The Potential of Synthetic Twin Agents for Personalized Behavioural Interventions at Scale

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Abstract

Personalization is increasingly emphasized in behavioural public policy, yet traditional approaches to tailoring interventions remain costly and difficult to scale. Synthetic twin agents—AI-generated counterparts of real individuals—offer a novel, scalable approach. This study evaluates whether synthetic twins generated by large language models (LLMs) can replicate human responses to personality-tailored advertisements. We recruited 373 human participants and created matched synthetic twins using four LLMs (GPT-4o, GPT-5-latest, Gemini-1.5 Flash, and Gemini-2.0 Flash). Participants evaluated advertisements for three consumer products, each tailored to Big-Five personality traits. Both human participants and their synthetic twins demonstrated personality-congruent responses for Agreeableness and Extraversion. Synthetic twins additionally showed congruence for Conscientiousness and, in some cases, Neuroticism, depending on the model and product. Trait-level comparisons showed partial alignment: Gemini-1.5 Flash most closely replicated human patterns, followed by GPT-4o and Gemini-2.0 Flash; GPT-5-latest showed the weakest alignment. Despite trait-specific divergences, aggregate correlations between human and synthetic responses were high (r = .81-.91), indicating strong consistency in relative patterns. These findings provide early evidence that prompt-based multimodal LLMs can approximate human psychological responses. Synthetic twins may serve as low-cost tools for pre-testing personalized behavioural interventions, while also raising critical ethical concerns around privacy, governance, and hyper-personalization.

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europepmc
last seen: 2026-05-20T01:45:00.602351+00:00
unpaywall
last seen: 2026-05-22T02:00:06.705733+00:00
License: CC-BY-4.0