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Are We Falling Short? Evaluating the Accuracy of Common Clinical Fall Risk Assessments in Stroke Survivors: A Systematic Review and Meta-Analysis | medRxiv /* */ /* */ <!-- <!-- /*! * yepnope1.5.4 * (c) WTFPL, GPLv2 */ (function(a,b,c){function d(a){return"[object Function]"==o.call(a)}function e(a){return"string"==typeof a}function f(){}function g(a){return!a||"loaded"==a||"complete"==a||"uninitialized"==a}function h(){var a=p.shift();q=1,a?a.t?m(function(){("c"==a.t?B.injectCss:B.injectJs)(a.s,0,a.a,a.x,a.e,1)},0):(a(),h()):q=0}function i(a,c,d,e,f,i,j){function k(b){if(!o&&g(l.readyState)&&(u.r=o=1,!q&&h(),l.onload=l.onreadystatechange=null,b)){"img"!=a&&m(function(){t.removeChild(l)},50);for(var d in y[c])y[c].hasOwnProperty(d)&&y[c][d].onload()}}var j=j||B.errorTimeout,l=b.createElement(a),o=0,r=0,u={t:d,s:c,e:f,a:i,x:j};1===y[c]&&(r=1,y[c]=[]),"object"==a?l.data=c:(l.src=c,l.type=a),l.width=l.height="0",l.onerror=l.onload=l.onreadystatechange=function(){k.call(this,r)},p.splice(e,0,u),"img"!=a&&(r||2===y[c]?(t.insertBefore(l,s?null:n),m(k,j)):y[c].push(l))}function j(a,b,c,d,f){return q=0,b=b||"j",e(a)?i("c"==b?v:u,a,b,this.i++,c,d,f):(p.splice(this.i++,0,a),1==p.length&&h()),this}function k(){var a=B;return a.loader={load:j,i:0},a}var l=b.documentElement,m=a.setTimeout,n=b.getElementsByTagName("script")[0],o={}.toString,p=[],q=0,r="MozAppearance"in l.style,s=r&&!!b.createRange().compareNode,t=s?l:n.parentNode,l=a.opera&&"[object Opera]"==o.call(a.opera),l=!!b.attachEvent&&!l,u=r?"object":l?"script":"img",v=l?"script":u,w=Array.isArray||function(a){return"[object Array]"==o.call(a)},x=[],y={},z={timeout:function(a,b){return b.length&&(a.timeout=b[0]),a}},A,B;B=function(a){function b(a){var a=a.split("!"),b=x.length,c=a.pop(),d=a.length,c={url:c,origUrl:c,prefixes:a},e,f,g;for(f=0;f<d;f++)g=a[f].split("="),(e=z[g.shift()])&&(c=e(c,g));for(f=0;f<b;f++)c=x[f](c);return c}function g(a,e,f,g,h){var i=b(a),j=i.autoCallback;i.url.split(".").pop().split("?").shift(),i.bypass||(e&&(e=d(e)?e:e[a]||e[g]||e[a.split("/").pop().split("?")[0]]),i.instead?i.instead(a,e,f,g,h):(y[i.url]?i.noexec=!0:y[i.url]=1,f.load(i.url,i.forceCSS||!i.forceJS&&"css"==i.url.split(".").pop().split("?").shift()?"c":c,i.noexec,i.attrs,i.timeout),(d(e)||d(j))&&f.load(function(){k(),e&&e(i.origUrl,h,g),j&&j(i.origUrl,h,g),y[i.url]=2})))}function h(a,b){function c(a,c){if(a){if(e(a))c||(j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}),g(a,j,b,0,h);else if(Object(a)===a)for(n in m=function(){var b=0,c;for(c in a)a.hasOwnProperty(c)&&b++;return b}(),a)a.hasOwnProperty(n)&&(!c&&!--m&&(d(j)?j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}:j[n]=function(a){return function(){var b=[].slice.call(arguments);a&&a.apply(this,b),l()}}(k[n])),g(a[n],j,b,n,h))}else!c&&l()}var h=!!a.test,i=a.load||a.both,j=a.callback||f,k=j,l=a.complete||f,m,n;c(h?a.yep:a.nope,!!i),i&&c(i)}var i,j,l=this.yepnope.loader;if(e(a))g(a,0,l,0);else if(w(a))for(i=0;i (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0];var j=d.createElement(s);var dl=l!='dataLayer'?'&l='+l:'';j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;j.type='text/javascript';j.async=true;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-P4HH5NV'); Skip to main content Home About Submit ALERTS / RSS Search for this keyword Advanced Search Are We Falling Short? Evaluating the Accuracy of Common Clinical Fall Risk Assessments in Stroke Survivors: A Systematic Review and Meta-Analysis View ORCID Profile Marina Meyer-Vega , Nojan Valadi , View ORCID Profile Daniel J. Goble , Niyati Baweja , View ORCID Profile Harsimran S. Baweja doi: https://doi.org/10.1101/2025.06.15.25329158 Marina Meyer-Vega 1 School of Kinesiology, Auburn University , Auburn, AL, USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Marina Meyer-Vega Nojan Valadi 2 Neurology Center of East Alabama , Auburn, AL, USA MD Find this author on Google Scholar Find this author on PubMed Search for this author on this site Daniel J. Goble 3 School of Health Sciences, Oakland University , Rochester, MI, USA PHD Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Daniel J. Goble Niyati Baweja 1 School of Kinesiology, Auburn University , Auburn, AL, USA PT Find this author on Google Scholar Find this author on PubMed Search for this author on this site Harsimran S. Baweja 1 School of Kinesiology, Auburn University , Auburn, AL, USA PT PHD Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Harsimran S. Baweja For correspondence: hsb0025{at}auburn.edu Abstract Full Text Info/History Metrics Data/Code Preview PDF ABSTRACT Stroke survivors experience a significant risk of falls, with 73% falling within the first year post stroke. Clinical practice guidelines currently use more than 27 assessment tools to evaluate fall risk in this population. However, there are conflicting findings regarding their diagnostic accuracy in correctly identifying those at risk of falling. This systematic review and meta-analysis evaluates the sensitivity and specificity of the Timed Up and Go and the Berg Balance Scale, which are the most commonly used clinical assessments for identifying fall risk among stroke survivors. Our data search included Web of Science, PubMed, and Ovid Medline. This protocol was registered in PROSPERO (CRD420251004460) prior to data extraction. Fifteen studies, comprising 1,492 stroke survivors, were included in the meta-analysis. We found a negative association between these tests and their ability to accurately identify fall risk in this population (OR = 0.469, 95% CI [-0.230, 1.169], however, this was not statistically significant ( p = 0.188). No heterogeneity was observed across studies (τ 2 = 0.000; I² = 0%). We found considerable variability in cut-off values across protocols, without significant moderating effects of these thresholds on their diagnostic accuracy. No publication bias was detected according to the Egger’s weighted test (t (20) = 0.024, p = 0.981) and the rank correlation test (τ = - 0.030, p = 0.867). Future research should focus on developing or implementing an objective stroke-specific fall risk assessment with appropriate cut-off values that better capture the underlying mechanisms of fall risk in stroke survivors to improve fall prevention strategies and rehabilitation care. INTRODUCTION Stroke is a major global health concern, affecting approximately 15 million people worldwide each year [ 1 ]. In the United States