Clear Cell Carcinoma of the Vulva Arising in Endometriosis.

Since Sampson first described the development of ovarian carcinoma in endometriosis in 1925, numerous case reports have documented the development of malignancies arising from foci of endometriosis. Clear cell carcinoma arising from endometriosis is very rare in the vulva. To date only two cases that originated in the vulva have been reported. We report a case of clear cell carcinoma in the vulva arising from endometriosis with a brief review of literatures.