Ventral Lengthening Is Preferable to Combined Ventral Lengthening and Dorsal Plication for Penile Length in Hypospadias with Severe Ventral Curvature

Ventral Lengthening Is Preferable to Combined Ventral Lengthening and Dorsal Plication for Penile Length in Hypospadias with Severe Ventral Curvature | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Ventral Lengthening Is Preferable to Combined Ventral Lengthening and Dorsal Plication for Penile Length in Hypospadias with Severe Ventral Curvature Lizhe Hu, Hongbo Liu, Xiang Yan, Guangjie Chen, Wei Ru This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6728205/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 16 Feb, 2026 Read the published version in Scientific Reports → Version 1 posted 14 You are reading this latest preprint version Abstract Purpose This study aims to compare the effects of ventral lengthening (VL) versus ventral lengthening combined with dorsal plication (VL + DP) techniques on penile length in hypospadias. Materials and Methods Clinical data were retrospectively collected from patients who underwent hypospadias repairs with urethral plate transection between March 2017 and June 2023. Patients were divided into VL group and VL + DP group based on the curvature correction techniques. Two novel parameters—penile lengthening ratio (PLR) and curvature-adjusted penile lengthening ratio (CPLR)—were introduced to evaluate the effectiveness of penile lengthening. Results A total of 103 male patients with hypospadias and severe ventral curvature were included. In patients with a curvature degree after degloving (CDAD) greater than 45°, the CPLR was significantly higher in the VL group compared to that in the VL + DP group (0.0101 ± 0.0028 vs 0.0085 ± 0.0024, p = 0.026). Among patients with proximal hypospadias, the CPLR in the VL group was significantly higher than that in the VL + DP group (0.0106 ± 0.0024 vs 0.0093 ± 0.0026, p = 0.041). Conclusions In patients with CDAD > 45° or proximal hypospadias, VL demonstrated superior penile elongation compared to VL + DP. Health sciences/Urology/Paediatric urology/Hypospadias Health sciences/Anatomy/Urinary tract/Urethra Hypospadias Curvature correction Urethral plate transection Ventral lengthening Dorsal plication Penile length Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 16 Feb, 2026 Read the published version in Scientific Reports → Version 1 posted Editorial decision: Revision requested 17 Oct, 2025 Reviewers agreed at journal 07 Aug, 2025 Reviewers agreed at journal 09 Jul, 2025 Reviewers agreed at journal 08 Jul, 2025 Reviews received at journal 11 Jun, 2025 Reviews received at journal 10 Jun, 2025 Reviewers agreed at journal 31 May, 2025 Reviewers agreed at journal 29 May, 2025 Reviewers agreed at journal 29 May, 2025 Reviewers invited by journal 29 May, 2025 Editor invited by journal 28 May, 2025 Editor assigned by journal 24 May, 2025 Submission checks completed at journal 23 May, 2025 First submitted to journal 22 May, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6728205","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":464623907,"identity":"f258affb-6674-4681-8cf6-f7c35ddc6085","order_by":0,"name":"Lizhe Hu","email":"","orcid":"","institution":"Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou","correspondingAuthor":false,"prefix":"","firstName":"Lizhe","middleName":"","lastName":"Hu","suffix":""},{"id":464623908,"identity":"c5bcb0e0-00af-46d9-a2d4-50198d07a94c","order_by":1,"name":"Hongbo Liu","email":"","orcid":"","institution":"Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou","correspondingAuthor":false,"prefix":"","firstName":"Hongbo","middleName":"","lastName":"Liu","suffix":""},{"id":464623909,"identity":"d3676064-9281-4a68-9205-0d883247ce83","order_by":2,"name":"Xiang Yan","email":"","orcid":"","institution":"Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou","correspondingAuthor":false,"prefix":"","firstName":"Xiang","middleName":"","lastName":"Yan","suffix":""},{"id":464623910,"identity":"9adcbb23-5948-4e38-812d-a077b07327b8","order_by":3,"name":"Guangjie Chen","email":"","orcid":"","institution":"Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou","correspondingAuthor":false,"prefix":"","firstName":"Guangjie","middleName":"","lastName":"Chen","suffix":""},{"id":464623911,"identity":"13d48761-0b35-47e8-bf8f-cbd440021d98","order_by":4,"name":"Wei Ru","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAAs0lEQVRIiWNgGAWjYLCChAoGZhAtQYKWMyRrYWyD0MRpMZ+RY/jg4bw6doMDzAdv8zDY5RHUInMjx9ggcRsbs8EBtmRrHobkYoJaJCRyt0kkbuMBauExk+ZhOJDYQISW7T8S50gAtfB/I1rLNobEBgOQLWxEauF5/1ki4VgCs+RhNmPLOQbJRGhhT0v8+KOmLpnvePPDG28q7AhrgYFkSGQaEKseCOxIUDsKRsEoGAUjDQAAwckzQAkCQykAAAAASUVORK5CYII=","orcid":"","institution":"Department of Urology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou","correspondingAuthor":true,"prefix":"","firstName":"Wei","middleName":"","lastName":"Ru","suffix":""}],"badges":[],"createdAt":"2025-05-23 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Curvature","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Hypospadias, Curvature correction, Urethral plate transection, Ventral lengthening, Dorsal plication, Penile length","lastPublishedDoi":"10.21203/rs.3.rs-6728205/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6728205/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003ePurpose\u003c/h2\u003e \u003cp\u003eThis study aims to compare the effects of ventral lengthening (VL) versus ventral lengthening combined with dorsal plication (VL\u0026thinsp;+\u0026thinsp;DP) techniques on penile length in hypospadias.