alone, every 40 seconds, someone suffers from a stroke, making it one of the leading causes of death and long-term disability in the country [ 2 ]. The neurological damage from stroke often results in multiple stroke-related impairments that significantly contribute to reduced balance and fall risk, including neuromuscular weakness, lack of multisensory integration, reduced attention, and deficits in vision and spatial awareness [ 3 – 7 ]. Consequently, 7% of stroke survivors experience a fall in the first week and 73% in the first year post-stroke [ 3 , 8 ]. In light of the above, stroke survivors are six times more likely to experience a fall when compared with healthy individuals [ 9 , 10 ]. Falls can lead to serious consequences, including fractures, reduced quality of life, prolonged length of hospital stays, and a heavy financial burden [ 11 , 12 ]. Moreover, individuals with a history of falls are more susceptible to future falls and increased mortality [ 13 , 14 ]. This makes fall prevention a significant economic and healthcare priority in this population, highlighting the importance of clinical assessment tools and tests to specifically evaluate fall risk in stroke survivors, which are critical for high-quality, effective rehabilitation and preventing future falls [ 15 , 16 ]. Clinical assessment tools have the purpose of providing objective and reproducible data that can inform diagnosis and treatment planning, predict outcomes and/or prognosis, and monitor individual progress over time [ 16 – 19 ]. Despite these clear objectives, clinicians currently use more than 27 different tests, tools, and instruments to assess fall risk in stroke survivors [ 16 ]. This overabundance and inconsistency present a challenge to correctly inform clinical practice guidelines (CPGs). It complicates decision-making when selecting appropriate assessment tools. Moreover, standardized assessments are an essential element of evidence-based rehabilitation [ 20 ]. However, in this case, the lack of standardization across tests complicates the comparison of outcomes and identifying the most effective intervention [ 21 ]. In 2019, Dos Santos et al. reviewed the most common tools used in current CPGs for stroke survivors worldwide [ 16 ]. Among the 19 CPGs included in the review, the most frequently used were the Timed Up and Go (80%), the Berg Balance Scale (90%), the 6-Minute Walk Test (80%), and the 10-Meter Walk Test (70%) [ 16 ]. However, some groups have raised concerns regarding the diagnostic accuracy of these tests, specifically their sensitivity and specificity in differentiating between fallers and non-fallers, suggesting that clinicians should exercise caution in their application [ 22 , 23 ]. Sensitivity refers to a test’s ability to correctly identify those at risk of falling (true positives), while specificity refers to a test’s ability to correctly identify those not at risk of falling (true negatives) [ 24 , 25 ]. Findings suggest that common stroke assessment tools may overestimate or miscategorize fall risk [ 23 , 26 ]. Categorizing patients as high fall risk when they are not leads to unwarranted additional assessments and interventions [ 27 ]. Perhaps more concerning, misclassification can create an elevated fear of falling, potentially decreasing their independence and discouraging them from engaging in activities they are fully capable of performing [ 28 ]. In contrast, other groups have shown that common stroke assessment tools have excellent interrater reliability [ 29 – 31 ]. They are easy to administer and serve as an effective clinical tool for assessing functional mobility and balance [ 32 , 33 ]. Given the conflicting findings on the sensitivity and specificity of the most commonly used fall risk assessment tools and their critical role in fall prevention strategies for stroke survivors, a more comprehensive evaluation of their diagnostic efficacy is necessary. This systematic review and meta-analysis aim to evaluate the sensitivity and specificity of the most commonly used clinical assessments for identifying fall risk among stroke survivors. The findings of this study will: 1) inform current CPGs whether existing tests demonstrate sufficient diagnostic accuracy to predict fall risk and guide rehabilitation interventions and outcomes accurately; 2) determine which of these assessment tools demonstrate the highest sensitivity and specificity, potentially establishing it as a standard across CPGs; and 3) if no current assessment tools demonstrate adequate diagnostic accuracy for predicting fall risk in this population, highlight the need to develop and implement an objective, sensitive, stroke-specific fall risk assessment tool to improve diagnostic accuracy and its impact on the rehabilitation outcomes in stroke survivors. METHODS A systematic search was conducted according to the updated Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines [ 34 ]. The protocol was registered in the International Prospective Register of Systematic Reviews ( https://www.crd.york.ac.uk/PROSPERO/ ; Unique identifier: CRD420251004460). Search Strategy and Data Extraction An electronic search was performed by the lead author (MMV) in several electronic databases: Web of Science, PubMed, SportDiscuss, and Ovid MEDLINE from inception up to 03 March 2025. The search terms were prepared by the lead author (MMV) using Boolean operators in the following format: ((Stroke OR Cerebrovascular OR CVA) AND (Accidental fall* OR fall* OR fall risk OR fall prevention OR fall assessment*) AND (postural sway OR postural control OR postural balance OR dynamic balance OR static balance) AND (risk assessment OR balance test OR balance assessment OR balance measure OR clinical measure* OR Timed Up and Go OR TUG OR Berg Balance OR BBS OR 6 Minute Walk Test OR 6MWT OR 10 Meter Walk Test or 10MWT) AND (sensitivity OR specificity OR measurement properties OR psychometric OR predictive value OR multivariate analysis)). Two reviewers independently screened the titles and abstracts of all remaining studies for eligibility. After removing studies irrelevant to the research question, full-text articles of potentially eligible studies underwent a second independent screening. Any disagreements between reviewers were resolved through discussion and consensus. This systematic review and meta-analysis included studies that met the following criteria. Inclusion and Exclusion Criteria Studies were included if they (a) were