2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.
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Abstract
BackgroundThe American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health. The AHA Heart Disease and Stroke Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, brain health, complications of pregnancy, kidney disease, congenital heart disease, rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary heart disease, cardiomyopathy, heart failure, valvular disease, venous thromboembolism, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs).MethodsThe AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2025 AHA Statistical Update is the product of a full year's worth of effort in 2024 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members. This year's edition includes a continued focus on health equity across several key domains and enhanced global data that reflect improved methods and incorporation of ≈3000 new data sources since last year's Statistical Update.ResultsEach of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics.ConclusionsThe Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
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eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.
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- Early Mobilization Outcomes With Tenecteplase Treatment in Acute Ischemic Stroke (EMOTE-TNK) Study: Safety and Tolerability, Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 10, 3, (100711), (2026).https://doi.org/10.1016/j.mayocpiqo.2026.100711
- The dynamic journey of posttraumatic growth after acute myocardial infarction: A longitudinal qualitative study, International Journal of Nursing Studies, 178, (105384), (2026).https://doi.org/10.1016/j.ijnurstu.2026.105384
- Electric field-accelerated allosteric DNA-driven immune reaction for highly rapid and sensitive electrochemiluminescence detection of cMyBP-C protein, Biosensors and Bioelectronics, 302, (118542), (2026).https://doi.org/10.1016/j.bios.2026.118542
- Antiplatelet Drugs, Bleeding Disorders and Dentistry, (193-197), (2026).https://doi.org/10.1007/978-3-032-26713-9_25
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