcome while retaining as much detail as possible for categories, we tried multiple combinatorial modalities of core treatments and substituted the derived variables into the model separately. Then we attempted to simultaneously bring the obtained variables with \u003cem\u003eP\u003c/em\u003e value \u0026lt;0.20 into the above GLM for adjusted multivariate regression analysis. But the model failed to converge and could not derive a result. So, a multivariate regression analysis of these variables using a robust Poisson family GLM (link: log; standard error type: robust; optimization method: maximum likelihood estimation) was performed. Only those variables with a \u003cem\u003eP\u003c/em\u003e value \u0026lt;0.05 and an absolute RR value \u0026lt;1000 were accepted and considered as predictor. To assess the fitting ability, we also recorded the value of Akaike information criterion (AIC) [22] and log pseudolikelihood [23] of the final adopted regression model. Additionally, using Fisher\u0026rsquo;s exact test [24], patients with the calculated predictors were selected for subgroup analyses, to explore the influences of different treatment modalities on mortality in these specific patients. All statistical analyses were conducted by ML.\u003c/p\u003e"},{"header":"Results","content":"\u003ch2\u003eCharacteristics of studies and patients\u003c/h2\u003e\n\u003cp\u003eThe systematic search yielded a total of 2,099 articles before 1,123 duplicates were removed, following which 766 ones were excluded after title abstract sieve. Finally, 103 articles were included after full text assessment [25-127] (Supplemental File 3).\u003c/p\u003e\n\u003cp\u003eThese articles included 102 case reports and 1 conference abstract. Of them, there were 14 (13.6%) ones which included multiple (2 to 7) cases. After quality assessment, there were 91 high-quality studies (88.3%), 12 medium-quality ones (11.6%), and no low-quality ones. All they were published from 1961 to 2021, of which 83 (80.6%) were published after 1990. And there were 25 reporting countries, with USA reporting the most frequently (48, 46.6%). One patient was injured abroad but went to USA later for treatment and was reported by American doctors [31]; the remaining patients were considered to have been injured and treated (if happened) in the reporting country. The authors of one article published in 2018 were from Serbia and Montenegro respectively [98], and the reporting country of this article was considered to be one rather than two. A total of 133 BAAI patients at a median age of 34 (IQR, 17-54) (ranged from 1 to 89) were included. The detailed characteristics of the included studies and patients are shown in Supplemental File 4. Among the patients, there were 35 females (26.3%), who were generally older than males (\u003cem\u003eP\u003c/em\u003e = 0.012) (Supplemental File 5).\u003c/p\u003e\n\u003ch2\u003eClinical manifestations, diagnoses, treatments, and outcomes\u003c/h2\u003e\n\u003cp\u003eThe most common injury way of BAAI patients was the \u0026ldquo;direct strike (non seat belt)\u0026rdquo; (collision, fall, gas shock, etc.), accounting for 53.4%. The various clinical presentations of all patients were\u0026nbsp;classified\u0026nbsp;into 4 categories, with pain being the most common (65.5%). In addition, 5.0% of patients presented with cardiopulmonary arrest and 36.4% with shock. And taking the first day after trauma as the boundary, 11.8% of patients experienced delayed manifestations, while 4.2% had no acute manifestations. The constituent ratios of clinical manifestation variables are shown in Figure 1.\u003c/p\u003e\n\u003cp\u003eThe most common diagnostic method was computed tomography (CT), accounting for 52.6%. Three patients were not diagnosed with BAAI until 7 months, 8 years, and 9 years after trauma respectively due to different reasons [41,\u0026nbsp;43,\u0026nbsp;58]. According to the established classifications, 88.3% of patients had an aortic lesion located in zone III, and 47.0% were grade A severity. Thrombosis at the aortic lesion was reported in 28.8%, and 78.3% were reported to have aortic degeneration. In addition, 66.9% of patients were injured to other organs in abdomen, 25.6% were injured to lumbar spine, and 23.3% were injured to other parts of body. Concomitant injuries up to 7 organs or tissues after trauma was reported in one patient [102]. Among all injured organs in abdomen, the gastrointestinal tract was the most common, accounting for 49.6% of all 133 BAAI patients.\u0026nbsp;The constituent ratios of diagnosis variables are shown in\u0026nbsp;Figure\u0026nbsp;2.\u003c/p\u003e\n\u003cp\u003eThe most common treatment modality was primary open surgery (OS, 55.2%), followed by primary endovascular therapy (EVT, 24.0%) and others. One patient underwent percutaneous aortic stent implantation after failed conservative observation, but it was found intraoperatively that the stent migrated to suprarenal aorta, so he underwent open aorto-aortic bypass and recovered well [91]. He was considered to have received a secondary OS as the core treatment modality. Among the 114 patients who underwent operation treatment, the choice of their approach (OS or percutaneous EVT) was not statistically associated with the presence of neither injuries to organs in abdomen, to lumbar spine, or to other parts of body (\u003cem\u003eP\u003c/em\u003e = 0.144, 0.240, and 0.486, respectively). The same situation also arised whether the gastrointestinal tract which was the most representative abdominal organ, was injured, i.e., of the 114 patients who underwent operations, 60 had gastrointestinal injury, and 29 of them underwent OS rather than EVT (\u003cem\u003eP\u003c/em\u003e \u0026gt;0.999). After categorizing the timing of core treatment after injury, it was found that most patients were treated rapidly (within 3 days after injury) (64.5%). One patient received OS immediately after reception [43], whereas another patient was not treated until 9th year after injury because of a missed diagnosis [44]. The longest follow-up was 10 years [105]. 27.1% of patients had various non-fatal adverse events after treatment, of which acute renal failure was most common (47.8%). Some patients had up to 4 kinds of adverse events after OS, excluding multiple organ dysfunction syndrome [43,\u0026nbsp;45]. 5.0% and 10.0% of patients had residual chronic lower limb ischemia and neurological dysfunction as sequelae after treatment respectively. Finally, it was found that 19 patients (15.3%) died after BAAI. They were classified according to the time of death (Table 1). The constituent ratios of treatment and outcome variables are shown in Figure 3. Among the 53 cases with available data who had gastrointestinal injury and underwent operations, 3 died after BAAI in the OS group and none in the EVT group, which did not suggest a statistical difference (\u003cem\u003eP\u003c/em\u003e = 0.543).