Research progress on the relationship between adipose tissue and adipokines and endometriosis

Adipose tissue not only has the function of energy storage and heat preservation, as the largest endocrine organ in human body, can also be involved in the human body immunity, inflammation, lipid metabolism, angiogenesis and so on, through the secretion of leptin, adiponectin and other adipokines, adhesion molecule such as intercellular cell adhesion molecule-1 (ICAM-1), and angiogenic factors such as vascular endothelial growth factor (VEGF). Body mass index (BMI), serum or intraperitoneal leptin, resistin, adiponectin concentrations, such as adhesion molecules and angiogenesis factors between endometriosis (EMS) patients and women without EMS were significant differences. It may be that adipose tissue and adipose factors promote adhesion, invasion and angiogenesis of ectopic endometrium by promoting inflammation, promoting angiogenesis, and producing insulin resistance. The role of adipose tissue and its secreted adipokines, adhesion molecules and angiogenesis factors in the development of EMS are reviewed. Key words: Endometriosis (EMS); Adipose tissue; Adipokines