Impacts of Community Health Reform on Rational Use of Drug in China: A Controlled Interrupted Time Series

Abstract Objective:To evaluate impacts of Baoan district Community Health Reform program in Shenzhen, Guangdong Province on reducing inappropriate use of antibiotics. This reform was designed to change physicians’ prescription behaviors. Methods: Statistical significance and effect size were calculated by segmented regression analysis of interrupted time series with a comparison group. Data of antibiotic use before and after the intervention on 1st June 2009 was collected between 1st October 2008 and 31th May 2010. Results: Community Health Reform program resulted in decreasing antibiotic use by 0.84%(P=0.0038) per month. Conclusion: Baoan district Community Health Reform constrains the abuse of antibiotics effectively. Appropriate drug use was prompted by this reform.