articles published in English or Spanish; (b) Participants with a medical diagnosis of stroke without any other neurological or musculoskeletal condition; (c) included the outcome of at least one of the following tests: (1) Timed Up and Go; (2) Berg Balance Scale; (3) 10-Meter Walk Test; (4) 6-Minute Walk Test; and (d) provided sufficient data to calculate effect size (e.g., number of true fallers, number of true non-fallers, sensitivity and specificity of the test). Studies classified as case reports, articles presented at conferences, systematic reviews, or meta-analysis studies were excluded from the analysis. Study Selection The lead author (MMV) systematically extracted relevant information from all included studies using Microsoft Excel (Microsoft Corporation, Redmond, WA, USA, version 16.88). The data extracted included authors, year of publication, study design, sample size (total fallers and non-fallers), diagnostic performance metrics (sensitivity and specificity, true positives (TP), true negatives (TN), false positives (FP), and false negatives (FN)), and participants’ demographics (e.g., affected side, sex, and age). For studies that did not directly report the contingency table values (TP, TN, FP, FN), we derived these values from the reported sensitivity, specificity, and the known number of true fallers and non-fallers. TP were calculated as the product of sensitivity and the total number of fallers. TN were calculated as the product of specificity and the total number of non-fallers. FP were derived by multiplying the complement of specificity (1-specificity) by the total number of non-fallers. Finally, FN were calculated by subtracting the TP from the total number of fallers [ 35 ]. Statistical Analysis The effect size for each study was calculated using the natural logarithm of odds ratio (logOR), along with its variance using the following formulas [ 36 , 37 ]: Where a represents the number of true positives, d represents the number of true negatives, b represents the number of false positives, and c represents the number of false negatives. To facilitate the interpretation of the results, logOR and its confidence intervals were back transformed into OR for all interpretations using the following formulas [ 38 ]: An OR of more than 1 indicates that the clinical tests effectively discriminate between fallers and non-fallers. The higher the OR the stronger the clinical test’s ability to correctly classify stroke survivors. This meta-analysis used a weighted random-effects model with the restricted maximum likelihood estimator (REML) [ 39 ]. The heterogeneity across included studies was quantified using the estimated tau-squared (τ 2 ) value, representing the variance of the true effect sizes [ 40 ]. The I 2 statistic was also calculated to determine the percentage of total variability attributable to heterogeneity [ 40 , 41 ]. A Q-test was conducted to assess the presence of heterogeneity, with its associated p-value indicating whether the observed heterogeneity was statistically significant [ 40 , 41 ]. Additionally, we performed a subgroup analysis to compare the diagnostic accuracy between the tests and a meta-regression analysis to examine whether the cut-off values used for each test significantly moderate their diagnostic accuracy. The model results were reported as the estimated effect size (OR), standard error (SE), z-value, and p-value. The 95% confidence interval (CI) for the effect size was calculated to provide a range of plausible values. All statistics were executed using the statistical software package JASP (JASP Team, University of Amsterdam, Netherlands, version 0.19.2). Sensitivity Analysis and Risk of Bias We evaluated publication bias using Egger’s weighted regression test. Moreover, funnel plot asymmetry was assessed through a rank correlation test. To determine the robustness of the results, we conducted a leave-one-out sensitivity analysis by systematically removing each study individually from repeated meta-analyses to evaluate its impact on the overall findings. RESULTS Search Results Our search strategy identified 899 studies, with 674 remaining after removing 225 duplicates. Following title and abstract screening, 138 studies were selected for full-text review. Of the remaining studies, only 15 were eligible for data extraction, as detailed in Fig. 1 . Of these 15 studies, six exclusively evaluated the Berg Balance Scale [ 42 – 47 ], three focused on the Timed Up and Go [ 48 – 50 ], and six examined both tests ( Table 1 ) [ 51 – 56 ]. Furthermore, our search identified only three eligible studies for the 6-Minute and 10-Meter Walk Test. This small sample size was insufficient to calculate their effect size. Consequently, we excluded all studies evaluating only these tests from our final analysis. Download figure Open in new tab Figure 1. PRISMA 2020 flowchart of study selection. View this table: View inline View popup Table 1. Characteristics of the Berg Balance Scale (BBS) and the Timed Up and Go (TUG) test from the 15 included studies. Study Characteristics This systematic review analyzed data from 1,492 stroke survivors across the 15 included studies ( Table 2 ). Among participants, 35.8% (534) experienced falls, and 64.2% (958) were non-fallers. The demographic and clinical characteristics presented are based solely on variables that were reported in the studies. Participants had a mean age of 58±6 yrs, with 59.41% (792) males and 40.59% (541) females. Regarding stroke lateralization, 51.02% (447) suffered a right hemisphere stroke, 48.05% (421) had a left hemisphere stroke, and 0.93% (8) presented bilateral or unspecified stroke side. View this table: View inline View popup Table 2. Demographic and clinical characteristics of stroke survivors from the 15 included studies. Meta-analysis A weighted random-effects model with the REML method was fitted to the 15 studies to estimate the overall effect of the Timed Up and Go test and the Berg Balance Scale on the odds of correctly identifying true non-fallers and fallers among stroke survivors. The pooled effect size indicated a negative association (OR = 0.469, 95% CI [-0.230, 1.169] ( Fig. 2 ). However, this result was not statistically significant ( p = 0.188). There was no evidence of heterogeneity among studies (Q = 0.797, df (20), p = 1.000). The estimated amount of total heterogeneity (τ 2 = 0.000) and the I 2 statistic (0%) indicated that none of the observed variability was due to