Effects of PKF 115–584 on total and active forms of MMP-2 and MMP-9.

A, B: Total and active forms of MMP-2 in non-treated and PKF 115–584–treated endometrial epithelial (A) and stromal (B) cells of patients with and without endometriosis. C, D: Total and active forms of MMP-9 in non-treated and PKF 115–584–treated endometrial epithelial (C) and stromal (D) cells of patients with and without endometriosis. Endo (+): Endometrium of patients with endometriosis (epithelial cells: n = 4, stromal cells: n = 4). Endo (–): endometrium of patients without endometriosis (epithelial cells: n = 3, stromal cells: n = 3). Values are normalized to the total protein content of the culture supernatants. Results are presented as the mean+SEM. a: p<.05 versus non-treated endometrial epithelial or stromal cells of patients without endometriosis. b: p<.05 versus PKF 115–584–treated endometrial epithelial or stromal cells of patients without endometriosis.MMP-9