Selective interaction of some glyconanoparticles with stomach and intestine cancer cells

Abstract Spherical nanoparticles of silver were sensitized by glucose, lactose, dextran, and chitosan. Interactions of these nanoparticles with normal and cancerous tissues of the stomach and the intestine were studied. It was shown that nanoparticles sensitized with lactose interact selectively with cancer cells of the intestine, whereas glucose or dextran-sensitized nanoparticles interact selectively with stomach cancer cells. However, it should be noted that all of these nanoparticles interact to some extent with normal cells, also. Such nanoparticles loaded with anti-cancer drugs may be applied for selective action to these cancer cells