heterogeneity between studies, suggesting consistency in the findings across the included studies. Download figure Open in new tab Figure 2. Forest plot of studies included in the meta-analysis examining the overall pooled effect of the Berg Balance Scale and Timed Up and Go test on the odds of correctly identifying true non-fallers and fallers among stroke survivors. The forest plot displays each study’s effect size (odds ratio) along with its 95% confidence interval (CI). The diamond at the bottom represents the pooled effect size association (OR = 0.469, 95% CI [-0.230, 1.169], which falls below 1, indicating a negative association between these tests and their ability to correctly identify fallers and non-fallers among stroke survivors. However, these results are not statistically significant ( p = 0.188). Subgroup analysis revealed that the type of tests did not significantly moderate the observed effects (Qₘ = 0.002, p = 0.963), indicating no significant difference in diagnostic accuracy between the Timed Up and Go test and the Berg Balance Scale. Further meta-regression analyses examining the cut-off values showed no significant moderation of diagnostic accuracy for either the Timed Up and Go test (Qₘ = 0.015, p = 0.902) or the Berg Balance Scale (Qₘ = 0.018, p = 0.894). Sensitivity Analysis and Risk of Bias Publication bias assessment using Egger’s weighted test (t (20) = 0.024, p = 0.981), and the rank correlation test (τ = -0.030, p = 0.867) indicated no significant funnel plot asymmetry ( Fig. 3 ), demonstrating the absence of publication bias in the analyzed studies. Sensitivity analysis, conducted through leave-one-out analysis, revealed that none of the studies had a significant influence on the pooled effect size. Download figure Open in new tab Figure 3. Funnel plot of the 15 studies included in the meta-analysis. Each point represents an individual study, the x-axis represents the standard error, and the y-axis is each study’s effect size (odds ratio). The symmetrical distribution of studies suggests an absence of publication bias, which is confirmed by the Egger’s weighted test (t (20) = 0.024, p = 0.981) and the rank correlation test (τ = -0.030, p = 0.867). DISCUSSION This systematic review and meta-analysis evaluated the diagnostic accuracy of the most commonly used clinical assessments— the Timed Up and Go test and Berg Balance Scale—for identifying fall risk among stroke survivors. Our key findings were: 1) Over one-third (35.8%) of stroke survivors experience a fall; 2) The Timed Up and Go and the Berg Balance Scale demonstrated a negative association in accurately identifying fall risk in this population, though this was not statistically significant; 3) cut-off values varied widely across studies; however, adjusting these thresholds does not significantly improve diagnostic accuracy for fall risk classification in stroke survivors. Demographic and Clinical Characteristics We analyzed data from 15 papers with a total of 1,492 stroke survivors with a mean age of 58 ± 6 years. The sex distribution (59.41% male, 40.59% female) aligns with other findings, where men generally have a higher stroke incidence at young ages (45-74 years) [ 57 ]. However, as age increases, the difference is inverted, with females experiencing a higher incidence and mortality rate above 74 years of age [ 57 , 58 ]. The relatively balanced distribution of stroke lateralization (51.02% right hemisphere, 48.05% left hemisphere) reduces an overrepresentation of either hemisphere stroke. This is particularly important as hemispheric specialization influences balance and mobility. For example, a right hemisphere stroke often affects spatial awareness, left-sided neglect, and visual-spatial areas [ 59 ]. In contrast, left hemisphere strokes may have a greater impact on movement planning, sequencing, and language [ 60 ]. The fall incidence of 35.8% observed across studies is consistent with previous findings reporting fall rates between 25-73% during the first year post stroke [ 61 – 64 ]. Meta-analysis Our meta-analysis found a negative association (OR = 0.469, 95% CI [-0.230, 1.169]) between the Timed Up and Go test and the Berg Balance Scale and their diagnostic accuracy in identifying fall risk in stroke survivors. However, this finding was not statistically significant ( p = 0.188). Nevertheless, our findings call into question their effectiveness as standard components of post-stroke clinical protocols. The clinical implications of these findings are substantial, given that clinicians currently rely on these tests to make decisions about discharge planning and stroke rehabilitation [ 65 , 66 ]. If the diagnostic accuracy of these tools is limited in stroke survivors, this could directly affect patient safety and rehabilitation outcomes through inappropriate fall risk classification, potentially leading to misclassification of fall risk, resulting in a high rate of false positives and false negatives. Several factors may explain the above negative association. First, these tests were not explicitly created for stroke survivors, but were initially developed for older adults and later applied to the stroke population [ 67 , 68 ]. Even among older adults without diagnosed neurological disorders, the Timed Up and Go and the Berg Balance Scale demonstrate insufficient diagnostic accuracy to categorize fallers versus non-fallers, making them inadequate as standalone assessments for determining fall risk [ 23 , 69 ]. Secondly, the complexity of balance impairment in stroke survivors extends beyond motor function. It also includes perceptual and cognitive impairments [ 70 ], which may limit the effectiveness of the Timed Up and Go and the Berg Balance Scale, as they focus only on general balance and mobility. Lastly, these tests fail to address the underlying mechanisms necessary for maintaining balance [ 71 ], specifically the contributions of the visual, vestibular, and proprioceptive systems [ 72 ]. Stroke survivors experience damage to all three sensory systems, with proprioception being affected in 11-85% of the stroke patient population [ 73 , 74 ]. Therefore, without evaluating these distinct sensory systems, clinicians cannot identify the nature of the balance deficit or understand which specific postural control mechanism is compromised [ 75 ]. Our subgroup analysis found no significant difference between the Timed Up and Go test and the Berg Balance Scale in accurately categorizing fall risk (Qₘ = 0.002, p = 0.963). This means that clinicians face the same challenge with both tests – choosing one test over the other will not impact their diagnostic accuracy. Our meta-regression examining the cut-off values from both tests showed no significant moderation, suggesting that modifying the threshold values may not improve the ability of these tests to accurately categorize fall risk in stroke survivors. Moreover, the considerable variability in the cut-offs - ranging from 14 to 25 seconds for the Timed Up and Go test and from 19 to 50.5 for the Berg Balance Scale (see Table 1 ) – reflects a concerning lack of standardization across studies and represents a significant question regarding how clinicians are assessing and categorizing fall risk in stroke survivors. It is worth noting that the absence of heterogeneity in our meta-analysis (τ ² = 0.000; I² = 0%) suggests consistency in these findings across the included studies. The Egger’s weighted test (t (20) = 0.024, p = 0.981) and the rank correlation test (τ = -0.030, p = 0.867) demonstrated an absence of publication bias in the included studies. Additionally, our leave-one-out sensitivity analysis, which systematically removed each study individually to evaluate its impact on the overall results, confirmed that no single study has a significant influence on the pooled effect, further strengthening the robustness of our findings. Despite our comprehensive search using multiple databases, we identified only 15 eligible studies, which may limit the generalizability of our findings. This relatively small sample size may have affected our statistical power to detect a significant association and therefore, its interpretation requires careful consideration. Additionally, of the four most commonly used fall risk assessments, we could not assess the 6-minute walk test and 10-meter walk test because there were not enough studies that addressed their diagnostic accuracy in stroke survivors. CONCLUSION In summary, this systematic review and meta-analysis found evidence of a negative association between the Timed Up and Go test and the Berg Balance Scale and their ability to accurately identify fall risk in stroke survivors. However, this finding was not statistically significant. The absence of heterogeneity across studies (I² = 0%) suggests that this finding is worth consideration despite its non-significance. Moreover, our findings raise important concerns about how these widely used tests are applied in clinical practice to categorize fall risk in stroke survivors, particularly given the considerable variability in cut-off values observed across studies, which reflects the lack of standardized assessments and cut-off values across CPGs. Future research should focus on developing or implementing a stroke-specific fall risk assessment that is objective, sensitive, and tailored to the underlying mechanisms of fall risk in stroke survivors, with appropriate cut-off values. Improving the accuracy of fall risk assessments could significantly enhance fall prevention strategies and rehabilitation care. Data Availability All data produced in the present study are available upon reasonable request to the authors. CONFLICT OF INTEREST All authors declare no conflict of interest. ACKNOWLEDGMENTS The authors would like to thank Mr. Santamaria Guzman, for serving as the second reviewer during the data screening process and the Auburn University Librarians for their guidance throughout with the comprehensive literature search process. Non-standard Abbreviations and Acronyms CPGs clinical practice guidelines logOR natural logarithm of odds ratio OR odds ratio REML restricted maximum likelihood estimator TP true positives TN true negatives FP false positives FN false negatives TUG Timed Up and Go BBS Berg Balance Scale REFERENCES 1. ↵ Chohan SA , Venkatesh PK , How CH . Long-term complications of stroke and secondary prevention: an overview for primary care physicians . Singapore Med J . 2019 ; 60 ( 12 ): 616 – 620 . doi: 10.11622/smedj.2019158 . OpenUrl CrossRef PubMed 2. ↵ Benjamin EJ , Blaha MJ , Chiuve SE , Cushman M , Das SR , Deo R , de Ferranti SD , Floyd J , Fornage M , Gillespie C , Isasi CR , Jiménez MC , Jordan LC , Judd SE , Lackland D , Lichtman JH , Lisabeth L , Liu S , Longenecker CT , Mackey RH. , et al. Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association . Circulation. Cardiovascular imaging . 2017 ; 135 ( 10 ): e146 – e603 . doi: 10.1161/CIR.0000000000000485 . OpenUrl CrossRef 3. ↵ Denissen S , Staring W , Kunkel D , Pickering RM , Lennon S , Geurts AC , Weerdesteyn V , Verheyden GS . Interventions for Preventing Falls in People After Stroke . Stroke . 2020 ; 51 ( 3 ): e47 – e48 . doi: 10.1161/STROKEAHA.119.028157 . OpenUrl CrossRef PubMed 4. Awosika OO , Garver A , Drury C , Sucharew HJ , Boyne P , Schwab SM , Wasik E , Earnest M , Dunning K , Bhattacharya A , Khatri P , Kissela BM . Insufficiencies in sensory systems reweighting is associated with walking impairment severity in chronic stroke: an observational cohort study . Front Neurol . 2023 ; 3 ( 14 ): 1244657 . doi: 10.3389/fneur.2023.1244657 . OpenUrl CrossRef 5. Arienti C , Lazzarini SG , Pollock A , Negrini S . Rehabilitation interventions for improving balance following stroke: An overview of systematic reviews . PLoS One . 2019 ; 14 ( 7 ): e0219781 . doi: 10.1371/journal.pone.0219781 . OpenUrl CrossRef PubMed 6. Smania N , Picelli A , Gandolfi M . Rehabilitation of sensorimotor integration deficits in balance impairment of patients with stroke hemiparesis: a before/after pilot study . Neurol Sci . 2008 ; 29 : 313 – 319 . doi: 10.1007/s10072-008-0988-0 . OpenUrl CrossRef PubMed Web of Science 7. ↵ Jang SH , Lee JH . Impact of sensory integration training on balance among stroke patients: sensory integration training on balance among stroke patients . Open Medicine (Wars) . 2016 ; 11 ( 1 ): 330 – 335 . doi: 10.1515/med-2016-0061 . OpenUrl CrossRef 8. ↵ Abdollahi M , Whitton N , Zand R , Dombovy M , Parnianpour M , Khalaf K , Rashedi E . A Systematic Review of Fall Risk Factors in Stroke Survivors: Towards Improved Assessment Platforms and Protocols . Front Bioeng Biotechnol . 2022 ; 10 : 910698 . doi: 10.3389/fbioe.2022.910698 . OpenUrl CrossRef 9. ↵ Homann B , Plaschg A , Grundner M , Haubenhofer A , Griedl T , Ivanic G , Hofer E , Fazekas F , Homann CN . The impact of neurological disorders on the risk for falls in the community dwelling elderly: a case-controlled study . BMJ Open . 