Umbilical nodule, a rare presentation of primary cutaneous endometriosis: Case report and literature review

John Adi Ashindoitiang, Victor Ikechukwu Canice Nwagbara, Victor Nwagbara, Theophilus Ipeh Ugbem, Joseph Stephen Ukam, Maurice Efana Asuquo
Rare tumors · 2024 · vol. 16 , pp. 20363613241285148 · doi:10.1177/20363613241285148 · PMID:39290294 · PMC11406645 · W4402546319
case-report OA: gold CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

Primary umbilical endometriosis, presenting as cyclical pain and bleeding within the umbilicus, was confirmed histologically in a 30-year-old woman and should be considered in reproductive-aged females with related symptoms.

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Abstract

Umbilical endometriosis or Villar's nodule is defined as the presence of endometrial tissue within the umbilicus and represent 0.5%-1% cases of endometriosis ectopia. It is classified as primary or secondary based on the surgical history. The important symptoms that characterize primary umbilical endometriosis were cyclical pain and a palpable mass that may be associated with bleeding. These features have temporal association with catamenia. Presented is a 30 year old woman with clinical features that suggested primary umbilical endometriosis in the past 5 years. It was confirmed by histology and coexisted with uterine fibroid. In the absence of previous surgery, primary umbilical endometriosis should be considered in the differential diagnosis in females of reproductive age with umbilical pain and nodule related to catamenia. Surgery is the treatment of choice and this should be individualized as some lesions can be managed by local excision with satisfactory outcome regarding the cessation of the presenting symptoms with good cosmetic outcome.

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Condition tags

endometriosis

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