A cross sectional study on intestinal and bladder symptoms in gynecologic malignancies.

5115 Background: To find out the prevalence of various intestinal and bladder problems in gynaecologic malignancies as compared with benign conditions. Methods: All participants (case study group n = 200, control group n = 200) were addressed with a questionnaire covering various urinary and bowel symptoms. Between October 2008 and October 2009, 200 patients with history of gynaecologic cancer, treated with surgery, chemotherapy or radiotherapy, attending gynae cancer clinic, IRCH, AIIMS under study group and 200 patients under control group with benign gynaecological conditions were included. Results: The mean age was 50.8 years in study group and 48.8 years in control group with mean parity of 4.1 and 3.8 respectively. Among gynaecological cancers, there were cancer cervix (n = 100), ovarian cancer (n = 50), endometrial cancer (n = 30), vulvo-vaginal cancer (n = 20). Among benign cases, there were chronic cervicitis (n = 55), fibroid uterus (n = 60), pelvic inflammatory diseases (n = 35), endometriosis (n = 25),prolapse uterus (n = 25). We found increased frequency of urine (> 10 per day) (25% vs. 5.4%), nocturia (30% vs. 5.6%), burning micturition (25% vs. 3%), UTI (7.5% vs. 1.6%), urinary hesitancy (2.5% vs. 1.6%), urinary incontinence (36.5% vs. 22.4%), hematuria (15% vs. 1.7%). Among urinary incontinence, urge incontinence was seen in 1% vs. 2.9%,stress incontinence in 27.3% vs. 18%, true incontinence was seen in 7.5% vs. 0.03% and mixed incontinence in 0.7% vs. 1.47%. Among bowel symptoms, there was frequency of stool (35.8% vs. 5.3% ), constipation (30% vs. 7.4% ), gas incontinence (28.9% vs. 5.8%), incontinence of loose stools(44% vs. 2.4%), underwear soil by stool leakage(27% vs. 0.03%), use of any pads (21% vs. 0.03%), feeling of incomplete emptying (37% vs. 4.6%), return to toilet within one hour of defecation (35% vs. 0.02%), inability to defer defecation for > 10 mins (28.9% vs. 4.5%), inability to distinguish between gas and stool (25% vs. 0.03%), associated abdominal pain (30% vs. 6.5%). Conclusions: There is a high prevalence of urinary and bowel problems in gynaecological malignancies. No significant financial relationships to disclose.