2013 ; 3 ( 11 ): e003367 . doi: 10.1136/bmjopen-2013-003367 . OpenUrl Abstract / FREE Full Text 10. ↵ Khan F , Abusharha S , Alfuraidy A , Nimatallah K , Almalki R , Basaffar R , Mirdad M , Chevidikunnan MF , Basuodan R . Prediction of Factors Affecting Mobility in Patients with Stroke and Finding the Mediation Effect of Balance on Mobility: A Cross-Sectional Study . Int J Environ Res Public Health . 2022 ; 19 ( 24 ): 16612 . doi: 10.3390/ijerph192416612 . OpenUrl CrossRef PubMed 11. ↵ Chen K , Zhu S , Tang Y , Lan F , Liu Z . Advances in balance training to prevent falls in stroke patients: a scoping review . Frontiers in neurology . 2024 ; 15 : 1167954 . doi: 10.3389/fneur.2024.1167954 . OpenUrl CrossRef 12. ↵ Breisinger TP , Skidmore ER , Niyonkuru C , Terhorst L , Campbell GB . The Stroke Assessment of Fall Risk (SAFR): predictive validity in inpatient stroke rehabilitation . Clin Rehabil . 2014 ; 28 ( 12 ): 1218 – 1224 . doi: 10.1177/0269215514534276 . OpenUrl CrossRef PubMed 13. ↵ Khan F , Chevidikunnan MF . Prevalence of Balance Impairment and Factors Associated with Balance among Patients with Stroke . A Cross Sectional Retrospective Case Control Study. Healthcare . 2021 ; 9 ( 3 ): 320 . doi: 10.3390/healthcare9030320 . OpenUrl CrossRef PubMed 14. ↵ Organisation ., European Stroke . Falls After a Stroke . 2019 ; Available from: https://eso-stroke.org/falls-after-a-stroke/#:~:text=Importantly%2C%20a%20higher%20proportion%20of%20those%20with%20stroke,falls%20and%20overall%20numbers%20of%20people%20falling.%2014 . 15. ↵ Abdollahi M , Rashedi E , Jahangiri S , Kuber PM , Azadeh-Fard N , Dombovy M . Fall Risk Assessment in Stroke Survivors: A Machine Learning Model Using Detailed Motion Data from Common Clinical Tests and Motor-Cognitive Dual-Tasking . Sensors . 2024 ; 24 ( 3 ): 812 . doi: 10.3390/s24030812 . OpenUrl CrossRef PubMed 16. ↵ Dos Santos RB , Fiedler A , Badwal A , Legasto-Mulvale JM , Sibley KM , Olaleye OA , Diermayr G , Salbach NM . Standardized tools for assessing balance and mobility in stroke clinical practice guidelines worldwide: A scoping review . Front Rehabil Sci . 2023 ; 4 : 1084085 . doi: 10.3389/fresc.2023.1084085 . OpenUrl CrossRef 17. Moore JL , Potter K , Blankshain K , Kaplan SL , O’Dwyer LC , Sullivan JE . A Core Set of Outcome Measures for Adults With Neurologic Conditions Undergoing Rehabilitation: A CLINICAL PRACTICE GUIDELINE . Journal of neurologic physical therapy : JNPT . 2018 ; 42 ( 3 ): 174 – 220 . doi: 10.1097/NPT.0000000000000229 . OpenUrl CrossRef PubMed 18. Kirshner B , Guyatt G . A methodological framework for assessing health indices . Journal of chronic diseases . 1985 ; 38 ( 1 ): 27 – 36 . doi: 10.1016/0021-9681(85)90005-0 . OpenUrl CrossRef PubMed Web of Science 19. ↵ Salvalaggio S , Boccuni L , Turolla , A . Patient’s assessment and prediction of recovery after stroke: a roadmap for clinicians . Archives of physiotherapy . 2023 ; 13 ( 1 ): 13 . doi: 10.1186/s40945-023-00167-4 . OpenUrl CrossRef PubMed 20. ↵ Agyenkwa SK , Yarfi C , Banson AN , Kofi-Bediako WA , Abonie US , Angmorterh SK , Ofori EK . Assessing the Use of Standardized Outcome Measures for Stroke Rehabilitation among Physiotherapists in Ghana . Stroke research and treatment . 2020 ; 2020: 9259017 . doi: 10.1155/2020/9259017 . OpenUrl CrossRef 21. ↵ Montero-Odasso M , van der Velde N , Martin FC , Petrovic M , Tan MP , Ryg J , Aguilar-Navarro S , Alexander NB , Becker C , Blain H , Bourke R , Cameron ID , Camicioli R , Clemson L , Close J , Delbaere K , Duan L , Duque G , Dyer SM , Freiberger E . World guidelines for falls prevention and management for older adults: a global initiative . Age and ageing . 2022 ; 51 ( 9 ) doi: 10.1093/ageing/afac205 . OpenUrl CrossRef PubMed 22. ↵ Harris JE , Eng JJ , Marigold DS , Tokuno CD , Louis CL . Relationship of balance and mobility to fall incidence in people with chronic stroke . Physical therapy . 2005 ; 85 ( 2 ): 150 – 158 . doi: 10.1093/ptj/85.2.150 . OpenUrl Abstract / FREE Full Text 23. ↵ Barry E , Galvin R , Keogh C , Horgan F , Fahey T . Is the Timed Up and Go test a useful predictor of risk of falls in community dwelling older adults: a systematic review and meta-analysis . BMC Geriatr . 2014 ; 1 ( 14 ) doi: 10.1186/1471-2318-14-14 . OpenUrl CrossRef PubMed 24. ↵ Akobeng , AK . Understanding diagnostic tests 1: sensitivity, specificity and predictive values . Acta paediatrica . 2007 ; 96 ( 3 ): 338 – 341 . doi: 10.1111/j.1651-2227.2006.00180.x . OpenUrl CrossRef PubMed Web of Science 25. ↵ Lalkhen AG , McCluskey A . Clinical tests: sensitivity and specificity . Continuing Education in Anaesthesia Critical Care & Pain . 2008 ; 8 ( 6 ): 221 – 223 . doi: 10.1093/bjaceaccp/mkn041 . OpenUrl CrossRef 26. ↵ Pimenta C , Correia A , Alves M , Virella D . Assessing the risk for falls among Portuguese community-dwelling stroke survivors. Are we using the better tools? Observational study. Porto biomedical journal . 2022 ; 7 ( 3 ): e160 . doi: 10.1097/j.pbj.0000000000000160 . OpenUrl CrossRef PubMed 27. ↵ Lafontant K , Blount A , Suarez JRM , Fukuda DH , Stout JR , Trahan EM , Lighthall NR , Park JH , Xie R , Thiamwong L. Comparing Sensitivity, Specificity, and Accuracy of Fall Risk Assessments in Community-Dwelling Older Adults . Clin Interv Aging . 2024 ; 19 : 581 – 588 . doi: 10.2147/CIA.S453966 . OpenUrl CrossRef PubMed 28. ↵ Hauer K , Schwenk M , Englert S , Zijlstra R , Tuerner S , Dutzi I . Mismatch of Subjective and Objective Risk of Falling in Patients with Dementia . Journal of Alzheimer’s disease: JAD . 2020 ; 78 ( 2 ): 557 – 572 . doi: 10.3233/JAD-200572 . OpenUrl CrossRef 29. ↵ Blum L , Korner-Bitensky N . Usefulness of the Berg Balance Scale in stroke rehabilitation: a systematic review . Physical therapy . 2008 ; 88 ( 5 ): 559 – 566 . doi: 10.2522/ptj.20070205 . OpenUrl Abstract / FREE Full Text 30. Regan E , Middleton A , Stewart JC , Wilcox S , Pearson JL , Fritz S . The six-minute walk test as a fall risk screening tool in community programs for persons with stroke: a cross-sectional analysis . Topics in stroke rehabilitation . 2020 ; 27 ( 2 ): 118 – 126 . doi: 10.1080/10749357.2019.1667657 . OpenUrl CrossRef PubMed 31. ↵ Cheng DK , Nelson M , Brooks D , Salbach NM . Validation of stroke-specific protocols for the 10-meter walk test and 6-minute walk test conducted using 15-meter and 30-meter walkways . Topics in stroke rehabilitation . 