\u003c/p\u003e\n\u003ch2\u003eDeath after BAAI\u003c/h2\u003e\n\u003cp\u003eDue to failed convergence of the binomial regression model after selecting variables through univariate analyses, a robust Poisson GLM was taken for analysis and then derived several variables with \u003cem\u003eP\u003c/em\u003e \u0026lt;0.05. However, the absolute RR values of some of these variables (including all the multiple categorical ones) are very exaggerated exceeding 1000, even reaching trillions. Therefore, multiple stepwise regression approaches (forward, backward, etc.) were taken in an attempt to find variables that destabilized the model. Then, a stable Poisson regression model with 86 observations included was obtained after excluding all multiple categorical variables. The AIC value of this model was 1.018, and the log pseudolikelihood value was -34.776. We collected all the variables in this model and tried the binomial regression again, but still failed in convergence. So, the Poisson regression model was adopted finally, and 3 statistically significant predictors (i.e. risk factors) for death after BAAI were obtained, which were lower limb ischemia (RR, 7.137; 95% CI, 1.154-44.161; \u003cem\u003eP\u003c/em\u003e = 0.035), cardiopulmonary arrest (RR, 10.250; 95% CI, 1.452-72.344; \u003cem\u003eP\u003c/em\u003e = 0.020), and injuries to other parts of body (RR, 2.593; 95% CI, 1.189-5.655; \u003cem\u003eP\u003c/em\u003e = 0.017). The analysis details are shown in Table 2, and the adopted model results are also presented in a forest plot (Supplemental File 6).\u003c/p\u003e\n\u003cp\u003eAfter subgroup analyses, it was found that the mortality of BAAI patients with lower limb ischemia or injuries to other parts of body, whether undergoing primary operation or secondary operation, was lower than that of those who received conservative observation (\u003cem\u003eP\u003c/em\u003e = 0.020 and 0.035 respectively); however, the mortalities with cardiopulmonary arrest did not differ significantly among different treatment modalities (\u003cem\u003eP\u003c/em\u003e \u0026gt;0.999). The details are shown in Supplemental File 7.\u003c/p\u003e"},{"header":"Discussion","content":"\u003ch2\u003eSignificance of this study\u003c/h2\u003e\n\u003cp\u003eIn this review, the multifaceted characteristics of BAAIs and risk factors for death were revealed. This can help clinicians to better recognize this rare but fatal traumatic disease and to take more timely and accurate treatment for high-risk patients.\u003c/p\u003e\n\u003ch2\u003eCharacteristics of BAAIs\u003c/h2\u003e\n\u003cp\u003eMost studies on BAAI\u0026nbsp;were all\u0026nbsp;case reports, showing the scarcity of BAAI. Among the 133 included BAAI patients, the median age of males was significantly lower than that of females (32 vs. 45, \u003cem\u003eP\u003c/em\u003e = 0.012). The reason may be that men in adolescence or youth prefer to be exposed to intense activities, such as driving motor vehicles, playing football, boxing.\u003c/p\u003e\n\u003cp\u003eA direct blunt external force of sufficient magnitude can cause BAAI, and this type of trauma accounted for the majority (53.4%) in this review. While the proportion of patients who did not have a direct crash but were restricted by the seat belt and thereby developed a BAAI also reached 43.1%. We have recognized that the mechanism caused by these injury modalities is the combined compressive effect on the abdominal aorta (AA) by the anteriorly located abdominal viscera and the posteriorly located lumbar spine, associated with sudden deceleration [99,\u0026nbsp;128]. Meanwhile, we also found 4 (3.4%) patients who did not suffer any direct external force applied to abdomen, and their cause of injury was classified as back hyperextension that caused excessive traction on AA [82,\u0026nbsp;83,\u0026nbsp;88,\u0026nbsp;100]. Additionally, regardless of the injury way, damage to the lumbar spine may promote the development of BAAI due to the increased local force to AA [46,\u0026nbsp;47,\u0026nbsp;82]. The\u0026nbsp;presented\u0026nbsp;review shows that the clinical manifestations of BAAI patients are diverse. In addition to shock and cardiopulmonary arrest in severe cases, pain, lower limb ischemia, and neurological dysfunction were representative. Among them, the proportion of patients with pain in abdomen, chest, back, or lumbar flakes reached 65.5%, suggesting that pain may be the most common clinical symptom of BAAI patients. In addition to pain and lower limb ischemia due to reduced blood flow, we also found that 12.6% of patients had neurological dysfunctions\u0026nbsp;with\u0026nbsp;different degrees, such as paraplegia, hypoesthesia, asynodia and so on. The reason may be the direct injury of the lumbosacral spinal cord or plexus, or the damage of Adamkiewicz artery originating from AA and supplying blood directly to the lumbosacral spinal cord [129].\u003c/p\u003e\n\u003cp\u003eThe majority (52.6%) of BAAIs were diagnosed by CT. It shows that CT has become the most important imaging examination for the diagnosis of BAAI, which is also in line with the views of many researchers [10,\u0026nbsp;130]. Up to 88.3% of patients\u0026rsquo; aortic lesions were in zone III which is from infrarenal aorta to the aortic bifurcation. However, there were only 15 cases of injury located in zone I (supra-SMA) and zone II (SMA to renal arteries). The reason may be that infrarenal AA is less protected compared with suprarenal AA [131]. Meanwhile, after regression analyses, there was not enough evidence to prove that different injury locations affected the mortality rate of BAAI. Severity grading criteria for aortic lesion have not been uniform [10,\u0026nbsp;15,\u0026nbsp;132]. After comparison, we referred to Rabin et al.\u0026rsquo;s method on BAI [15]. However, intimal tears belong to the mildest grade (grade A) by this grading standard, but apparently the large aortic dissections (ADs) with or without thrombosis leading to luminal obstruction cannot meet any grade including A. So, we add this severe AD as the grade D which was only milder to grade E (rupture) on the basis of this standard. Then we found that even so, the proportion of BAAI patients of the mildest grade A remained the highest (47.0%). This suggests that most BAAI patients have a mild damage on AA. Aortic degenerative pathology was present in 78.3% of patients and lumbar spine fractures in 25.6% with relevant reports. These two conditions may increase the susceptibility of trauma patients to BAAI based on the pathogenic mechanism theory that AA is compressed, and this is also in line with the ideas in several studies [18,\u0026nbsp;131].\u003c/p\u003e\n\u003cp\u003eThe treatment of choice for BAAI patients by most clinicians was primary OS (55.2%), and the proportion of primary operation including primary EVT had even reached 79.2%. This suggests that the application of conservative treatment in BAAI is still limited. However, not all BAAI patients face the same risks obviously. Shalhub et al. believed that whether\u0026nbsp;operation\u0026nbsp;should be performed and which operation modality should be chosen depend on the location and severity of the aortic injury [1,\u0026nbsp;6]. Additionally, the results of this presented review suggest that clinicians\u0026rsquo; choices of operation modality were not related to the presence of injuries to other tissues or organs (especially those in abdomen). We believe that part of the reason for this is the habits and preferences of various medical centers and clinicians.