\u003c/p\u003e\u003ch2\u003eMaterials and Methods\u003c/h2\u003e \u003cp\u003eClinical data were retrospectively collected from patients who underwent hypospadias repairs with urethral plate transection between March 2017 and June 2023. Patients were divided into VL group and VL\u0026thinsp;+\u0026thinsp;DP group based on the curvature correction techniques. Two novel parameters\u0026mdash;penile lengthening ratio (PLR) and curvature-adjusted penile lengthening ratio (CPLR)\u0026mdash;were introduced to evaluate the effectiveness of penile lengthening.\u003c/p\u003e\u003ch2\u003eResults\u003c/h2\u003e \u003cp\u003eA total of 103 male patients with hypospadias and severe ventral curvature were included. In patients with a curvature degree after degloving (CDAD) greater than 45\u0026deg;, the CPLR was significantly higher in the VL group compared to that in the VL\u0026thinsp;+\u0026thinsp;DP group (0.0101\u0026thinsp;\u0026plusmn;\u0026thinsp;0.0028 vs 0.0085\u0026thinsp;\u0026plusmn;\u0026thinsp;0.0024, \u003cem\u003ep\u003c/em\u003e\u0026thinsp;=\u0026thinsp;0.026). Among patients with proximal hypospadias, the CPLR in the VL group was significantly higher than that in the VL\u0026thinsp;+\u0026thinsp;DP group (0.0106\u0026thinsp;\u0026plusmn;\u0026thinsp;0.0024 vs 0.0093\u0026thinsp;\u0026plusmn;\u0026thinsp;0.0026, \u003cem\u003ep\u003c/em\u003e\u0026thinsp;=\u0026thinsp;0.041).\u003c/p\u003e\u003ch2\u003eConclusions\u003c/h2\u003e \u003cp\u003eIn patients with CDAD\u0026thinsp;\u0026gt;\u0026thinsp;45\u0026deg; or proximal hypospadias, VL demonstrated superior penile elongation compared to VL\u0026thinsp;+\u0026thinsp;DP.\u003c/p\u003e","manuscriptTitle":"Ventral Lengthening Is Preferable to Combined Ventral Lengthening and Dorsal Plication for Penile Length in Hypospadias with Severe Ventral Curvature","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-06-02 19:21:20","doi":"10.21203/rs.3.rs-6728205/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-10-17T19:53:51+00:00","index":"","fulltext":""},{"type":"reviewerAgreed","content":"107844403940376993764534103588857728740","date":"2025-08-07T13:12:47+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"75681398035606733470774192507046448239","date":"2025-07-09T16:38:17+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"156095014062665875349928907991427180171","date":"2025-07-08T18:14:45+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-06-11T07:39:42+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-06-10T11:39:33+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"121630137721012481144619562962150207173","date":"2025-05-31T17:45:44+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"210373316762182062406254778586499853591","date":"2025-05-29T13:32:58+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"317689557404802785892905599962896762975","date":"2025-05-29T12:49:05+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-05-29T12:46:10+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2025-05-28T11:48:32+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-05-24T10:30:39+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-05-23T12:36:16+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2025-05-23T00:34:06+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"89bdbf2a-38f2-43e4-9018-7d8119a6653b","owner":[],"postedDate":"June 2nd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":49332679,"name":"Health sciences/Urology/Paediatric urology/Hypospadias"},{"id":49332680,"name":"Health sciences/Anatomy/Urinary tract/Urethra"}],"tags":[],"updatedAt":"2026-02-23T16:12:50+00:00","versionOfRecord":{"articleIdentity":"rs-6728205","link":"https://doi.org/10.1038/s41598-026-38874-0","journal":{"identity":"scientific-reports","isVorOnly":false,"title":"Scientific Reports"},"publishedOn":"2026-02-16 15:58:56","publishedOnDateReadable":"February 16th, 2026"},"versionCreatedAt":"2025-06-02 19:21:20","video":"","vorDoi":"10.1038/s41598-026-38874-0","vorDoiUrl":"https://doi.org/10.1038/s41598-026-38874-0","workflowStages":[]},"version":"v1","identity":"rs-6728205","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6728205","identity":"rs-6728205","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}