Clinical study on ovarian function of patients with adenomyosis after uterine artery embolization

Objective To evaluate the influence on ovarian function of patients with adenomyosis after uterine artery embolization with Pingyangmycin lipiodol emulsion (PLE).Methods Thirty-three patients with adenomyosis undergoing uterine artery embolization(UAE)with PLE whose blood been drawn to measure the level of follicle-stimulating hormone(FSH), luteinizing hormone(LH),estradiol(E2)and prolactin (PRL)before and after UAE of 1,3,6 and 12 months.Simultaneously,these sexual hormones were measured in 45 normal women serving as a normal controlled group.And then the comparison of these serum levels of sexual hormones was also carried out before and after UAE between and within both groups. Results Before this treatment no significant difference was found in the levels of FSH,LH and E2 between the treatment group(33 patients) and the controlled group,but the level of PRL in former was higher than that of the latter.In treatment group there was also no significant difference in the level of FSH,LH and E2 between the pre-UAE and post-UAE, however,the level of PRL was markedly declined at 1,3,6 and 12 months after UAE.Conclusions Transcatheter uterine artery embolization with PLE would not affect ovarian function of patients with adenomyosis,but may be helpful to decrease the level of PRL in these patients.