Anxiety and depression in women with asthma prior to fertility treatment

Emilia Yifei Huang; Anne Vejen Hansen; Casper Tidemandsen; Nina la Cour Freiesleben; Henriette Svarre Nielsen; Vibeke Backer; Charlotte Suppli Ulrik

doi:10.1080/20018525.2023.2221376

Anxiety and depression in women with asthma prior to fertility treatment

Emilia Yifei Huang, Anne Vejen Hansen, Casper Tidemandsen, Nina la Cour Freiesleben, Henriette Svarre Nielsen, Vibeke Backer, Charlotte Suppli Ulrik

In: European Clinical Respiratory Journal · 2023 · vol. 10(1) , pp. 2221376 · doi:10.1080/20018525.2023.2221376 · PMID:37313367 · PMC10259298 · W4380149149

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Abstract

Objective: We investigate symptoms of anxiety and depression among women with asthma prior to fertility treatment. Methods: This is a cross-sectional study of women screened for eligibility to the PRO-ART study (RCT of omalizumab versus placebo in asthmatic women undergoing fertility treatment (NCT03727971)). All participants were scheduled for in vitro fertilization (IVF) treatment at four public fertility clinics in Denmark. Data on demographics and asthma control (ACQ-5) were obtained. Symptoms of anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS-A and D, respectively) and defined as being present on both subscales if a score >7 was obtained. Spirometry, diagnostic asthma test, and measurement of fractional exhaled nitric oxide (FeNO) were conducted. Results: = 0.03). Conclusions: More than 25% of women with asthma prior to fertility treatment had self-reported symptoms of anxiety, and just below 5% had self-reported depressive symptoms, possibly related to uncontrolled asthma.

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Asthma affects time to pregnancy and fertility: a register-based twin study 2013

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[1] Asthma affects time to pregnancy and fertility: a register-based twin study 2013