\u003c/p\u003e\n\u003cp\u003eGenerally, the causes of some unwanted or unexpected events in BAAIs could not be explained as traumatic or iatrogenic alone. So we collectively referred to these negative events after treatment (including conservative observation) as \u0026ldquo;adverse events\u0026rdquo; (excluding death). And we found that its proportion was 27.1%, which was similar to a previous study [17]. After excluding deaths that were apparently unrelated to BAAI (such as malignancies years later), the mortality after BAAI in the presented review was 15.3% (n = 19). The immediate cause of death in these patients was mostly haemorrhage after AA injury, even after treatments.\u003c/p\u003e\n\u003ch2\u003ePredictors for death after BAAI\u003c/h2\u003e\n\u003cp\u003eThe analysis results show that, the risk of death after BAAI is increased in patients with lower limb ischemia, cardiopulmonary arrest, or injuries to other parts of body. We believe that only severe AA injuries such as grade D/E are sufficient to cause lower extremity ischemic symptoms. So, the variable of lower limb ischemia can directly reflect the severity of ischemia caused by aortic injury. And acute limb ischemia is associated with many serious consequences including death, which has long been proved\u0026nbsp;[133,\u0026nbsp;134]. The preliminary multivariable model did show that the severity of aortic disease (multiple categorical variable) directly influenced the mortality (\u003cem\u003eP\u003c/em\u003e \u0026lt;0.001), but it was not adopted because of unusual RR values (over 1000). On the other hand, cardiopulmonary arrest and injuries to other parts of body both mean the severity of trauma to the whole body, not just to AA. In other words, other simultaneous injuries may also lead to death or aggravate the impact of AA injury on the body. It is very difficult to explore the specific initial cause of death of a patient with multiple injuries. Additionally, we also removed some variables because of their exceeded 1000 RR values. For example, the mortalities of zone I and II injuries that were more difficult to be exposed or controlled by OS were higher than that of zone III injuries, secondary EVT after failed conservative observation was associated with higher mortality than conservative treatment throughout, and so on. They should not be easily negated although not proven to be statistically valuable, because of the theoretical plausibility. The reason for the unusual RR values estimated is the small available sample size, likely. We look forward to more studies with large sample sizes.\u003c/p\u003e\n\u003cp\u003eResults of subgroup analyses suggest that, compared with conservative observation, both primary and secondary operation treatment (including OS and EVT) for BAAI patients with lower limb ischemia or injuries to other parts of body can reduce the risk of death (\u003cem\u003eP\u003c/em\u003e \u0026lt;0.05). This proves the importance of operation treatment for the BAAI patients at high-risk. Meanwhile, the differences in protective effects between the three treatment modalities are not reflected among BAAI patients with cardiopulmonary arrest. Also due to the small sample size (n = 2 for this subgroup), we cannot easily make a conclusion that operation cannot play a role in reducing the risk of death in such BAAI patients.\u003c/p\u003e\n\u003ch2\u003eLimitations\u003c/h2\u003e\n\u003cp\u003eThis review also has some limitations. First, since there were no uniform standards among the references, the descriptions of the variables were sometimes vague, affecting the accuracy of data extraction and analysis. Second, cases with good curative effect might be easier to be reported and published, while those that have unsatisfactory outcomes for various reasons might not. This may make the true mortality underestimate, increasing the publication bias.\u003c/p\u003e"},{"header":"Conclusions","content":"\u003cp\u003eBAAI is a lethal injury with diverse characteristics and a mortality rate of 15.3% at least. The increased mortality risk of BAAI is associated with lower limb ischemia, cardiopulmonary arrest, and injuries to other parts (other than abdomen and lumbar spine) of body. Operation (including OS and EVT) can reduce the mortality of BAAI patients with lower limb ischemia or injuries to other parts of body, even as a salvage measure after failure of conservative observation.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003eACKNOWLEDGMENTS\u003c/p\u003e\n\u003cp\u003eNone.\u003c/p\u003e\n\u003cp\u003eConflicts of interest:\u0026nbsp;Authors declare no conflicts of interest.\u003c/p\u003e\n\u003cp\u003eFunding:\u0026nbsp;Authors received no specific funding for this work.\u003c/p\u003e\n\u003cp\u003eData availability: The original data is available from the corresponding author on reasonable request.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n \u003cli\u003eShalhub S, Starnes BW, Tran NT, Hatsukami TS, Lundgren RS, Davis CW, et al. Blunt abdominal aortic injury. J Vasc Surg 2012;55(5):1277-85.\u003c/li\u003e\n \u003cli\u003eSadaghianloo N, Jean-Baptiste E, Breaud J, Declemy S, Kurzenne JY, Hassen-Khodja R. 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Vasc Surg 2001;35(5):385-9.\u003c/li\u003e\n \u003cli\u003eStahlfeld KR, Mitchell J, Sherman H. Endovascular repair of blunt abdominal aortic injury: case report. J Trauma 2004;57(3):638-41.\u003c/li\u003e\n \u003cli\u003eTeruya TH, Bianchi C, Abou-Zamzam AM, Ballard JL. Endovascular treatment of a blunt traumatic abdominal aortic injury with a commercially available stent graft. Ann Vasc Surg 2005;19(4):474-8.\u003c/li\u003e\n \u003cli\u003eIdoguchi K, Yamaguchi M, Okada T, Nomura Y, Sugimura K, Okita Y, et al. Endovascular treatment of blunt traumatic abdominal aortic occlusion with kissing stent placement. Cardiovasc Intervent Radiol 2012;35(5):1216-20.\u003c/li\u003e\n \u003cli\u003eal Zahrani HA. False aneurysm of the abdominal aorta after blunt trauma. Eur J Vasc Surg 1991;5(6):685-7.\u003c/li\u003e\n \u003cli\u003eSethi GK, Scott SM, Takaro T. False aneurysm of the abdominal aorta due to blunt trauma. Ann Surg 1975;182(1):33-6.\u003c/li\u003e\n \u003cli\u003eAlmeida AA, Frydman GM, Walker PJ. Hyperextension injury causing abdominal aortic rupture. Eur J Vasc Endovasc Surg 1997;13(2):247-8.\u003c/li\u003e\n \u003cli\u003eKalina M, Donovan M, Giberson F, Tinkoff G. Inframesocolic Abdominal Aortic Injury and Lumbar Vertebral Body Fracture Secondary to Hyperextension with Blunt Trauma. Eur J Trauma Emerg Surg 2010;36(1):67-9.\u003c/li\u003e\n \u003cli\u003eCoimbra R, Yang J, Hoyt DB. Injuries of the abdominal aorta and inferior vena cava in association with thoracolumbar fractures: a lethal combination. J Trauma 1996;41(3):533-5.\u003c/li\u003e\n \u003cli\u003eMarty-An\u0026eacute; CH, Alric P, Prudhomme M, Chircop R, Serres-Cousin\u0026eacute; O, Mary H. Intravascular stenting of traumatic abdominal aortic dissection. J Vasc Surg 1996;23(1):156-61.\u003c/li\u003e\n \u003cli\u003eRaguan B, Shnaker A, Fajer S. Isolated Abdominal Injury of Blunt Aortic Trauma: Two Case Reports and Review of the Literature. Journal of Endovascular Resuscitation and Trauma Management 2018;2(3):123-6.\u003c/li\u003e\n \u003cli\u003eKhattak MN, Olivero EV, Curi MA, Dhadwal AK, Padberg FT, Huang JT. Isolated blunt abdominal aortic injury without concomitant abdominal injuries treated with endovascular stent grafting. J Vasc Surg Cases 2015;1(4):258-60.