Outcomes of Same-Sex Female Couples Pursuing Autologous and Reciprocal In Vitro Fertilization

Diego D, Daniela Diego, Gaskins AJ, Audrey J. Gaskins, Heather S. Hipp, Jennifer F. Kawwass, Kawwass JF
JAMA · 2026 · vol. 335(10) , pp. 905–907 · doi:10.1001/jama.2025.26962 · PMID:41678200 · PMC12902921
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⚙ AI-generated summary by qwen3.7-flash, 2026-10-01 ⓘ

This study evaluates the reproductive outcomes of same-sex female couples utilizing autologous and reciprocal in vitro fertilization, providing data on clinical success rates for these specific assisted reproduction techniques.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-11-01 · read from full text ⓘ

This study evaluated embryo transfer and pregnancy outcomes among same-sex female couples in the United States undergoing reciprocal versus autologous oocyte in vitro fertilization cycles. The researchers analyzed data to compare the efficacy of using partner-derived eggs against self-derived eggs within the context of assisted reproductive technology for this demographic. The findings provide clinical insights into the success rates associated with different gamete sources for lesbian couples pursuing parenthood through IVF. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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An official website of the United States government The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. This study compares embryo transfer and pregnancy outcomes among US same-sex female couples undergoing reciprocal and autologous oocyte in vitro fertilization (IVF) cycles. Conflict of Interest Disclosures: Dr Gaskins reported serving as a scientific advisor to Doveras Fertility Inc and holding stock options in the company. No other disclosures were reported. References Aktoz F, Loreti S, Darici E, et al. IVF with reception of oocytes from partner in lesbian couples: a systematic review and SWOT analysis. Reprod Biomed Online. 2024;48(1):103411. doi: 10.1016/j.rbmo.2023.103411 - DOI - PubMed Choong E, Barry P, Bewley S, Meads C. Comparing the outcomes of in-vitro fertilization in same-sex female couples using their partner’s egg versus their own egg: a systematic review. J Homosex. Published online August 19, 2025. doi: 10.1080/00918369.2025.2537837 - DOI - PubMed Brandão P, Ceschin N. Lesbian shared IVF: the ROPA method: a systematic review. Porto Biomed J. 2023;8(2):e202. doi: 10.1097/j.pbj.0000000000000202 - DOI - PMC - PubMed Matorras R, Perez-Fernandez S, Hubel A, et al. Perinatal outcomes in lesbian couples employing shared motherhood IVF compared with those performing artificial insemination with donor sperm. Hum Reprod. 2023;38(5):895-907. doi: 10.1093/humrep/dead035 - DOI - PubMed Núñez A, García D, Giménez-Bonafé P, Vassena R, Rodríguez A. Reproductive outcomes in lesbian couples undergoing reception of oocytes from partner versus autologous in vitro fertilization/intracytoplasmic sperm injection. LGBT Health. 2021;8(5):367-371. doi: 10.1089/lgbt.2020.0282 - DOI - PubMed

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