Rapid and Efficient Route for Chitosan Blends with Fish Collagen and Aloe Vera Exudate

Rapid and Efficient Route for Chitosan Blends with Fish Collagen and Aloe Vera Exudate | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Rapid and Efficient Route for Chitosan Blends with Fish Collagen and Aloe Vera Exudate Pâmella Rayo de Luar Campos Gonçalves, Roseane Silva Penha, Jaciene Jesus Cardoso Rocha, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3883224/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Biomaterials based on chitosan (CS), in combination with other biopolymers such as collagen (CL) and aloe vera (AV), are of interest to medicine as well as the pharmaceutical and cosmetic industries, with a wide range of applications in those fields due to their characteristics of non-toxicity, biocompatibility, low cost and biodegradability. The combination of chitosan and those biopolymers has been frequently used as ointments for burns and other skin injuries. In this work, the selective precipitation and co-precipitation techniques were used to prepare and characterize chitosan blends combined with different portions of fish collagen and aloe vera biopolymers. The employed methods are simple, fast and safe, and require minimal infrastructure and prioritize the interaction between the biopolymers or their miscibility, with no segregated phases observed in the obtained blends. The syntheses were analyzed according to their yields, 4-hydroxyproline content (in CS/CL blends), and the materials were characterized by bromatological analyses (CS, CL, and AV), viscosity, Fourier-transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy. The experimental results have confirmed the occurrence of spontaneous interactions between the biopolymers through the formation of blends, which exhibited individual characteristics proportional to the variation of biopolymers in chitosan, thus indicating the efficiency of the syntheses routes. biomaterials green syntheses sustainable materials natural polymers. Full Text Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3883224","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":272791322,"identity":"530b17ec-b9e5-49b7-a051-755d06552136","order_by":0,"name":"Pâmella Rayo de Luar Campos Gonçalves","email":"","orcid":"","institution":"Universidade Federal do Maranhao","correspondingAuthor":false,"prefix":"","firstName":"Pâmella","middleName":"Rayo de Luar Campos","lastName":"Gonçalves","suffix":""},{"id":272791323,"identity":"536aef6e-b122-42ed-a12d-2920df513893","order_by":1,"name":"Roseane Silva Penha","email":"","orcid":"","institution":"Universidade Federal do Maranhao","correspondingAuthor":false,"prefix":"","firstName":"Roseane","middleName":"Silva","lastName":"Penha","suffix":""},{"id":272791324,"identity":"0d90924a-55a1-4d29-b68a-33f42e0477e6","order_by":2,"name":"Jaciene Jesus Cardoso Rocha","email":"","orcid":"","institution":"Universidade Federal do Maranhao","correspondingAuthor":false,"prefix":"","firstName":"Jaciene","middleName":"Jesus Cardoso","lastName":"Rocha","suffix":""},{"id":272791325,"identity":"bef20fb0-8a12-48da-9e64-04cc25e70944","order_by":3,"name":"Amanda Ribeiro Guimarães","email":"","orcid":"","institution":"Euskal Herriko Unibertsitatea: Universidad del Pais Vasco","correspondingAuthor":false,"prefix":"","firstName":"Amanda","middleName":"Ribeiro","lastName":"Guimarães","suffix":""},{"id":272791326,"identity":"c9d7c501-71cd-4962-9771-11b361fcb573","order_by":4,"name":"Cicero Weelington Brito Bezerra","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA0UlEQVRIiWNgGAWjYFACHgZmKIvxAYMNkJIgQQuzAUMaiVrYJIjSwj8j9wBzQUWdnPnsw8+qeRK2yTNI9z7Aq0XiRl4C84wzbMYy59LMbvMk3DZskDlugFeLgXSOATNvG0/iDB4Gs9u8P24zNkik4XcYRMs/ifoZPOzfioG22BOppcEgQYKHx4wZqCWRoBaJ++8SDs84lmA4g4enWHJOwu3kNplj+LXw95w9+Ligpk5egod944c3Cbdt+6Xb8GsBgQMoPDbCGkbBKBgFo2AUEAIAW0E73KyF0kUAAAAASUVORK5CYII=","orcid":"https://orcid.org/0000-0001-9058-9469","institution":"Universidade Federal do Maranhao","correspondingAuthor":true,"prefix":"","firstName":"Cicero","middleName":"Weelington Brito","lastName":"Bezerra","suffix":""}],"badges":[],"createdAt":"2024-01-21 02:38:01","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-3883224/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-3883224/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":63403055,"identity":"90a64a0e-63cc-4c6b-8404-1a17e2b68a51","added_by":"auto","created_at":"2024-08-27 19:30:29","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":979585,"visible":true,"origin":"","legend":"","description":"","filename":"RapidandEfficientRouteforChitosanBlends.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3883224/v1_covered_a4f6e1b1-151b-434b-bed2-c6b319d9137f.pdf"}],"financialInterests":"","formattedTitle":"Rapid and Efficient Route for Chitosan Blends with Fish Collagen and Aloe Vera Exudate","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"biomaterials, green syntheses, sustainable materials, natural polymers.","lastPublishedDoi":"10.21203/rs.3.rs-3883224/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3883224/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"Biomaterials based on chitosan (CS), in combination with other biopolymers such as collagen (CL) and aloe vera (AV), are of interest to medicine as well as the pharmaceutical and cosmetic industries, with a wide range of applications in those fields due to their characteristics of non-toxicity, biocompatibility, low cost and biodegradability. 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