Hysterectomy facilitates preceptive behavior in rats

Harry Ahdieh, George N. Wade
In: Hormones and Behavior · 1983 · vol. 17(1) , pp. 134–137 · doi:10.1016/0018-506x(83)90022-3 · PMID:6862389 · W2010057498
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This study investigated how hysterectomy impacts preceptive behavior in rats, observing specific changes following the surgical procedure.

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Abstract

The effects of hysterectomy on proceptive behavior were investigated using several doses of estradiol benzoate (EB) and progesterone (P) in female rats. One week after surgery, ovariectomized (OV) and ovariectomized-hysterectomized (OH) rats were given three daily injections of 1.0 or 2.0 micrograms EB followed by 0.5 mg P or oil on the fourth day and were tested for solicitation 4 hr later. The same animals received 1.0 or 2.0 micrograms EB plus 0.1 mg P, or 4.0 micrograms EB plus oil on the same schedule a week following the first test and were tested again. Ovariectomized-hysterectomized animals receiving 0.5 mg P, regardless of the EB dose, showed significantly higher solicitation scores than OV animals, but the scores of the EB-primed OV and OH rats receiving 0.1 mg P or oil vehicle did not differ.

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