Subcutaneous endometrial deposit: an unusual cause of right iliac fossa pain

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AI-generated summary by claude@2026-06, 2026-06-07

This study describes a 35-year-old woman whose right iliac fossa pain and palpable nodule, exacerbated by menses, were diagnosed as a subcutaneous endometrioma via ultrasound, CT, and biopsy.

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AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text

This case report describes a 35-year-old woman with a 7-day worsening and 7-month history of intermittent right iliac fossa pain accompanied by a palpable nodule that enlarged and became tender during menses, with a prior caesarean section 12 months earlier. Imaging using high-frequency ultrasound and contrast-enhanced CT identified a ~2 cm subcutaneous anterior abdominal wall nodule superficial to the right rectus abdominus, with a single vascular pedicle on Doppler and minimal surrounding fat stranding; the ultrasound and CT features prompted a broad differential including hematoma, abscess, sebaceous cyst, enlarged lymph node, desmoid tumor, and malignancies. A percutaneous ultrasound-guided biopsy confirmed the nodule as an endometrioma. This paper is centrally about endometriosis — it reports an unusual presentation of a subcutaneous endometrial deposit causing right iliac fossa pain and diagnosed as an endometrioma.

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Abstract

A 35-year-old woman presented to hospital with a 7-day history of worsening right iliac fossa pain. The patient reported a 7-month history of intermittent right iliac fossa pain, associated with a palpable nodule in the right iliac fossa. This nodule showed apparent increase in size and tenderness, on palpation, during her menses. Twelve months previously, the patient had undergone a caesarean section. Plain film of the abdomen was unremarkable. Ultrasound examination using a high frequency probe (7.5 MHz) showed a 2 cm nodule in the subcutaneous fat of the anterior abdominal wall superficial to the right rectus abdominus musculature which was hypoechoic relative to adjacent subcutaneous fat and of inhomogenous echotexture with low level internal hyperechoic echoes. Doppler interrogation showed a single vascular pedicle entering the mass at the periphery (Figure 1a). The margins were slightly irregular. There were no ultrasound features of incisional hernia. Computed tomography with intravenous and oral contrast revealed a 2 cm solid, slightly spiculated nodule, located in the subcutaneous fat without involvement of the anterior abdominal wall musculature and parallel to the Pfannensteil incision (Figure 1b). The nodule was hyperdense compared to rectus abdominus musculature following intravenous contrast enhancement, measuring approximately 80 Hounsfield units. There was minimal stranding of the surrounding subcutaneous fat. Differential diagnosis included haematoma, abscess, sebaceous cyst, enlarged lymph node, desmoid tumour, and malignant tumours such as malignant melanoma, or metastatic breast or renal cell carcinoma. Percutaneous biopsy using a 17 gauge coaxial needle system was performed under ultrasound guidance (Figure 2a). Histopathological examination confirmed endometrioma (Figure 2b).
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British Journal of Hospital Medicine (BJHM) is published by IMR Press from Volume 87 Issue 1 (2026). Previous articles were published by another publisher under the hybrid model (CC-BY-NC license or on a subscription basis), and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement. Subcutaneous endometrial deposit: an unusual cause of right iliac fossa pain Philip A Hodnett 1, Sean E McSweeney 1, Conor Bogue 2, Denis Kelly 3, H Paul Redmond 3, Michael M Maher 3 Affiliations Article Info 1 Radiology, Cork University Hospital, Cork, Ireland 2 The Hospital for Sick Children, University of Toronto, Canada, 3 Cork University Hospital, Cork, Ireland Abstract A 35-year-old woman presented to hospital with a 7-day history of worsening right iliac fossa pain. The patient reported a 7-month history of intermittent right iliac fossa pain, associated with a palpable nodule in the right iliac fossa. This nodule showed apparent increase in size and tenderness, on palpation, during her menses. Twelve months previously, the patient had undergone a caesarean section. Plain film of the abdomen was unremarkable. Ultrasound examination using a high frequency probe (7.5 MHz) showed a 2 cm nodule in the subcutaneous fat of the anterior abdominal wall superficial to the right rectus abdominus musculature which was hypoechoic relative to adjacent subcutaneous fat and of inhomogenous echotexture with low level internal hyperechoic echoes. Doppler interrogation showed a single vascular pedicle entering the mass at the periphery (Figure 1a). The margins were slightly irregular. There were no ultrasound features of incisional hernia. Computed tomography with intravenous and oral contrast revealed a 2 cm solid, slightly spiculated nodule, located in the subcutaneous fat without involvement of the anterior abdominal wall musculature and parallel to the Pfannensteil incision (Figure 1b). The nodule was hyperdense compared to rectus abdominus musculature following intravenous contrast enhancement, measuring approximately 80 Hounsfield units. There was minimal stranding of the surrounding subcutaneous fat. Differential diagnosis included haematoma, abscess, sebaceous cyst, enlarged lymph node, desmoid tumour, and malignant tumours such as malignant melanoma, or metastatic breast or renal cell carcinoma. Percutaneous biopsy using a 17 gauge coaxial needle system was performed under ultrasound guidance (Figure 2a). Histopathological examination confirmed endometrioma (Figure 2b).

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Flank Pain Soft Tissue Neoplasms Adult Diagnosis, Differential Endometriosis Endometriosis Female Flank Pain Humans Soft Tissue Neoplasms Soft Tissue Neoplasms Ultrasonography

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