Evaluation of Blood Glucose As A Biomarker For On Spot Detection of Bovine Trypanosomosis In Emergent Nations

Abstract Trypanosomosis or surra has been declared notifiable multispecies animal disease by World Organization for Animal Health. Diagnosis of trypanosomosis is a challenging task in field condition because none of reported signs is pathognomonic resulting in failure of treatment either inappropriate or delay in treatment. In spite of this, low hemoglobin level and hypoglycaemia are consistent hemato-biochemical changes in trypanosomosis. Therefore taking into consideration of both these two changes, tentative diagnosis of trypanosomosis could be done in low resource laboratory situated in rural area. With the development of eco and user friendly pen-side diagnostic, effective management of animal trypanosomosis could only be possible. Out of 123 buffaloes, 21 buffaloes found positive by PCR were showing average temperature 105.130F±0.983, blood glucose 32.319±9.760 and haemoglobin 8.60±1.485. Likewise Value of blood glucose (glucometer- 95% CI 68.488 to 77.141 and semiautomatic blood analyzer- CI 64.637 to 74.087) and haemoglobin (95% CI 95.743 to 97.314) were found statistically highly significant (P<0.001) with body temperature. Lower the blood glucose level in fevered animals may suspect the trypanosomosis. In these cases portable blood glucose meter may help the field veterinarian for on spot estimation of blood glucose level of fevered animals. An on spot estimation of lowered glucose level, anaemia and high temperature increases the probability of trypanosomosis. So that timely treatment of infected animal could be possible in rural area without wasting of time to get the report from full equipped laboratory. This might be the first time reported method for early diagnosis of trypanosomosis.