Endometriose als Einflussfaktor bei Transfer kryokonservierter Embryonen

The paper studies how endometriosis affects outcomes of assisted reproduction cycles using cryopreserved embryo thaw transfers, building on prior findings that overall outcomes can be similar for fresh versus frozen embryos when embryo quality is comparable. In a retrospective analysis of 510 thaw cycles, 90 cycles involved patients diagnosed with endometriosis and 420 served as controls, and the authors compared pregnancy rates, thaw rates, abortion rates, live birth rates, and characteristics/quality of transferred embryos. With similar baseline factors in both groups, pregnancy rate differed (25.0% in the endometriosis group vs 35% in controls), while other outcome measures and embryo quality were also evaluated. The paper concludes that endometriosis may influence success in cryopreserved embryo cycles, but it does not determine whether the cause lies in the endometrium or in embryo quality, noting prior group data indicating differences in oocyte quality with endometriosis. This paper is centrally about endometriosis — it investigates how endometriosis impacts pregnancy outcomes in cycles with cryopreserved embryo transfers.

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