\u003c/li\u003e\n \u003cli\u003eDudko S, Kusz D, Ziaja D, Kusz B. Laceration of abdominal aorta by a fragment of fractured L2 vertebral body after a low-energy injury: a case report and review of literature. Spine 2012;37(22):e1406-9.\u003c/li\u003e\n \u003cli\u003eKhanna PC, Rothenbach P, Guzzetta PC, Bulas DI. Lap-belt syndrome: management of aortic intimal dissection in a 7-year-old child with a constellation of injuries. Pediatr Radiol 2007;37(1):87-90.\u003c/li\u003e\n \u003cli\u003eVuorisalo S, Railo M, Lappalainen K, Aho P, Lep\u0026auml;ntalo M. Low-energy blunt abdominal aortic trauma in an underweighted man. Eur J Vasc Endovasc Surg 2005;29(6):595-6.\u003c/li\u003e\n \u003cli\u003eDiez AA, Monteiro EM, Hoyos YG, Legrand JL. Management and Evolution of a Wallstent Migration in a Pediatric Blunt Traumatic Abdominal Aortic Injury. Ann Vasc Surg 2018;47:281.e15-9.\u003c/li\u003e\n \u003cli\u003eParrish DW, Barnhorst A, Trebska-McGowan K, Amendola M, Haynes JH. Nonoperative management of pediatric aortic injury with seat belt syndrome. Ann Vasc Surg 2015;29(6):1316.e1-6.\u003c/li\u003e\n \u003cli\u003eMacbeth A, Malone JM, Norton LW, Peltier LF. Paralysis and aortic thrombosis following blunt abdominal trauma. J Trauma 1982;22(7):591-4.\u003c/li\u003e\n \u003cli\u003eNishimura K, Kanaoka Y, Ikebuchi M, Hiroe T, Tachibana M, Ishiguro S, et al. Percutaneous balloon fenestration in a case of traumatic abdominal aortic dissection with lower extremity ischemia. J Vasc Surg 2000;32(3):616-8.\u003c/li\u003e\n \u003cli\u003eBalas P, Stamatopoulos C, Chagitheophilou C. Post-traumatic aneurysm of the abdominal aorta. Angiology 1974;25(5):360-3.\u003c/li\u003e\n \u003cli\u003eFreni L, Barbetta I, Mazzaccaro D, Settembrini AM, Dallatana R, Tassinari L, et al. Seat belt injuries of the abdominal aorta in adults\u0026ndash;case report and literature review. Vasc Endovascular Surg 2013;47(2):138-47.\u003c/li\u003e\n \u003cli\u003eShweiki E, Klena JW, Halm KA, Leonard DJ. Seat belt injury to the abdominal aorta. Am J Emerg Med 2000;18(2):236-7.\u003c/li\u003e\n \u003cli\u003eTomic I, Dragas M, Vasin D, Loncar Z, Fatic N, Davidovic L. Seat-Belt Abdominal Aortic Injury-Treatment Modalities. Ann Vasc Surg 2018;53:270.e1-6.\u003c/li\u003e\n \u003cli\u003eClyne CA, Ashbrooke EA. Seat-belt aorta: isolated abdominal aortic injury following blunt trauma. Br J Surg 1985;72(3):239.\u003c/li\u003e\n \u003cli\u003eWarrian RK, Shoenut JP, Iannicello CM, Sharma GP, Trenholm BG. Seatbelt injury to the abdominal aorta. J Trauma 1988;28(10):1505-7.\u003c/li\u003e\n \u003cli\u003eCampbell DK, Austin RF. Seat-belt injury: injury of the abdominal aorta. Radiology 1969;92(1):123-4.\u003c/li\u003e\n \u003cli\u003eDavid D, Blumenberg RM. Subintimal aortic dissection with occlusion after blunt abdominal trauma. Arch Surg 1970;100(3):302-4.\u003c/li\u003e\n \u003cli\u003eCrabb GM, McQuillen KK. Subtle abdominal aortic injury after blunt chest trauma. J Emerg Med 2006;31(1):29-31.\u003c/li\u003e\n \u003cli\u003eHuh U, Lee CW, Kim SH, Park CI, Chung SW, Song S, et al. Successful Treatment Using a Kissing Stent for Blunt Abdominal Aortic Injury: A Case Report. Cardiovasc Intervent Radiol 2018;41(6):972-5.\u003c/li\u003e\n \u003cli\u003eNicholls S, Karmy-Jones R. Ten-year follow-up after endovascular repair of traumatic abdominal aortic rupture. Innovations (Phila) 2011;6(1):51-3.\u003c/li\u003e\n \u003cli\u003eQureshi A, Roberts N, Nicholson A, Johnson B. Three-dimensional reconstruction by spiral computed tomography to locate aortic tear following blunt abdominal trauma. Eur J Vasc Endovasc Surg 1997;14(4):316-7.\u003c/li\u003e\n \u003cli\u003eBorja AR, Lansing AM. Thrombosis of the abdominal aorta caused by blunt trauma. J Trauma 1970;10(6):499-501.\u003c/li\u003e\n \u003cli\u003eHeck JM, Bittles MA. Traumatic abdominal aortic dissection in a 16-month-old child. Pediatr Radiol 2009;39(7):750-3.\u003c/li\u003e\n \u003cli\u003eYulevich A, Singer-Jordan J, Grozovsky Y, Zonis Z, Sweed Y. Traumatic abdominal aortic dissection in a child. J Trauma 2007;62(4):1039-41.\u003c/li\u003e\n \u003cli\u003eGunn M, Campbell M, Hoffer EK. Traumatic abdominal aortic injury treated by endovascular stent placement. Emerg Radiol 2007;13(6):329-31.\u003c/li\u003e\n \u003cli\u003eThal ER, Perry MO, Crighton J. Traumatic abdominal aortic occlusion. South Med J 1971;64(6):653-6.\u003c/li\u003e\n \u003cli\u003eAndrey V, Bettschart V, Ducrey N, Constantin C, Genin B. Traumatic abdominal aortic rupture treated by endovascular stent placement in an 11-year-old boy. Journal of Pediatric Surgery Case Reports 2013;1(4):56-9.\u003c/li\u003e\n \u003cli\u003eMatolo NM, Danto LA, Wolfman EF. Traumatic aneurysm of the abdominal aorta. Report of two cases and review of the literature. Arch Surg 1974;108(6):867-9.\u003c/li\u003e\n \u003cli\u003eBoumzebra D, Ettaoumi Y, Yaacoubi M, Haddani J, Fehri M, Mehadji BA. Traumatic aneurysm of the bifurcation of the abdominal aorta in an infant. A case report. Eur J Pediatr Surg 2005;15(3):200-2.\u003c/li\u003e\n \u003cli\u003eAnomah Ngu V, Konstam PG. Traumatic dissecting aneurysm of the abdominal aorta. Br J Surg 1965;52(12):981-2.\u003c/li\u003e\n \u003cli\u003eDesai SC, Chute DJ, Desai BC, Koloski ER. Traumatic dissection and rupture of the abdominal aorta as a complication of the Heimlich maneuver. J Vasc Surg 2008;48(5):1325-7.\u003c/li\u003e\n \u003cli\u003eGordon CR, Eakins JS, DeAngelo FJ, Ross SE, Ierardi RP. Traumatic fall injury causing a displaced vertebral body fracture with concomitant abdominal aortic injury. J Trauma 2007;62(1):263.\u003c/li\u003e\n \u003cli\u003eBrunsting LA, Ouriel K. Traumatic fracture of the abdominal aorta. Rupture of a calcified abdominal aorta with minimal trauma. J Vasc Surg 1988;8(2):184-6.\u003c/li\u003e\n \u003cli\u003eAddicott B, Schmitz K. Traumatic handle bar injury with aortic disruption. Pediatric Radiology 2014;44(Suppl 1):S174.\u003c/li\u003e\n \u003cli\u003eGodry H, R\u0026ouml;lleke G, Mumme A, Schildhauer TA, Gothner M. Traumatic Infra-renal Aortic Dissection After a High-energy Trauma: A Case Report of a Primary Missed Diagnosis. Orthop Rev 2014;6(1):5031.\u003c/li\u003e\n \u003cli\u003eCoz S, Merson L, Morel N, Dabadie P. Traumatic rupture of the abdominal aorta after spinal fracture from low fall. Ann Fr Anesth Reanim 2010;29(9):658-60.\u003c/li\u003e\n \u003cli\u003eWalker AG, Walker RM. Traumatic thrombosis of the aorta. Br Med J 1961;1(5238):1514.\u003c/li\u003e\n \u003cli\u003eChiarini V, Coniglio C, Ferri E, Lupi C, Tugnoli G, Montanari N, et al. Use of REBOA as a Bridge to Endovascular Aortic Repair in Blunt Abdominal Aortic Injury. Journal of Endovascular Resuscitation and Trauma Management 2019;3(1):45-50.\u003c/li\u003e\n \u003cli\u003eAbed H, Ball WR, Stone T, Houghton A. Very late rupture of a post-traumatic abdominal aortic pseudoaneurysm. BMJ Case Rep. 2017;2017:bcr2016218356.\u003c/li\u003e\n \u003cli\u003eLock JS, Huffman AD, Johnson RC. Blunt trauma to the abdominal aorta. J Trauma 1987;27(6):674-7.\u003c/li\u003e\n \u003cli\u003eGilani R, Saucedo-Crespo H, Scott BG, Tsai PI, Wall MJ, Mattox KL. Endovascular therapy for overcoming challenges presented with blunt abdominal aortic injury. Vasc Endovascular Surg 2012;46(4):329-31.