Pituitary gonadotrophins and prolactin in patients with endometrial cancer, fibroids or ovarian tumours

Olavi Ylikorkala, O Ylikorkala, A Kauppila, Antti Kauppila, T. Rajala
British journal of obstetrics and gynaecology · 1979 · vol. 86(11) , pp. 901–904 · doi:10.1111/j.1471-0528.1979.tb10721.x · PMID:116672 · W1993072481
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Serum levels of FSH, LH, and prolactin were measured in patients with gynecological tumors and controls, revealing low FSH and excessive prolactin response only in women with fibroids.

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Abstract

The serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH) and, prolactin (PRL) were measured before and after gonadotrophin releasing hormone (GnRH) and thyrotrophin releasing hormone (TRH) stimulation in 17 patients with endometrial cancer, in 15 patients with uterine fibroids, in 11 patients with ovarian cystadenomas or cancer and in 14 age-matched controls. The women with fibroids had a low FSH level and a diminished FSH response to GnRH but an excessive PRL response to TRH while the other patient groups did not differ from the controls. The results indicate no relation between pituitary function and endometrial or ovarian tumor.

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MeSH descriptors

Cystadenoma Gonadotropins, Pituitary Leiomyoma Ovarian Neoplasms Uterine Neoplasms Cystadenoma Female Follicle Stimulating Hormone Follicle Stimulating Hormone Gonadotropins, Pituitary Humans Leiomyoma Luteinizing Hormone Luteinizing Hormone Middle Aged Ovarian Neoplasms Pituitary Hormone-Releasing Hormones Prolactin Prolactin Thyrotropin-Releasing Hormone

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License: CC0 · commercial use OK