Desquamative interstitial pneumonia and scar cancer of the lung complicating generalised neurofibromatosis

De Scheerder I, I De Scheerder, W Elinck, Elinck W, Van Renterghem D, D Van Renterghem, C Cuvelier, Cuvelier C, Tasson J, J Tasson, Van der Straeten M, M Van der Straeten
European journal of respiratory diseases · 1984 · vol. 65(8) , pp. 623–6 · PMID:6440805
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This case report describes a 40-year-old male with generalized neurofibromatosis who developed desquamative interstitial pneumonia and an adenosquamous carcinoma in the lung, discussing the pathogenesis of scar cancer in this condition.

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Abstract

A 40-year-old male patient with known generalised neurofibromatosis presented with a radiological pattern of interstitial fibrosis and a coin lesion in the left lung. Closed lung biopsy revealed an adenosquamous carcinoma. The pulmonary complications of generalised neurofibromatosis and the possible pathogenesis of scar cancer in this condition are discussed.

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MeSH descriptors

Adenocarcinoma Carcinoma, Squamous Cell Neurofibromatosis 1 Pulmonary Fibrosis Solitary Pulmonary Nodule Adenocarcinoma Adenocarcinoma Adult Carcinoma, Squamous Cell Carcinoma, Squamous Cell Cicatrix Cicatrix Humans Lung Lung Lung Neoplasms Lung Neoplasms Lung Neoplasms Male Neurofibromatosis 1

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europepmc
last seen: 2026-10-18T09:30:06.152893+00:00
pubmed
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