Valentino’s syndrome in acute pancreatitis female patient: A case report with literature review

Abstract INTRODUCTION: Valentino’s syndrome is an unusual right iliac fossa pain due to perforation of a duodenal peptic ulcer through the paracolic sulcus leading to local irritation. The aim of this study is to report a case of Valentino’s syndrome from acute pancreatitis with a brief literature report. CASE PRESENTATION: A 50-year-old lady presented with diffuse irradiated abdominal pain and swelling of about 6 h duration, associated with nausea, vomiting, and inability to flatus. There was positive upper abdominal and right iliac fossa tenderness. The abdominal computed tomography (CT) scan showed acute pancreatitis appearance with fat stranding and fluid collection from the peripancreatic to the right lower quadrant. Serum amylase and lipase were elevated. Therefore, the initial diagnoses were acute pancreatitis and appendicitis. Conservative management was done because of poor hemodynamics, laboratory work-up, and the lack of medical speciality to perform surgery. The patient was then transferred to another hospital with adequate facilities. CONCLUSION Valentino’s syndrome from acute pancreatitis is an extremely rare case, presented with vague symptoms, diagnosed by abdominal CT scan. Clinical diagnosis could be challenging for clinicians.