[Double primary carcinoma of the uterine corpus and ovary]

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A 10-year review of 19 Hong Kong patients with synchronous primary carcinomas of the uterine corpus and ovary found a 78% overall survival rate comparable to stage I ovarian cancer, with tumor grade and positive abdominal washings as significant poor-prognosis indicators.

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Abstract

This article presents 19 patients with double primary carcinoma of the uterine corpus and ovary diagnosed and treated at Queen Mary Hospital, University of Hong Kong in last ten years. 14 patients had typical endometrial adenocarcinoma and endometrioid carcinoma of the ovary (group A), 5 had non-endometrioid carcinoma in the uterine corpus and/or ovary (group B). There is no significant difference in survival rate in group A and B (78.6% and 80%, respectively, mean follow-up 42 months), but the total survival rate in our series is 78%, which is equal to stage I ovarian cancer. The tumor grade and positive abdominal washing were proven to be statistically significant indicators of the poor prognosis (P < 0.05). The result reveals that the prognosis of double primary carcinoma of the uterine corpus and ovary is better and it is necessary to distinguish double primary carcinoma of the uterine corpus and ovary from stage II ovarian cancer and stage III endometrial carcinoma.

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Condition tags

endometriosis

MeSH descriptors

Endometrial Neoplasms Endometriosis Neoplasms, Multiple Primary Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adult Aged Combined Modality Therapy Endometrial Neoplasms Endometrial Neoplasms Endometriosis Endometriosis Female Humans Middle Aged Neoplasms, Multiple Primary Neoplasms, Multiple Primary Neoplasm Staging

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Source provenance

europepmc
last seen: 2026-08-23T09:30:01.253652+00:00
pubmed
last seen: 2026-05-13T22:11:39.448046+00:00
License: public-domain-us · commercial use OK · attribution required
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