Ki-67 Expression is Correlated with Cyst Size and Stage of Endometriosis Ekspresi Ki-67 Berkorelasi dengan Ukuran Kista dan Derajat Endometriosis
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Ki-67 expression showed a significant and strong positive correlation with both the size of endometriotic cysts and the stage of endometriosis.
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Abstract
Abstract
Objectives: To analyze the association between Ki-67 expression with the cyst size and stage of endometriosis, and the correlation strength between them.
Methods: A cross-sectional analytic observational study involving 56 paraffin blocks from subjects diagnosed with endometriosis, who had undergone laparotomy or laparoscopic surgery. The study is conducted in Dr. Hasan Sadikin Hospital in September-November 2012.
Results: Shows a significant association between Ki-67 expression and the size of endometriotic cyst (p < 0.0001), also with a strong correlation (r = 0.55) according to Guilford criteria. There is also a significant association between Ki-67 expression and the endome¬triosis stage (p < 0.0001), with a strong correlation (r = 0.564) ac¬cording to Guilford criteria.
Conclusion: Ki-67 expression is correlated with the cyst size and stage of endometriosis.
[Indones J Obstet Gynecol 2013; 1-3: 124-8]
Keywords: endometriosis stage, endometriotic cyst size, Ki-67
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Cites (4)
- Endometriosis 2010
- Immunohistochemical analysis of proliferative activity and steroid receptor expression in peritoneal and ovarian endometriosis 1997
- Endometrium from women with endometriosis shows increased proliferation activity 2009
- Ki-67, oestrogen receptor, and progesterone receptor proteins in the human rete ovarii and in endometriosis. 1999
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