Genome sequence of the Mediterranean red coral Corallium rubrum

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This paper studied the genome of the Mediterranean red coral Corallium rubrum, an octocoral that builds tiny calcified sclerites and also produces a completely calcified bright red axial skeleton. The authors sequenced and assembled a 655 Mb genome using a MaSuRCA hybrid approach that combined long PacBio reads with short Illumina reads, followed by scaffolding/merging/polishing, resulting in an assembly with 0.95% unknown nucleotides. They note the assembly represents the third published octocoral genome and the first within the order Scleralcyonacea, with the main limitation being that the reported output is a genome assembly description rather than functional validation of red-skeleton biomineralization. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Abstract Objectives: Corallium rubrum , the precious red coral, is an octocoral endemic to the western Mediterranean Sea. Like most octocorals, it produces tiny, calcified structures called sclerites. Uniquely, it also produces a completely calcified axial skeleton that is a bright red color. This combination of color and hardness has made the red coral prized for centuries, leading to extensive fishing and trade for use in jewelry. Understanding how it produces this red skeleton is thus a central question in economics, culture, and biology. To gain insights into this process, we sequenced the C. rubrum genome. Data description: Our C. rubrum genome assembly is 655 megabases (Mb) in size, distributed across 2,910 scaffolds with a very low level of unknown nucleotides (0.95%). We used a pipeline based on the MaSuRCA hybrid assembler, combining long PacBio reads and short Illumina reads, followed by several steps to improve the assembly, including scaffolding, merging, and polishing. This represents the third published genome of an octocoral and the first within the order Scleralcyonacea.
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Genome sequence of the Mediterranean red coral Corallium rubrum | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Genome sequence of the Mediterranean red coral Corallium rubrum Philippe Ganot, Tobias Rausch, Markus Fritz, Didier Zoccola, Xin Wang, and 4 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4582739/v2 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 21 Dec, 2024 Read the published version in BMC Research Notes → Version 2 posted 9 You are reading this latest preprint version Show more versions Abstract Objectives: Corallium rubrum , the precious red coral, is an octocoral endemic to the western Mediterranean Sea. Like most octocorals, it produces tiny, calcified structures called sclerites. Uniquely, it also produces a completely calcified axial skeleton that is a bright red color. This combination of color and hardness has made the red coral prized for centuries, leading to extensive fishing and trade for use in jewelry. Understanding how it produces this red skeleton is thus a central question in economics, culture, and biology. To gain insights into this process, we sequenced the C. rubrum genome. Data description: Our C. rubrum genome assembly is 655 megabases (Mb) in size, distributed across 2,910 scaffolds with a very low level of unknown nucleotides (0.95%). We used a pipeline based on the MaSuRCA hybrid assembler, combining long PacBio reads and short Illumina reads, followed by several steps to improve the assembly, including scaffolding, merging, and polishing. This represents the third published genome of an octocoral and the first within the order Scleralcyonacea. Precious corals Octocoral Scleralcyonacea MaSurCa hybrid Illumina PacBio Biomineralization calcification Full Text Additional Declarations No competing interests reported. Supplementary Files Supplementarymethodsfortheassembly.docx MsGenomeScripts.txt LibrariesandMetrics.xlsx Cite Share Download PDF Status: Published Journal Publication published 21 Dec, 2024 Read the published version in BMC Research Notes → Version 2 posted Editorial decision: Accepted 15 Nov, 2024 Reviews received at journal 13 Nov, 2024 Reviewers agreed at journal 05 Nov, 2024 Reviewers agreed at journal 03 Nov, 2024 Reviewers invited by journal 03 Nov, 2024 Editor assigned by journal 03 Nov, 2024 Editor invited by journal 31 Oct, 2024 Submission checks completed at journal 20 Sep, 2024 First submitted to journal 19 Sep, 2024 You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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