PENGARUH HYPERBARIC OXYGEN (HBO) TERHADAP EKSPRESI HYPOXIA INDUCED FACTOR-1 ALPHA (HIF-1 ALPHA), VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) DAN LUAS JARINGAN ENDOMETRIOTIK PADA MENCIT MODEL ENDOMETRIOSIS
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Abstract
Hipoksia pada endometriosis akan meningkatkan ekspresi Hypoxia Inducble Factor-1 alpha (HIF-1 alpha) selanjutnya meningkatkan ekspresi Vascular Endothelial Growth Factor (VEGH). Hyperbaric Oxygen (HBO) dapat menurunkan ekspresi HIF-1 alpha karena meningkatkan ubiquitinisasi HIF-1 alpha. inilah peluang bagi HBO agar dapat digunakan sebagai salah satu modalitas pendukung pengobatan endometriosis.
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- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
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