2020 ; 27 ( 4 ): 251 – 261 . doi: 10.1080/10749357.2019.1691815 . OpenUrl CrossRef PubMed 32. ↵ Maeda N , Urabe Y , Murakami M , Itotani K , Kato J . Discriminant analysis for predictor of falls in stroke patients by using the Berg Balance Scale . Singapore medical journal . 2015 ; 56 ( 5 ): 280 – 283 . doi: 10.11622/smedj.2015033 . OpenUrl CrossRef PubMed 33. ↵ Chan PP , Si Tou JI , Tse MM , Ng SS . Reliability and Validity of the Timed Up and Go Test With a Motor Task in People With Chronic Stroke . Archives of physical medicine and rehabilitation . 2017 ; 98 : 2213 – 2220 . doi: 10.1016/j.apmr.2017.03.008 . OpenUrl CrossRef PubMed 34. ↵ Page MJ , McKenzie JE , Bossuyt PM , Boutron I , Hoffmann TC , Mulrow CD , Shamseer L , Tetzlaff JM , Akl EA , Brennan SE , Chou R , Glanville J , Grimshaw JM , Hróbjartsson A , Lalu MM , Li T , Loder EW , Mayo-Wilson E , McDonald S , McGuinness LA , Stewart LA , Thomas J , Tricco AC , Welch VA , Whiting P , Moher D. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews . BMJ (Clinical research ed .). 2021 ; 372 ( 71 ) doi: 10.1136/bmj.n71 . OpenUrl FREE Full Text 35. ↵ Parikh R , Mathai A , Parikh S , Chandra Sekhar G , Thomas R . Understanding and using sensitivity, specificity and predictive values . Indian journal of ophthalmology . 2008 ; 56 ( 1 ): 45 – 50 . doi: 10.4103/0301-4738.37595 . OpenUrl CrossRef PubMed 36. ↵ Doi SA , Furuya-Kanamori L , Xu C , Lin L , Chivese T , Thalib L. Controversy and Debate: Questionable utility of the relative risk in clinical research: Paper 1: A call for change to practice . Journal of clinical epidemiology . 2022 ; 142 : 271 – 279 . doi: 10.1016/j.jclinepi.2020.08.019 . OpenUrl CrossRef PubMed 37. ↵ Szumilas , M . Explaining odds ratios . Journal of the Canadian Academy of Child and Adolescent Psychiatry . 2010 ; 19 ( 3 ): 227 – 229 . OpenUrl CrossRef Web of Science 38. ↵ Adlou B , Wilson A , Wilburn C , Weimar W. Early sport specialization impact on rates of injury in collegiate and professional sport participation: A systematic review and meta-analysis . international Journal of Sports Science & Coaching . 2024 ; 19 ( 4 ): 1833 – 1843 . doi: 10.1177/17479541241248565 OpenUrl CrossRef 39. ↵ Higgins JP , Thompson SG , Deeks JJ , Altman DG . Measuring inconsistency in meta-analyses . BMJ (Clinical research ed.). 2003 ; 327 ( 7414 ): 557 – 560 . doi: 10.1136/bmj.327.7414.557 . OpenUrl FREE Full Text 40. ↵ Deeks JJ , Higgins JPT , Altman DG. , Analysing Data and Undertaking Meta-Analyses . , in Cochrane Handbook for Systematic Reviews of Interventions . 2019 . p. 241 – 284 . 41. ↵ Ariel de Lima D , Helito CP , de Lima LL , Clazzer R , Gonçalves RK , de Camargo OP . HOW TO PERFORM A META-ANALYSIS: A PRACTICAL STEP-BY-STEP GUIDE USING R SOFTWARE AND RSTUDIO . Acta ortopedica brasileira . 2022 ; 30 ( 3 ): e248775 . doi: 10.1590/1413-785220223003e248775 . OpenUrl CrossRef 42. ↵ Ashburn A , Hyndman D , Pickering R , Yardley L , Harris S . Predicting people with stroke at risk of falls . Age and Ageing . 2008 ; 37 ( 3 ): 270 – 276 . doi: 10.1093/ageing/afn066 . OpenUrl CrossRef PubMed Web of Science 43. Beninato M , Portney LG , Sullivan PE . Using the International Classification of Functioning, Disability and Health as a framework to examine the association between falls and clinical assessment tools in people with stroke . Physical therapy . 2009 ; 89 ( 8 ): 816 – 825 . doi: 10.2522/ptj.20080160 . OpenUrl Abstract / FREE Full Text 44. Chinsongkram B , Chaikeeree N , Saengsirisuwan V , Viriyatharakij N , Horak FB , Boonsinsukh R . Reliability and validity of the Balance Evaluation Systems Test (BESTest) in people with subacute stroke . Physical therapy . 2014 ; 94 ( 11 ): 632 – 1643 . doi: 10.2522/ptj.20130558 . OpenUrl Abstract / FREE Full Text 45. Fiedorová I , Mrázková E , Zádrapová M , Tomášková H . Receiver Operating Characteristic Curve Analysis of the Somatosensory Organization Test, Berg Balance Scale, and Fall Efficacy Scale–International for Predicting Falls in Discharged Stroke Patients . International Journal of Environmental Research and Public Health . 2022 ; 19 ( 15 ): 9181 . doi: 10.3390/ijerph19159181 . OpenUrl CrossRef 46. Maeda N , Kato J , Shimada T . Predicting the probability for fall incidence in stroke patients using the Berg Balance Scale . The Journal of international medical research . 2009 ; 37 ( 3 ): 697 – 704 . doi: 10.1177/147323000903700313 . OpenUrl CrossRef PubMed 47. ↵ Sahin IE , Guclu-Gunduz A , Yazici G , Ozkul C , Volkan-Yazici M , Nazliel B , Tekindal MA . The sensitivity and specificity of the balance evaluation systems test-BESTest in determining risk of fall in stroke patients . Neurorehabilitation and neural repair . 2019 ; 44 ( 1 ): 67 – 77 . doi: 10.3233/NRE-182558 . OpenUrl CrossRef 48. ↵ Lee KB , Lee JS , Jeon IP , Choo DY , Baik MJ , Kim EH , Kim WS , Park CS , Kim JY , Shin YI , Bae JE , Kim JS . An analysis of fall incidence rate and risk factors in an inpatient rehabilitation unit: A retrospective study . Topics in stroke rehabilitation . 2021 ; 28 ( 2 ): 81 – 87 . doi: 10.1080/10749357.2020.1774723 . OpenUrl CrossRef PubMed 49. Pinto EB , Nascimento C , Marinho C , Oliveira I , Monteiro M , Castro M , Myllane-Fernandes P , Ventura LM , Maso I , Lopes AA , Oliveira-Filho J . Risk factors associated with falls in adult patients after stroke living in the community: baseline data from a stroke cohort in Brazil . Topics in stroke rehabilitation . 2014 ; 21 ( 3 ): 220 – 227 . doi: 10.1310/tsr2103-220 . OpenUrl CrossRef PubMed 50. ↵ Yang L , He C , Pang MY . Reliability and Validity of Dual-Task Mobility Assessments in People with Chronic Stroke . PloS one . 2016 ; 11 ( 1 ): e0147833 . doi: 10.1371/journal.pone.0147833 . OpenUrl CrossRef PubMed 51. ↵ Jalayondeja C , Sullivan PE , Pichaiyongwongdee S . Six-month prospective study of fall risk factors identification in patients post-stroke . Geriatrics & gerontology international . 2014 ; 14 ( 4 ): 778 – 785 . doi: 10.1111/ggi.12164 . OpenUrl CrossRef PubMed 52. Andersson AG , Kamwendo K , Seiger A , Appelros P . How to identify potential fallers in a stroke unit: validity indexes of 4 test methods . Journal of rehabilitation medicine . 2006 ; 38 ( 3 ): 186 – 19 . doi: 10.1080/16501970500478023 . OpenUrl CrossRef PubMed Web of Science 53. Lee G , An S , Lee Y , Park DS . Clinical measures as valid predictors and discriminators of the level of community ambulation of hemiparetic stroke survivors . Journal of physical therapy science . 