Accuracy of magnetic resonance in deeply infiltrating endometriosis: a systematic review and meta-analysis

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Abstract

OBJECTIVE: To estimate the accuracy of pelvic magnetic resonance imaging (MRI) in the diagnosis of deeply infiltrating endometriosis (DIE). METHODS: A comprehensive search of the Medline, Pubmed, Lilacs, Scopus, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Biomed Central, and ISI Web of Science databases was conducted from January 1990 to December 2013. The medical subject headings (MeSHs) and text words "deep endometriosis", "deeply infiltrating endometriosis", "DIE", "magnetic resonance", and "MRI" were searched. Studies that compared the parameters of pelvic MRIs with those of paraffin-embedded sections for the diagnosis of DIE were included. RESULTS: Twenty studies were analyzed, which included 1,819 women. Pooled sensitivity and specificity were calculated across eight subgroups: for all sites, these were 0.83 and 0.90, respectively; for the bladder, 0.64 and 0.98, respectively; for the intestine, 0.84 and 0.97, respectively; for the pouch of Douglas, 0.89 and 0.94, respectively; for the rectosigmoid, 0.83 and 0.88, respectively; for the rectovaginal, 0.77 and 0.95, respectively; for the uterosacral ligaments, 0.85 and 0.80, respectively; and for the vagina and the posterior vaginal fornix, 0.82 and 0.82, respectively. CONCLUSION: In summary, pelvic MRI is a useful preoperative test for predicting the diagnosis of multiple sites of deep infiltrating endometriosis.
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Abstract

Objective To estimate the accuracy of pelvic magnetic resonance imaging (MRI) in the diagnosis of deeply infiltrating endometriosis (DIE).

Methods

A comprehensive search of the Medline, Pubmed, Lilacs, Scopus, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Biomed Central, and ISI Web of Science databases was conducted from January 1990 to December 2013. The medical subject headings (MeSHs) and text words “deep endometriosis”, “deeply infiltrating endometriosis”, “DIE”, “magnetic resonance”, and “MRI” were searched. Studies that compared the parameters of pelvic MRIs with those of paraffin-embedded sections for the diagnosis of DIE were included.

Results

Twenty studies were analyzed, which included 1,819 women. Pooled sensitivity and specificity were calculated across eight subgroups: for all sites, these were 0.83 and 0.90, respectively; for the bladder, 0.64 and 0.98, respectively; for the intestine, 0.84 and 0.97, respectively; for the pouch of Douglas, 0.89 and 0.94, respectively; for the rectosigmoid, 0.83 and 0.88, respectively; for the rectovaginal, 0.77 and 0.95, respectively; for the uterosacral ligaments, 0.85 and 0.80, respectively; and for the vagina and the posterior vaginal fornix, 0.82 and 0.82, respectively.

Conclusion

In summary, pelvic MRI is a useful preoperative test for predicting the diagnosis of multiple sites of deep infiltrating endometriosis. Similar content being viewed by others

References

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Accessed 24 April 2014 Acknowledgment This review was funded by the Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. The sponsor of this study had no role in the study’s design, data collection, data analysis, data interpretation or writing of the report or in the decision to submit the paper for publication. Conflict of interest The authors report no conflict of interest. Author information Authors and Affiliations Corresponding author Rights and permissions About this article Cite this article Medeiros, L.R., Rosa, M.I., Silva, B.R. et al. Accuracy of magnetic resonance in deeply infiltrating endometriosis: a systematic review and meta-analysis. Arch Gynecol Obstet 291, 611–621 (2015). https://doi.org/10.1007/s00404-014-3470-7 Received: Accepted: Published: Issue date: DOI: https://doi.org/10.1007/s00404-014-3470-7

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Abdominal Cavity Adnexa Uteri Endometriosis Magnetic Resonance Imaging Pelvis Abdominal Cavity Adnexa Uteri Endometriosis Female Humans Magnetic Resonance Imaging Pelvis Predictive Value of Tests Preoperative Care Preoperative Care Sensitivity and Specificity Vagina Vagina

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