SULFONYLATED HETEROCYCLES USEFUL FOR MODULATION OF THE PROGESTERONE RECEPTOR

2008
OA: closed
⚙ AI-generated summary by qwen3.7-flash, 2026-09-17 ⓘ

Sulfonylated heterocycles are described as compounds useful for modulating the progesterone receptor to treat or prevent endometriosis, uterine leiomyomata, and other conditions.

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Abstract

Compounds of the following structure are provided, wherein n, R1-R3 and R6-R9 are defined below, as are methods of preparing and using these compounds for contraception; treating or preventing fibroids, uterine leiomyomata, endometriosis, dysfunctional bleeding, polycystic ovary syndrome, and hormone-dependent carcinomas; providing hormone replacement therapy; stimulating food intake; synchronizing estrus; and treating cycle-related symptoms.

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europepmc
last seen: 2026-10-24T06:12:55.650802+00:00