Co-administration of mTor Inhibitors and Carbamazepine May Lead to Ineffectiveness of Therapy: A Case Report of a 24-year-old Man

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Abstract

THE PATIENT A 24-year-old male patient, known to have tuberous sclerosis complex, developed renal epithelioid angiomyolipomas with hepatic metastasis. Everolimus treatment failed, this lead to a switch to temsirolimus treatment without more efficiency that appeared later on was due to drug-drug interaction which was dealt with in an effective manner

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europepmc
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