COVID 19 infection as a cause of COPD exacerbation in a vaccinated patient

According to a largest systematic review, COPD is a significant risk factor for hospitalization, ICU admission and mortality in patients with COVID-19. According to British Thoracic Society patients with severe COPD are considered Clinically Extremely Vulnerable and should receive COVID-19 vaccine. Pfizer's vaccine showed significant effectiveness against COVID-19. In our case patient had severe form of COPD exacerbation after vaccination, which required hospitalization and the non-invasive ventilation but without intubation and radiology verified pneumonia.