Analysis of Clinical Characteristics of 145 MGTB patients in three provincial teaching hospitals in Gansu province

Abstract Objective To explore the strengths and weaknesses of current diagnostic and therapeutic approaches for MGTB. Methods The clinical data of 145 patients diagnosed with MGTB from January 2013 to September 2023 were retrospectively analyzed to determine better diagnosis and treatment methods to guide clinical practice. Results Among 145 male patients with MGTB, 29 (20%) were accompanied by urinary TB, and 116 (80%) were only associated with MGTB. TSPOT and ultrasound are the most valuable laboratory and imaging methods. Surgical resection was still the first choice for the cure of germline tuberculosis, 113 patients chose surgical resection, the resection rate was 77.93%, the cure rate was 75%, and the recurrence and progression rate were 5.36%. The symptoms of MGTB are insidious, and the accurate diagnosis requires a combination of laboratory tests and imaging examinations. TSPOT and ultrasound are the most valuable diagnostic methods and are recommended as the first choice. Conclusion Preoperative and postoperative anti-tuberculosis drug therapy is necessary to reduce the incidence of complications and the risk of recurrence. When treating germline tuberculosis, we should pay attention to the patient's sexual function and fertility.