AROMATASE INHIBITOR

A benzocycloalcane compound represented by general formula (I), wherein R represents hydrogen, C1-C4 lower alkoxy, nitro or C1-C4 lower alkoxycarbonyle; when X and Y represent each hydrogen or X and Y are combined together to represent oxygen, then Z represents hydrogen and the broken line represents an arbitrary bond; when X represents H, then Y and Z are combined together to represent a single bond; and n represents an integer of 0 or 1. This compound has a potent, selective aromatase-inhibiting effect and is useful as a remedy for estrogen-dependent cancers, such as breast, uterine or ovarian cancer, prostatomegaly, gynecomastia and endometriosis.