[The competitive relations of tamoxifen and estradiol at the level of the plasma membranes of the target cells]

E N Mineeva, Mineeva EN
Farmakologiia i toksikologiia · 1990 · PMID:2081562
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Abstract

The specific binding of an antiestrogen tamoxifen to receptors of estradiol of target cells plasmic membranes of the human endometrium was studied in some hyperplastic processes. The relative binding activity of tamoxifen was determined. Tamoxifen was found to compete with estradiol for binding to plasmic membranes of the endometrial cells.

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Condition tags

endometriosis

MeSH descriptors

Estradiol Receptors, Estradiol Tamoxifen Adenocarcinoma Adenocarcinoma Binding, Competitive Binding, Competitive Cell Membrane Cell Membrane Endometriosis Endometriosis Endometrium Endometrium Estradiol Female Humans In Vitro Techniques Polyps Polyps Receptors, Estradiol

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europepmc
last seen: 2026-08-09T06:10:49.860119+00:00
pubmed
last seen: 2026-05-13T22:12:05.481982+00:00
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Courtesy of the U.S. National Library of Medicine