Experience of our clinic in intrauterine insemination cycles made with microfluidic sperm sorting chips

Mehmet Sipahi, Şebnem Alanya Tosun, Sadettin Oğuzhan Tutar
In: Aegean Journal of Obstetrics and Gynecology · 2021 · vol. 3(1) , pp. 15–18 · doi:10.46328/aejog.v3i1.81 · W3148161465
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Abstract

Objective: Determination of the clinical pregnancy rate in intrauterine insemination (IUI) cycles performed with microfluidic sperm sorting chips. Material and Methods: In Giresun University Obstetrics and Pediatrics Hospital Infertility Clinic, 133 patients who underwent IUI after ovarian stimulation with gonadotropins in unexplained infertility, mild to moderate male factor, ovulatory dysfunction, mild endometriosis were retrospectively analyzed between January 2016-January 2020. Microfluidic sperm sorting chip was used for sperm preparation. Results: The number of cycles was found to be 133. Mean female age was; 29.9±4.7 years, mean total motile sperm count was; 72.9±63.7 million, mean antral follicle count was; 18.1±10.1, the mean total gonadotropin dose used was 897.6±366 IU. Considering the causes of infertility; 54.1% unexplained, 8.3% mild male factor, 31.6% polycystic ovary syndrome (PCOS) and 6% endometriosis. The clinical pregnancy rate was found to be 19.5% (26/133). Conclusion: Microfluidic sperm sorting chips provide an increase in clinical pregnancy rates compared to conventional methods in IUI cycles and allow for a practical and rapid sperm preparation. Key Words: IUI, microfluidic sperm sorting chip, clinical pregnancy rate.

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endometriosisinfertility

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