The significance of serum IL-8 level in diagnosis of endometriosis

This study aimed to evaluate the value of serum interleukin(IL)-8 levels in diagnosis of endometriosis.Total of 80 patients with endometriosis and 60 healthy controls were recruited in this study.Preoperative blood samples were collected from 80 patients.Then IL-8 and CA-125 levels in the serum was measured by ELISA and microparticle enzyme immunoassay,respectively.We found that the serum concentration of IL-8 in patients with endometriosis was significantly higher than that in healthy controls.The serum IL-8 threshold(26 pg/ml) had a higher sensitivity(71.3%) for diagnosing endometriosis as compared with serum CA-125.Thus,we concluded that measuring of serum IL-8 concentration may be a valuable tool in diagnosing endometriosis.