Медичні аспекти у вагітних з істміко-цервікальною недостатністю та безплідністю в анамнезі

The formation of the puberty period is an important background for the female reproductive system in the future and the realization of the childbirth. The objective: to assess medical aspects in women with cervical insufficiency (CI) and infertility associated with anovulation in history. Materials and methods. 60 pregnant women with CI and anovulatory infertility in anamnesis formed the basic group. In these persons the pregnancy occurred after the use of additional reproductive technologies. The control group formed 30 pregnant women without CI and infertility and with physiological pregnancy. Results. In 33.33% individuals in the basic group menarche started in 16 years old and more. While in the control group in all women menarche started in 11–15 years old (χ2=11.00; p<0.001). In the reproductive age all controls (100.00%) had regular menstrual cycle that was in 3.33 times more than the women in the basic group (30.00%; χ2=36.61; p<0.001), 70.00% persons in the basic group had irregular menstruations. The menstruations were always irregular from menarche in 16.64% persons with CI vs none cases among healthy women (χ2=4.06; p=0.04). Endometriosis was diagnosed in 48.33% individuals with CI and infertility, polycystic ovary syndrome – 38.33%, diminished ovarian reserve – 26.67%, hyperandrogenism – 41.67%, ovary cyst – 20.00%. The rate of the infections of the low genital tract before pregnancy was higher in women in the basic group, also 45.00% of these women had gynecological operations (χ2=19.43; p<0.001); thyroid diseases – 25.00% (χ2=5.03; p=0.02), overweight and obesity – 26.67%. Conclusion. Thus, the results of our study indicate that in the persons with cervical infertility and anovulatory infertility in anamnesis disorders in the reproductive system mostly start from the puberty period; the high rate of gynecological diseases, operations on the pelvic organs, pregnancy loss are typical for them.