2016 ; 28 ( 8 ): 2184 – 2189 . doi: 10.1589/jpts.28.2184 . OpenUrl CrossRef PubMed 54. Liu TW , Ng SSM . Assessing the fall risks of community-dwelling stroke survivors using the Short-form Physiological Profile Assessment (S-PPA) . . PloS one . 2019 ; 14 ( 5 ): e0216769 . doi: 10.1371/journal.pone.0216769 . OpenUrl CrossRef PubMed 55. Persson CU , Hansson PO , Sunnerhagen KS . Clinical tests performed in acute stroke identify the risk of falling during the first year: postural stroke study in Gothenburg (POSTGOT) . Journal of rehabilitation medicine . 2011 ; 43 ( 3 ): 348 – 353 . doi: 10.2340/16501977-0677 . OpenUrl CrossRef PubMed 56. ↵ Tsang CS , Liao LR , Chung RC , Pang MY . Psychometric properties of the Mini-Balance Evaluation Systems Test (Mini-BESTest) in community-dwelling individuals with chronic stroke . Physical therapy . 2013 ; 93 ( 8 ): 1102 – 1115 . doi: 10.2522/ptj.20120454 . OpenUrl Abstract / FREE Full Text 57. ↵ Ospel J , Singh N , Ganesh A , Goyal M . Sex and Gender Differences in Stroke and Their Practical Implications in Acute Care . Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association . 2023 ; 25 ( 1 ): 16 – 25 . doi: 10.5853/jos.2022.04077 . OpenUrl CrossRef 58. ↵ Reeves MJ , Bushnell , CD , Howard G , Gargano JW , Duncan PW , Lynch G , Khatiwoda A , Lisabeth L . Sex differences in stroke: epidemiology, clinical presentation, medical care, and outcomes . The Lancet. Neurology . 2008 ; 7 ( 10 ): 915 – 926 . doi: 10.1016/S1474-4422(08)70193-5 . OpenUrl CrossRef PubMed Web of Science 59. ↵ Osawa A , Maeshima S. , Unilateral Spatial Neglect Due to Stroke . Stroke [Internet] , ed. D. S. 2021 , Brisbane (AU) : Exon Publications . 60. ↵ Peters S , Handy TC , Lakhani B , Boyd LA , Garland SJ . Motor and Visuospatial Attention and Motor Planning After Stroke: Considerations for the Rehabilitation of Standing Balance and Gait . Physical therapy . 2015 ; 95 ( 10 ): 1423 – 1432 . doi: 10.2522/ptj.20140492 . OpenUrl Abstract / FREE Full Text 61. ↵ Batchelor FA , Mackintosh SF , Said CM , Hill KD . Falls after stroke . International journal of stroke : official journal of the International Stroke Society . 2012 ; 7 ( 6 ): 482 – 490 . doi: 10.1111/j.1747-4949.2012.00796.x . OpenUrl CrossRef PubMed Web of Science 62. Weerdesteyn V , de Niet M , van Duijnhoven HJ , Geurts AC . Falls in individuals with stroke . J Rehabil Res Dev . . 2008 ; 45 ( 8 ): 1195 – 1213 . OpenUrl CrossRef PubMed Web of Science 63. Alenazi AM , Alshehri MM , Alothman S , Rucker J , Dunning K , D’Silva LJ , Kluding PM . Functional Reach, Depression Scores, and Number of Medications Are Associated With Number of Falls in People With Chronic Stroke . PM & R : the journal of injury, function, and rehabilitation . 2018 ; 10 ( 8 ): 806 – 816 . doi: 10.1016/j.pmrj.2017.12.005 . OpenUrl CrossRef 64. ↵ Divani AA , Vazquez G , Barrett AM , Asadollahi M , Luft AR . Risk factors associated with injury attributable to falling among elderly population with history of stroke . Stroke . 2009 ; 40 ( 10 ): 3286 – 3292 . doi: 10.1161/STROKEAHA.109.559195 . OpenUrl Abstract / FREE Full Text 65. ↵ Liao WL , Chang CW , Sung PY , Hsu WN , Lai MW , Tsai SW . The Berg Balance Scale at Admission Can Predict Community Ambulation at Discharge in Patients with Stroke. Medicina (Kaunas , Lithuania) . 2021 ; 57 ( 6 ): 556 . doi: 10.3390/medicina57060556 . OpenUrl CrossRef 66. ↵ Persson CU , Danielsson A , Sunnerhagen KS , Grimby-Ekman A , Hansson PO . Timed Up & Go as a measure for longitudinal change in mobility after stroke - Postural Stroke Study in Gothenburg (POSTGOT) . Journal of neuroengineering and rehabilitation . 2014 ; 11 ( 83 ) doi: 10.1186/1743-0003-11-83 . OpenUrl CrossRef PubMed 67. ↵ Blum L , Korner-Bitensky N . Usefulness of the Berg Balance Scale in Stroke Rehabilitation: A Systematic Review . Physical Therapy . 2008 ; 88 ( 1 ): 559 – 56 . doi: 10.2522/ptj.20070205 . OpenUrl Abstract / FREE Full Text 68. ↵ Berg KO , Wood-Dauphinee SL , Williams JI , Maki B . Measuring balance in the elderly: validation of an instrument . Can J Public Health . 1992 69. ↵ Lima CA , Ricci NA , Nogueira EC , Perracini MR . The Berg Balance Scale as a clinical screening tool to predict fall risk in older adults: a systematic review . Physiotherapy Canada . 2018 ; 104 ( 4 ): 383 – 394 . doi: 10.1016/j.physio.2018.02.002 . OpenUrl CrossRef 70. ↵ VanGilder JL , Hooyman A , Peterson DS , Schaefer SY . Post-stroke cognitive impairments and responsiveness to motor rehabilitation: A review . Current physical medicine and rehabilitation reports . 2020 ; 8 ( 4 ): 461 – 468 . doi: 10.1007/s40141-020-00283-3 . OpenUrl CrossRef 71. ↵ Rose DJ , Lucchese N , Wiersma LD . Development of a multidimensional balance scale for use with functionally independent older adults . Archives of physical medicine and rehabilitation . 2006 ; 87 ( 11 ): 1478 – 1485 . doi: 10.1016/j.apmr.2006.07.263 . OpenUrl CrossRef PubMed Web of Science 72. ↵ Chagdes JR , Rietdyk S , Haddad JM , Zelaznik HN , Raman A , Rhea CK , Silver TA . Multiple timescales in postural dynamics associated with vision and a secondary task are revealed by wavelet analysis . Exp Brain Res . 2009 ; 197 ( 3 ): 297 – 310 . doi: 10.1007/s00221-009-1915-1 . OpenUrl CrossRef PubMed 73. ↵ Chae SH , Kim YL , Lee SM . Effects of phase proprioceptive training on balance in patients with chronic stroke . Journal of physical therapy science . 2017 ; 29 ( 5 ): 839 – 844 . doi: 10.1589/jpts.29.839 . OpenUrl CrossRef PubMed 74. ↵ Xu J , Witchalls J , Preston E , Pan L , Zhang G , Waddington G , … Han J . Relationship of ankle proprioception measured in weight bearing with balance and walking ability in people with stroke: a cross-sectional study . Topics in Stroke Rehabilitation . 2025 : 1 – 10 . doi: 10.1080/10749357.2025.2469472 . OpenUrl CrossRef 75. ↵ Mancini M , Horak FB . The relevance of clinical balance assessment tools to differentiate balance deficits . Eur J Phys Rehabil Med . 2010 ; 46 ( 2 ): 239 – 48 . OpenUrl PubMed View the discussion thread. Back to top Previous Next Posted June 16, 2025. Download PDF Data/Code Email Thank you for your interest in spreading the word about medRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. 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Evaluating the Accuracy of Common Clinical Fall Risk Assessments in Stroke Survivors: A Systematic Review and Meta-Analysis Marina Meyer-Vega , Nojan Valadi , Daniel J. Goble , Niyati Baweja , Harsimran S. 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