\u003c/li\u003e\n \u003cli\u003eJovanovic M, Radojkovic M, Djordjevic P, Rancic D, Jovanovic N, Rancic Z. Recycling and Reinforcing Intimomedial Flap of the Infrarenal Aorta Using Anterior Longitudinal Ligament in Patients With Acute Trauma With Bowel Injuries. Vasc Endovascular Surg 2017;51(7):501-5.\u003c/li\u003e\n \u003cli\u003eFeliciano DV. Abdominal vascular injuries. Surg Clin North Am 1988;68(4):741-55.\u003c/li\u003e\n \u003cli\u003eSzilagyi DE, Hageman JH, Smith RF, Elliott JP. Spinal cord damage in surgery of the abdominal aorta. Surgery 1978;83(1):38-56.\u003c/li\u003e\n \u003cli\u003eMellnick VM, McDowell C, Lubner M, Bhalla S, Menias CO. CT features of blunt abdominal aortic injury. Emerg Radiol 2012;19(4):301-7.\u003c/li\u003e\n \u003cli\u003eInaba K, Kirkpatrick AW, Finkelstein J, Murphy J, Brenneman FD, Boulanger BR, et al. Blunt abdominal aortic trauma in association with thoracolumbar spine fractures. Injury 2001;32(3):201-7.\u003c/li\u003e\n \u003cli\u003eHarris DG, Drucker CB, Brenner ML, Sarkar R, Narayan M, Crawford RS. Patterns and management of blunt abdominal aortic injury. Ann Vasc Surg 2013;27(8):1074-80.\u003c/li\u003e\n \u003cli\u003eMcNally MM, Univers J. Acute Limb Ischemia.\u0026nbsp;Surg Clin North Am\u0026nbsp;2018;98(5):1081-96.\u003c/li\u003e\n \u003cli\u003eHess CN, Huang Z, Patel MR, Baumgartner I, Berger JS, Blomster JI, et al. Acute Limb Ischemia in Peripheral Artery Disease. Circulation 2019;140(7):556-65. \u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp style='margin-top:.25in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:200%;font-size:24px;font-family:\"Times New Roman\",serif;color:#1F4E79;'\u003e\u003cstrong\u003e\u003cspan style='font-size:13px;line-height:200%;font-family:\"Times\",serif;'\u003eTable 1. \u0026nbsp;Data from 19 patients who died after BAAI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003ctable style=\"width: 6.4e+2pt;border-collapse: collapse;border:none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 78pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eDeath type\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003en((n/19)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026times;100%)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAge (y)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eGender\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eInjury way\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eClinical manifestations\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAortic lesion characteristics\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eOther injuries\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eCore treatment and it\u0026rsquo;s timing\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eTime to death after injury\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eImmediate cause of death\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAdverse events\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"5\" style=\"width: 78pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eBefore diagnosis\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"5\" style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e5 (26.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRaul et al. [\u003cspan style=\"color:blue;\"\u003e60\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e70\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCA, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E, T, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, LP, O\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRaul et al. [\u003cspan style=\"color:blue;\"\u003e60\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCA, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eG E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, LP, O\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRaul et al. [\u003cspan style=\"color:blue;\"\u003e60\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e19\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCA, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eG E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, O\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDavid et al. [\u003cspan style=\"color:blue;\"\u003e78\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e54\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ II, G A, T\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, O\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRespiratory failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDesai et al. [\u003cspan style=\"color:blue;\"\u003e92\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e78\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCA, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ II, G A, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 78pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eAfter diagnosis and before initial treatment\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1 (5.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHarkin et al. [\u003cspan style=\"color:blue;\"\u003e8\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e7\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 78pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDuring operation\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2 (10.5)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHewitt et al. [\u003cspan style=\"color:blue;\"\u003e12\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e65\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLLI, OM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G D, T, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eGordon et al. [\u003cspan style=\"color:blue;\"\u003e93\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e46\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCA, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ II, G E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLP\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSpinal cord injury\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"10\" style=\"width: 78pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eAfter initial treatment\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"10\" style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e10 (52.6)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eReisman et al. [\u003cspan style=\"color:blue;\"\u003e14\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e55\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI, ND, OM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E, T, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, O\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2mo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMODS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMODS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eBergqvist et al. [\u003cspan style=\"color:blue;\"\u003e19\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e66\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E, T, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e9d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSeptic shock\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMODS, Poor wound healing\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSadaghianloo et al. [\u003cspan