Which kind of classification is more suitable for Herlyn–Werner–Wunderlich syndrome

Abstract Background: To analyze the clinical characteristics of patients with Herlyn–Werner–Wunderlich syndrome (HWWs) in two classification methods. Methods: 87 HWWs patients syndrome admitted to the Shengjing hospital of China Medical University between April 2003 to June 2020 were retrospectively reviewed. Results: Type II of average age at time of diagnosis (25.11±8.96) was significantly longer than the other two types(13.06±2.55; 13.06±2.55). The menarche and the interval between menarche and time of diagnosis was significant difference between types I and II. The average age at time of diagnosis, the menarche and the interval between menarche and time of diagnosis was significant difference between classification I and II. Cystic mass in vaginal wall was a significant difference between type I and II. Endometriosis of type I and II was a more common than type III. Sex life was a significant difference between type I and II. Mediastinum of uterus of type II was a more common than type I and III. The time of diagnosis, menarche, interval between menarche and time of diagnosis, cystic mass in vaginal wall, abnormal vaginal discharge, sex life, changes of urination and defecation and mediastinum of uterus were significant difference between classification 1 and classification 2. The site of olique septum vaginalis was significant difference in two classification methods. The absence of kidney in HWWs type was significant difference in two classification methods. Conclusion: Type I HWWs should be suspected in cases involving adolescent girls presenting with cyclical pelvic pain, change of urination and defecation. Two classification can be easy to treat in clinical work.