Comparison of Bolus and Integrate Changes of Gray-scale During the Treatment of Adenomyosis with High Intensity Focused Ultrasound

Objective:To compare the efficacy of different gray-scale changes in adenomyosis treatment by high intensity focused ultrasound(HIFU).Methods:Retrospective analysis the gray-scale changes of 60 uterine adenomyosis patients treated with HIFU,compared the gray-scale changes with contrast MRI 1 day after treatment,analysis the relationship of different gray-scale changes compared with the treatment dosage,treatment time,intensity of treatment and non-contrast area of MRI.Results:There was no significant different of non-contrast area of contrast MRI between bolus and integrate changes of gray-scale(P0.05).The contrast MRI shows no statistic difference of ablation ratio,volume of ablation and treatment intensity between these two groups 1 day after the therapy procedure,however,the treatment dosage and treatment time of integrate gray-scale change group was much more than the bolus gray-scale change group(P0.05).There was no significant statistic difference of side effects between two groups(P0.05).Conclusions:This study shows that the integrate gray-scale changes can reflect the HIFU ablation efficacy of uterine adenomyosis.To reduce the risk of treatment,there were no necessary to get bolus gray-scale changes during the therapy.