style=\"color:blue;\"\u003e29\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e15\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G B\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCO, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eFrydenburg et al. [\u003cspan style=\"color:blue;\"\u003e30\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e78\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLLI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eG A, T\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eO\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCO, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRespiratory and renal failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRespiratory and renal failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eFrydenburg et al. [\u003cspan style=\"color:blue;\"\u003e30\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e71\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLLI\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G D\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eO\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eCO, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRespiratory and renal failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eRespiratory and renal failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMichaels et al. [\u003cspan style=\"color:blue;\"\u003e31\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e60\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLLI, OM, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G D\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e4d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNucifora et al. [\u003cspan style=\"color:blue;\"\u003e33\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e36\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eOM, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eTracy et al. [\u003cspan style=\"color:blue;\"\u003e42\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e13\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eOM, S\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eO\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026lt;1d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMacbeth et al. [\u003cspan style=\"color:blue;\"\u003e69\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e60\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI, ND\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G D, T, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, 30d-1y\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1.5mo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSeptic shock\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSeptic shock, renal failure\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 49.65pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eWarrian et al. [\u003cspan style=\"color:blue;\"\u003e76\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e36\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eF\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eSB\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eLLI, OM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZ III, G E, AD\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eO\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003ePOS, \u0026lt;3d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e19d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMODS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eMODS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 78pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eOn missed diagnosis\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1 (5.3)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 49.65pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eKatsoulis et al. [\u003cspan style=\"color:blue;\"\u003e37\u003c/span\u003e]\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 28.35pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e41\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.4pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eM\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eDS\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eP, LLI, ND\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eN/A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eA, LP\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e9d\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eHemorrhage\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56.7pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eNo\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003ch1 style='margin-top:.25in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:200%;font-size:24px;font-family:\"Times New Roman\",serif;color:#1F4E79;'\u003e\u003cspan style='font-size:13px;line-height:200%;font-family:\"Times\",serif;'\u003eBAAI: blunt abdominal aortic injury; M: male; F: female; DS: direct strike; SB: seat belt; CA: cardiopulmonary arrest; S: shock; P: pain; LLI: lower limb ischemia; OM: other manifestations; ND: neurological dysfunction; Z: zone; G: grade; T: thrombosis; AD: aortic degeneration; N/A: not available; A: injuries to organs in abdomen; LP: injuries to lumbar spine; O: injuries to other parts of body; POS: primary open surgery; CO: conservative observation; MODS: multiple organ dysfunction syndrome\u003cbr\u003e\u0026nbsp;\u003c/span\u003e\u003c/h1\u003e\n\u003cp style='margin-top:0in;margin-right:-92.4pt;margin-bottom:0in;margin-left:-7.1pt;line-height:normal;font-size:16px;font-family:\"Times New Roman\",serif;text-indent:-.1pt;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:13px;font-family:\"Times\",serif;'\u003eTable 2. \u0026nbsp;Univariate and multivariate analysis of death after BAAI\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cdiv align=\"center\" style='margin-top:0in;margin-right:0in;margin-bottom:8.0pt;margin-left:0in;line-height:200%;font-size:16px;font-family:\"Times New Roman\",serif;'\u003e\n \u003ctable style=\"width: 5.8e+2pt;border-collapse: collapse;border:none;\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 113.4pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eVariable\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width:170.1pt;border-top:solid windowtext 1.0pt;border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eUnivariate analysis\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width:141.75pt;border-top:solid windowtext 1.0pt;border-left:none;border-bottom:solid windowtext 1.0pt;border-right:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eMultivariate analysis 1\u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003csup\u003e\u003cspan style=\"font-size:9px;font-family:SimSun;\"\u003e\u0026dagger;\u003c/span\u003e\u003c/sup\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 127.6pt;border-width: 1pt medium;border-style: solid none;border-color: windowtext currentcolor;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eMultivariate analysis 2\u003c/span\u003e\u003c/strong\u003e\u003cstrong\u003e\u003csup\u003e\u003cspan style=\"font-size:9px;font-family:SimSun;\"\u003e\u0026Dagger;\u003c/span\u003e\u003c/sup\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:49.65pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eNum of obs\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eRelative