Lipodermatosclerosis: Successful Treatment with Danazol

Christian Hafner, M.B. Wimmershoff, Michael Landthaler, Thomas Vogt
In: Acta Dermato-Venereologica · 2005 · vol. -1(1) , pp. 1 · doi:10.1080/00015550510027766 · PMID:16191868 · W1998408174
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This case report describes the successful treatment of lipodermatosclerosis, a sclerosing skin condition, using the weak androgen danazol.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This paper reports a successful treatment of lipodermatosclerosis using danazol, describing the approach and outcome in the affected patient(s). It is presented as a clinical report without an available abstract in the provided text, and the publication details do not indicate a controlled study design. The main finding is that danazol treatment was associated with resolution or improvement of lipodermatosclerosis. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Sir, Lipodermatosclerosis (LDS), also reported as liposclerosis, hypodermatitis sclerodermaformis, sclerosing panniculitis, pseudoscleroderma, indurated cellulitis, stasis panniculitis and chronic cellulitis, is characterized by a scleroderma-like induration of the skin and a typical ‘inverted champagne bottle’ sign. Although considerable progress has been made in understanding the pathophysiology, no unifying therapeutic concept exists and the efficiency of the various treatment options has been reported very controversially. In the present case we describe successful treatment of LDS with the weak androgen danazol.
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Lipodermatosclerosis: successful treatment with danazol DOI: https://doi.org/10.1080/00015550510027766Abstract No abstract availableDownloads Downloads Published How to Cite Issue Section License All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work. Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

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