Endometriosis and both inflammatory and autoimmune dermatological diseases: a systematic review on the exploration of immunological mechanisms and clinical associations

This systematic review aims to investigate the association between endometriosis and the development of inflammatory and autoimmune dermatological diseases. The main objective is to determine whether women diagnosed with endometriosis have a higher risk of developing these skin conditions compared with women without endometriosis. The research will analyze observational studies published from 2016 onward, focusing on diseases such as psoriasis, hidradenitis suppurativa, atopic dermatitis, alopecia areata, vitiligo, chronic urticaria, cutaneous lupus erythematosus and acne vulgaris. Additionally, the review will explore potential shared inflammatory and immunological mechanisms that may explain these associations. The expected outcomes are to identify which dermatological diseases show the strongest associations with endometriosis, evaluate the consistency of the available evidence and contribute to a better understanding of their potential relationship.