Simultaneous Bilateral Tubal Ectopic Pregnancy after Intracytoplasmic Sperm Injection and Embryo Transfer, in a Patient with Stage 3 Endometriosis

Tariq Baghdadi, A. Bordes, B Salle, G. Lamblin
In: Gynecology & Obstetrics Case report · 2016 · vol. 02(03) · doi:10.21767/2471-8165.1000035 · W2577802093
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This case report details a simultaneous bilateral tubal ectopic pregnancy in a 32-year-old patient with stage 3 endometriosis following intracytoplasmic sperm injection and embryo transfer.

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This case report describes a 32-year-old woman with primary infertility and stage 3 endometriosis who developed simultaneous bilateral tubal ectopic pregnancies following intracytoplasmic sperm injection and embryo transfer. The patient underwent laparoscopic salpingectomy to manage the condition, highlighting the increased risk of extra-uterine pregnancy associated with assisted reproductive technologies. The authors emphasize that serum hCG monitoring and transvaginal ultrasound are critical for screening until implantation sites are confirmed, even when hormone levels rise normally. This paper is centrally about endometriosis — specifically documenting its presence in a patient experiencing a rare complication of fertility treatment.

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Abstract

Objective: To describe a simultaneous bilateral tubal ectopic pregnancy after intracytoplasmic sperm injection and embryo transfer: A case report. Setting: Department of Reproductive Medicine, Femme- Mère-Enfant University Hospital, Bron, France. Introduction: The incidence of extra-uterine pregnancy increases to 2% to 12% following IVF-ET; several pathogenic theories have been suggested, including abnormal hormonal secretion or exogenous hormones administered in assisted reproductive technology (ART). Patient and method: A 32year-old nulliparous woman, with primary infertility and endometriosis stage 3, was treated by ART with intracytoplasmic sperm injection and embryo transfer. Result: The patient showed simultaneous bilateral extrauterine pregnancy, managed by laparoscopic salpingectomy. Discussion: The various possible pathophysiological mechanisms are described, with a review of the literature on simultaneous bilateral extra-uterine pregnancy following ART. Conclusion: In pregnancies following ART, ectopic pregnancy should always be screened for by serum hCG monitoring and transvaginal ultrasound until the implantation site can be confirmed, as incidence is higher than in spontaneous pregnancy. Even if serum hCG concentration increases normally, possible bilateral EP should always be investigated if no intrauterine gestational sac can be seen.
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Objective

To describe a simultaneous bilateral tubal ectopic pregnancy after intracytoplasmic sperm injection and embryo transfer: A case report. Setting: Department of Reproductive Medicine, Femme- Mère-Enfant University Hospital, Bron, France.

Introduction

The incidence of extra-uterine pregnancy increases to 2% to 12% following IVF-ET; several pathogenic theories have been suggested, including abnormal hormonal secretion or exogenous hormones administered in assisted reproductive technology (ART). Patient and method: A 32year-old nulliparous woman, with primary infertility and endometriosis stage 3, was treated by ART with intracytoplasmic sperm injection and embryo transfer.

Result

The patient showed simultaneous bilateral extrauterine pregnancy, managed by laparoscopic salpingectomy.

Discussion

The various possible pathophysiological mechanisms are described, with a review of the literature on simultaneous bilateral extra-uterine pregnancy following ART.

Conclusion

In pregnancies following ART, ectopic pregnancy should always be screened for by serum hCG monitoring and transvaginal ultrasound until the implantation site can be confirmed, as incidence is higher than in spontaneous pregnancy. Even if serum hCG concentration increases normally, possible bilateral EP should always be investigated if no intrauterine gestational sac can be seen. Select your language of interest to view the total content in your interested language - Aquaculture & Veterinary Science - Chemistry & Chemical Sciences - Clinical Sciences - Engineering - General Science - Genetics & Molecular Biology - Health Care & Nursing - Immunology & Microbiology - Materials Science - Mathematics & Physics - Medical Sciences - Neurology & Psychiatry - Oncology & Cancer Science - Pharmaceutical Sciences

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endometriosisinfertility

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