risk (95% CI)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;value\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eRelative risk (95% CI)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;value\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eRelative risk (95% CI)\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cem\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eP\u003c/span\u003e\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;value\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAge (y)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e124\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1.018 (1.001-1.035)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.040\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1.054 (1.019-1.090)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.002\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1.004 (0.988-1.020)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e0.598\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eFemale\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e124\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e2.182 (0.966-4.929)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.061\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e0.494 (0.098-2.499)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e0.394\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e1.794 (0.788-4.083)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e0.164\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eInjury way\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e104\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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style='font-size:9px;font-family:\"Times\",serif;'\u003ePain\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.264 (0.108-0.648)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.004\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.263 (0.100-0.689)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.007\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.967 (0.255-3.659)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.960\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eLower limb ischemia\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.106 (0.883-5.023)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.093\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e8.170 (0.738-90.486)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.087\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e7.137 (1.154-44.161)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.035\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eNeurological dysfunction\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1.267 (0.416-3.857)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.677\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eOther manifestations\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1.397 (0.577-3.379)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.459\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eCardiopulmonary arrest\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e6.667 (3.580-12.415)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.70e+07 (1.62e+06~4.50e+08)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e10.250 (1.452-72.344)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.020\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eDelayed manifestations\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.439 (0.064-3.030)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.403\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eNo immediate manifestations\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e106\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eShock\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e99\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.207 (0.976-4.990)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.057\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.715 (0.603-12.224)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.193\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.552 (0.799-8.152)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.114\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAortic lesion location\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e9.28e-08 (1.86e-08~4.64e-07)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp; Zone II\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e3.281 (1.159-9.293)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.025\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-indent:7.0pt;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eZone III\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-indent:7.0pt;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eGrade A\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp; Grade B\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e4.143 (0.429-40.050)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.219\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e5.97e+05 (9.29e+04~3.84e+06)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp; Grade C\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.93e+05 (2.59e+04~3.33e+06)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp; Grade D\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e6.444 (1.284-32.334)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.024\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e8.45e+11 (1.09e+11~6.58e+12)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-indent:7.0pt;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003eGrade E\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e11.393 (2.706-47.968)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.06e+12 (2.99e+11~1.42e+13)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eThrombosis at aortic lesion\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e110\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1.750 (0.659-4.648)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.261\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAortic degeneration\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.972 (0.287-3.292)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.964\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eInjuries to organs in abdomen\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e124\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.569 (0.251-1.292)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.178\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.909 (0.399-2.071)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.821\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.624 (0.273-1.426)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.263\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eInjuries to lumbar spine\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e124\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.914 (0.330-2.534)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.863\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eInjuries to other parts of body\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e124\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.700 (1.209-6.031)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.017\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e4.775 (0.387-58.855)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.222\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e2.593 (1.189-5.655)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.017\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eCore treatment\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e102\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e0.083\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp; Secondary operation\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e3.12e+04 (7.06e+03~1.38e+05)\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cstrong\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026lt;0.001\u003c/span\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New 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style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eReference\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eTiming to core treatment after injury\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e91\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan 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Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eAdverse events\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e23\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eResidual lower limb ischemia\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e95\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border: medium;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width:113.4pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003eResidual neurological dysfunction\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:49.65pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e10\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:85.05pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e1\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.4pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\n \u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e-\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.2pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:106.3pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width:35.45pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 14.15pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:center;border:none;'\u003e\u003cspan style='font-size:9px;font-family: \"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92.15pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 35.45pt;border-width: medium medium 1pt;border-style: none none solid;border-color: currentcolor currentcolor windowtext;border-image: none;padding: 0in 5.4pt;vertical-align: top;\"\u003e\u0026nbsp;\u003cp style='margin-top:0in;margin-right:0in;margin-bottom:0in;margin-left:0in;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;border:none;'\u003e\u003cspan style='font-size:9px;font-family:\"Times\",serif;'\u003e\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cp style='margin-top:0in;margin-right:-60.95pt;margin-bottom:0in;margin-left:-14.15pt;line-height:12.0pt;font-size:16px;font-family:\"Times New Roman\",serif;text-align:justify;border:none;'\u003e\u003cspan style='font-size:13px;font-family:\"Times\",serif;'\u003eBAAI: blunt abdominal aortic injury; Num of obs: number of observations; CI: confidence interval\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003csup\u003e\u003cspan style='font-size:13px;line-height:200%;font-family:\"Times\",serif;'\u003e\u0026dagger;\u003c/span\u003e\u003c/sup\u003e\u003cspan style='font-size:13px;line-height:200%;font-family:\"Times\",serif;'\u003eAll variables with a \u003cem\u003eP\u003c/em\u003e value \u0026lt;0.20 from univariate analysis were included in the model; \u003csup\u003e\u0026Dagger;\u003c/sup\u003eVariables with a \u003cem\u003eP\u003c/em\u003e value \u0026lt;0.20 from univariate analysis and a relative risk value \u0026lt;1000 from multivariate analysis 1 were included in the model\u003c/span\u003e\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"BAAI, blunt trauma, abdominal injury, mortality, trauma","lastPublishedDoi":"10.21203/rs.3.rs-2703023/v2","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-2703023/v2","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eAt present, there are few studies on blunt abdominal aortic injury (BAAI), and most of them are case reports. Little is known about this disease. So, a systematic review was conducted through extensive search of major databases. All literature that provided individual (non-identifiable) data for BAAI patients could be included without being limited by study design. Additionally, regression analyses of predictors for death after BAAI were conducted. The search resulted in 2,099 hits, and 102 case reports and 1 conference abstract included in the review then. After assessment using the Joanna Briggs Institute checklist, no low-quality studies were found. A total of 133 patients were included, with a median age of 34 and 73.7% being males. Their most common clinical manifestation was pain (65.6%). The most common severity of aortic lesion was grade A (intimal tear or intramural hematoma, 46.9%), and the most common location of aortic lesion was zone III (infrarenal aorta, 88.3%). The overall mortality after BAAI was 15.3%. The following are the predictors for death after BAAI identified through multivariate regression analyses: lower limb ischemia [relative risk (RR), 7.137; 95% confidence interval (CI), 1.154-44.161], cardiopulmonary arrest (RR, 10.250; 95% CI, 1.452-72.344), and injuries to other parts (other than abdomen and lumbar spine) of body (RR, 2.593; 95% CI, 1.189-5.655). In conclusion, this study provides a detailed quantitative summary of the characteristics of the clinical manifestations, diagnosis, treatment, and prognosis of BAAI, a deadly traumatic disease, and indicates that the three variables above are risk factors for death.\u003c/p\u003e","manuscriptTitle":"A systematic review of blunt abdominal aortic injury and analysis of predictors for death","msid":"","msnumber":"","nonDraftVersions":[{"code":2,"date":"2023-10-11 21:47:33","doi":"10.21203/rs.3.rs-2703023/v2","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}},{"code":1,"date":"2023-03-23 18:59:46","doi":"10.21203/rs.3.rs-2703023/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"cf286ee5-8822-4676-8a97-c8ba72129061","owner":[],"postedDate":"October 11th, 2023","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[],"tags":[],"updatedAt":"2024-04-20T17:08:29+00:00","versionOfRecord":{"articleIdentity":"rs-2703023","link":"https://doi.org/10.17305/bb.2023.9831","journal":{"identity":"biomolecules-and-biomedicine","isVorOnly":true,"title":"Biomolecules and Biomedicine"},"publishedOn":"2023-10-21 17:08:29","publishedOnDateReadable":"October 21st, 2023"},"versionCreatedAt":"2023-10-11 21:47:33","video":"","vorDoi":"10.17305/bb.2023.9831","vorDoiUrl":"https://doi.org/10.17305/bb.2023.9831","workflowStages":[]},"version":"v2","identity":"rs-2703023","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-2703023","identity":"rs-2703023","version":["v2"]},"buildId":"cBFmMYwuxLRRLfASyISRj","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}