Experience of our clinic in intrauterine insemination cycles made with microfluidic sperm sorting chips

Determination of the clinical pregnancy rate in intrauterine insemination (IUI) cycles performed with microfluidic sperm sorting chips.

In Giresun University Obstetrics and Pediatrics Hospital Infertility Clinic, 133 patients who underwent IUI after ovarian stimulation with gonadotropins in unexplained infertility, mild to moderate male factor, ovulatory dysfunction, mild endometriosis were retrospectively analyzed between January 2016-January 2020. Microfluidic sperm sorting chip was used for sperm preparation.

The number of cycles was found to be 133. Mean female age was; 29.9±4.7 years, mean total motile sperm count was; 72.9±63.7 million, mean antral follicle count was; 18.1±10.1, the mean total gonadotropin dose used was 897.6±366 IU. Considering the causes of infertility; 54.1% unexplained, 8.3% mild male factor, 31.6% polycystic ovary syndrome (PCOS) and 6% endometriosis. The clinical pregnancy rate was found to be 19.5% (26/133).

Microfluidic sperm sorting chips provide an increase in clinical pregnancy rates compared to conventional methods in IUI cycles and allow for a practical and rapid sperm preparation. Key Words: IUI, microfluidic sperm sorting chip, clinical pregnancy rate. Downloads Published Issue Section License Copyright (c) 2021 Mehmet Sipahi, Şebnem Alanya Tosun, Sadettin Oguzhan Tutar This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. AEJOG is an open-access journal which means that through the internet; freely accessible, readable, downloaded, copied, distributed, printed, scanned, linked to full texts, indexed, transferred to the software as data and used for any legal purpose, without financial, legal and technical obstacles. The only authority on reproduction and distribution and the sole copyright role in this field; has been given to authors therefore they can have control over the integrity of their work, so that they are properly recognized and cited. This is in accordance with the BOAI definition of open access. The content in Aegean Journal of Obstetrics and Gynecology (AEJOG) is protected by copyright. All copyrights of the submitted articles are transferred to the Aegean Journal of Obstetrics and Gynecology within the national and international regulations at the beginning of the evaluation process. Upon submission of their article, authors are requested to complete an assignment of copyright release form. Authors should acknowledge that they will not submit their manuscript to another journal, publish in any other language, or allow a third party to use the article without the written consent of the Aegean Journal of Obstetrics and Gynecology. When an article is published on AEJOG, it is read and reused for free as soon as it is published under a Creative Commons Attribution-NonCommercial 4.0 (CC BY NC 4.0) license. In case the article is rejected, all copyrights are given back to the authors. The content of the article and all legal proceedings against the journal, if any, are the responsibility of the author. In addition, all financial and legal liability for the copyright of the presented tables, figures and other visual materials protected by law belongs to the authors. It is the responsibility of the corresponding author to report authors scientific contributions and responsibilities regarding the article. In case of any conflict of interest, it is the responsibility of the authors to indicate the conflict of interest in the Disclosure part of the article. Author names will be published as they are listed on the submitted Title page.