Tumor‐like cystic endosalpingiosis of the uterus with florid epithelial proliferation

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AI-generated summary by claude@2026-06, 2026-06-07

This case describes a large, non-neoplastic cystic endosalpingiosis of the uterus presenting as a uterine mass with florid epithelial proliferation, mimicking ovarian cancer.

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Abstract

Mass-like cystic endosalpingiosis is very rare. The author reports such a lesion with histologic features of endosalpingiosis of the uterus with florid epithelial proliferation in a 51-year-old female who complained of lower abdominal pain. Preoperatively, it was considered to be left-sided ovarian cancer. Intraoperatively, a subserosal, sessile polypoid mass with multiple cysts in the uterine fundus measuring 12 x 6.5 x 5.5 cm was found. Histologically, it was composed of multiple cysts lined by benign-appearing tubal epithelium and bland smooth muscular and myofibromatous stroma. Part of the epithelium exhibited marked papillarity and tufting. Features of conventional endometriosis were present focally. Pathologists and clinicians should be aware of the existence of this type of non-neoplastic lesion, mass-like cystic endosalpingiosis, and should avoid overdiagnosis and overtreatment.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Fallopian Tube Diseases Uterine Diseases Cysts Cysts Cysts Diagnosis, Differential Endometriosis Endometriosis Endometriosis Fallopian Tube Diseases Fallopian Tube Diseases Fallopian Tube Diseases Female Histocytochemistry Humans Middle Aged Uterine Diseases Uterine Diseases Uterine Diseases

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europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
last seen: 2026-05-13T22:12:38.158000+00:00
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