Study of Efficacy of Ormeloxifene in The Medical Management of Menorrhagia

Background: Selective Estrogen Receptive Modulators (SERM) like Ormeloxifene could be useful in DUB. Objective: To study efficacy of Ormeloxifene in medical management of menorrhagia. Methodology: 140 eligible participants were recruited for treatmentwith Ormeloxifeneover 1.5 years in a tertiary care hospital. Observations: Haemoglobin levels increased from pre-treatment (7.827 gm%) to post treatment (9.814 gm%); the mean increase being 1.98 gm%. Endometrial thickness decreased from 11.65mm to 7.39mm, with mean difference of 4.26mm. The median PBAC score pre-treatment was 106 (range- 168 to 70) & post-treatment was 63 (range- 84 to 36); the difference being highly significant (<0.01). Conclusion : Ormeloxifene is a highly efficacious drug for the medical management of menorrhagia.